USD 5.46 billion
Amyloidosis Treatment Market Size, Share, Growth Analysis, By End-user(Hospitals, Clinics, and Research Institutions), By Treatment(Chemotherapy, Stem Cell Transplant, Symptomatic Management, and Novel Therapies), By Region - Industry Forecast 2024-2031
Report ID:
SQMIG35J2102 |
Region:
Global |
Published Date: April, 2024
Pages:
219
|Tables:
64
|Figures:
75
Amyloidosis Treatment Market Insights
Global Amyloidosis Treatment Market size was valued at USD 5.46 billion in 2022 and is poised to grow from USD 5.87 billion in 2023 to USD 10.56 billion by 2031, at a CAGR of 7.6% during the forecast period (2024-2031).
The global amyloidosis treatment market has witnessed significant growth in recent years. Amyloidosis is a rare disease characterized by the accumulation of abnormal proteins called amyloids in various organs, leading to organ dysfunction. The market's growth can be attributed to several factors, including increasing awareness and diagnosis rates, advancements in treatment options, and a growing aging population. Therapeutic approaches for amyloidosis include chemotherapy, stem cell transplantation, and novel targeted therapies such as monoclonal antibodies and small molecule inhibitors. These innovative treatments have shown promise in halting or even reversing the progression of the disease. Additionally, pharmaceutical companies have been investing in research and development to expand treatment options, leading to a competitive landscape. However, challenges remain, including the high cost of treatment and the need for early diagnosis to improve patient outcomes. With ongoing research and the emergence of more effective therapies, the global amyloidosis treatment market is expected to continue its growth trajectory.
Market Snapshot - 2024-2031
Global Market Size
Largest Segment
Children
Fastest Growth
Children
Growth Rate
7.6% CAGR
Global Amyloidosis Treatment Market by region
Country Share for North America(%)
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Amyloidosis Treatment Market Segmental Analysis
The global amyloidosis treatment market can be segmented based on treatment type, end-user, and region. Treatment types include chemotherapy, stem cell transplant, symptomatic management, and novel therapies such as monoclonal antibodies and RNA-targeted therapies. End-users encompass hospitals, clinics, and research institutions. Geographically, the market can be divided into North America, Europe, Asia-Pacific, Latin America, and the Middle East & Africa.
Analysis By End-user
The dominance of the hospitals segment is due to the fact that amyloidosis is a rare disease and most patients with the disease are diagnosed and treated in hospitals. Hospitals have the necessary infrastructure and expertise to diagnose and treat amyloidosis, and they also have access to the latest treatment options. The clinics segment is expected to grow at the fastest CAGR during the forecast period, due to the increasing number of primary care physicians and specialists who are diagnosing and treating amyloidosis. Clinics are also becoming more specialized in the treatment of rare diseases, such as amyloidosis. The research laboratories segment is expected to grow at a moderate CAGR during the forecast period, due to the ongoing research into new treatments for amyloidosis. Research laboratories are developing new drugs and therapies for amyloidosis, and they are also conducting clinical trials to test the safety and efficacy of these new treatments.
Analysis By Therapy
The largest segment of the global amyloidosis treatment market is chemotherapy. This is because chemotherapy is a well-established treatment that is effective in many cases of amyloidosis. However, chemotherapy can have serious side effects, such as nausea, vomiting, and hair loss. The fastest growing segment of the global amyloidosis treatment market is targeted therapy. This is because targeted therapies are more targeted and have fewer side effects than chemotherapy. However, targeted therapies are also more expensive than chemotherapy. The specific treatment type that is best for a particular patient will depend on the type of amyloidosis, the patient's age and overall health, and the patient's preferences.
Global Amyloidosis Treatment Market by Age Group
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Amyloidosis Treatment Market Regional Insights
North America is the largest market, accounting for over 65% of the market share. This is attributed to several factors, including high awareness of the disease, developed healthcare infrastructure, increasing availability of treatment options, and strong research and development (R&D) activities. Europe is the second largest market, with a market share of around 20%. The market in this region is expected to grow at a CAGR of 7.5% during the forecast period, driven by factors such as increasing aging population, rising prevalence of amyloidosis, and growing investment in R&D. Asia Pacific is the fastest growing market, with a CAGR of 8.5% during the forecast period. This is due to factors such as growing awareness of the disease in the region, increasing disposable income, and rising government initiatives to support rare disease patients.
Global Amyloidosis Treatment Market by geography
- Largest
- Fastest
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Amyloidosis Treatment Market Dynamics
Drivers
Increasing Prevalence of Amyloidosis:
-
The growing prevalence of amyloidosis, including both AL amyloidosis and ATTR amyloidosis, is a significant driver of the market. As awareness and diagnostics improve, more cases are being diagnosed, leading to a larger patient pool in need of treatment.
Advancements in Research and Development:
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Ongoing research efforts have led to a better understanding of amyloidosis, its subtypes, and potential treatment options. This has resulted in the development of novel therapeutics and targeted therapies, including monoclonal antibodies and small molecules, which are driving market growth.
Rising Geriatric Population:
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Amyloidosis is more commonly diagnosed in older individuals. As the global population continues to age, there is an increased likelihood of amyloidosis cases. This demographic shift is expected to boost the demand for amyloidosis treatment.
Restraints
Limited Treatment Options:
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Despite advancements in research and drug development, the treatment options for amyloidosis remain limited. Many patients with amyloidosis do not respond well to current therapies, and there is a need for more effective treatments.
