Aptamers Market Size, Share, Growth Analysis, By Type(DNA Aptamers), By Technology(SELEX, Other Technologies, Research & Development, Others), By Application(Therapeutics Development, Research & Development, Diagnostics, Other Applications), By End User(Pharmaceutical & Biotechnology Companies, Academic & Government Research Institutes, Contract Research Organizations, Other End Users), By Region - Industry Forecast 2024-2031


Report ID: SQMIG35E2038 | Region: Global | Published Date: September, 2024
Pages: 219 |Tables: 62 |Figures: 77

Aptamers Market Insights

Global Aptamers Market size was valued at USD 155 million in 2022 and is poised to grow from USD 182.59 million in 2023 to USD 677.08 million by 2031, growing at a CAGR of 17.80% during the forecast period (2024-2031).

Rapidly increasing prevalence of chronic diseases around the world and growing use of targeted therapeutics for the treatment of the same are projected to drive up the demand for aptamers over the coming years. Surging demand for early diagnostics and rising investments in the development of novel diagnostic technologies are also expected to benefit aptamers market growth over the coming years. Advancements in SELEX technology are also anticipated to play a crucial role in expanding the business scope of aptamers market players going forward. High investments in medical R&D around the world, rising use of genetic therapies and technologies, and rising awareness regarding the benefits of aptamers are also expected to bolster aptamers market development in the future. On the contrary, short half-life, availability of alternatives, limited acceptance, and stringent regulatory framework are some key constraints that slow down the demand for aptamers. Developed countries such as the United States and Canada are slated to be highly opportune markets for aptamers providers in the long run. 

US Aptamers Market is poised to grow at a sustainable CAGR for the next forecast year.

Market Snapshot - 2024-2031

Global Market Size

USD 1.20 billion

Largest Segment

Nucleic Acid

Fastest Growth

Nucleic Acid

Growth Rate

19.2% CAGR

Global Aptamers Market ($ Bn)
Country Share for North America Region (%)

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Aptamers Market Segmental Analysis

Global Aptamers Market is segmented by Type, Technology, Application, End User, and region. Based on Type, the market is segmented into DNA Aptamers, XNA Aptamers, and RNA Aptamers. Based on Technology, the market is segmented into SELEX, Other Technologies. Based on Application, the market is segmented into Therapeutics Development, Research & Development, Diagnostics, Other Applications. Based on End User, the market is segmented into Pharmaceutical & Biotechnology Companies, Academic & Government Research Institutes, Contract Research Organizations, Other End Users. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & and Africa. 

Analysis by Type 

Nucleic acid aptamers are projected to account for a substantial share of the global aptamers market. High investments in the research and development of novel nucleic acid aptamers by multiple companies around the world are projected to help the dominance of this segment going forward. Increasing approvals of aptamers for use in the treatment of multiple disease indications are also expected to create new business scope for aptamer companies looking to focus on this segment