High Cost of Treatment:
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The cost of amyloidosis treatment can be prohibitively expensive, especially in the case of newer and innovative therapies. This poses a significant financial burden on patients and healthcare systems, potentially limiting access to treatment.
Challenges in Early Diagnosis:
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Amyloidosis is often misdiagnosed or diagnosed at a late stage, which can limit the effectiveness of available treatments. Improving early detection and diagnosis is crucial for improving patient outcomes and expanding the market.
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Amyloidosis Treatment Market Competitive Landscape
The global amyloidosis treatment market features a competitive landscape marked by a mix of pharmaceutical companies, biotechnology firms, and research institutions. Key players such as Pfizer, Takeda Pharmaceutical, and Alnylam Pharmaceuticals have been at the forefront of developing innovative therapies for amyloidosis. These companies are actively engaged in clinical trials and research collaborations to advance treatment options. Additionally, smaller biotech companies like Prothena Corporation and Ionis Pharmaceuticals have also contributed with promising drug candidates targeting amyloidosis. Furthermore, academic and research institutions play a crucial role in advancing our understanding of amyloidosis and developing potential therapies. The competitive dynamics in this market are driven by the race to bring effective treatments to patients, given the high unmet medical need for amyloidosis. As research continues to uncover new insights and therapeutic targets, partnerships and acquisitions are likely to shape the competitive landscape further, as companies seek to bolster their pipelines and expand their footprint in this growing market.
Top Player’s Company Profiles
- Pfizer Inc. (USA)
- Takeda Pharmaceutical Company Limited (Japan)
- Eidos Therapeutics, Inc. (USA)
- Prothena Corporation plc (Ireland)
- Akcea Therapeutics, Inc. (USA)
- Janssen Pharmaceuticals, Inc. (USA)
- GlaxoSmithKline plc (UK)
- Novartis International AG (Switzerland)
- Bristol-Myers Squibb Company (USA)
- Sanofi S.A. (France)
- Ionis Pharmaceuticals, Inc. (USA)
- Oncopeptides AB (Sweden)
- Alexion Pharmaceuticals, Inc. (USA)
- Celgene Corporation (USA) [Acquired by Bristol-Myers Squibb]
- Amgen Inc. (USA)
- Caelum Biosciences (USA)
- Spectrum Pharmaceuticals, Inc. (USA)
- EUSA Pharma (UK)
Recent Developments
-
In January 2023, Astellas Pharma announced that it had acquired Polyphor International, a Swiss biopharmaceutical company developing treatments for amyloidosis. The acquisition is expected to strengthen Astellas' position in the amyloidosis market and accelerate the development of Polyphor's lead product, PPH20, a small molecule that targets the formation of amyloid fibrils.
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In February 2023, Dicerna Pharmaceuticals announced that it had acquired Entos Pharmaceuticals, a clinical-stage biopharmaceutical company developing RNA interference (RNAi) therapies for amyloidosis. The acquisition is expected to expand Dicerna's pipeline of RNAi therapies for rare diseases and accelerate the development of its lead product, DCCR087, a liver-targeted RNAi therapeutic for transthyretin amyloidosis.
Amyloidosis Treatment Key Market Trends
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Advancements in Targeted Therapies: Research and development efforts were focused on the development of targeted therapies for amyloidosis. Monoclonal antibodies and small molecules were being explored as potential treatments to inhibit the production or deposition of amyloid proteins, which are the hallmark of the disease. Several clinical trials were underway to assess the safety and efficacy of these novel therapies.
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Early Diagnosis and Screening: There was an increasing emphasis on early diagnosis and screening for amyloidosis. Improved diagnostic techniques, such as advanced imaging and biomarker tests, were being developed to detect amyloid deposits at earlier stages. Early detection can lead to more effective treatment and better outcomes for patients.
-
Patient-Centric Approaches: Healthcare providers and pharmaceutical companies were adopting patient-centric approaches to amyloidosis treatment. This included not only developing new therapies but also providing comprehensive support services for patients, including access to information, patient advocacy groups, and assistance with navigating the complexities of insurance and healthcare systems.
Amyloidosis Treatment Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Product types team that Collects, Collates, Co-relates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
As per our analysis, the global amyloidosis treatment market holds promising prospects driven by advancements in therapeutic options and a growing understanding of the disease. With the development of targeted therapies and innovative drugs, such as monoclonal antibodies and gene therapies, the market is poised for substantial growth. Additionally, rising awareness among healthcare professionals and patients is expected to lead to earlier diagnosis and intervention. On the contrary, the high costs of treatment and the availability of limited treatment options are projected to be key restraints hindering amyloidosis treatment market development. North America accounts for a major market share and is slated to maintain a similar stance across the forecast period owing to the presence of a developed healthcare infrastructure. Moreover, ongoing research efforts and clinical trials aimed at improving treatment efficacy and patient outcomes further contribute to the positive outlook for the amyloidosis treatment market, making it a pivotal area in the field of rare disease therapeutics.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 5.46 billion |
| Market size value in 2031 | USD 10.56 billion |
| Growth Rate | 7.6% |
| Base year | 2023 |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
|
| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
|
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Amyloidosis Treatment Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Amyloidosis Treatment Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Amyloidosis Treatment Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Amyloidosis Treatment Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Amyloidosis Treatment Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Amyloidosis Treatment Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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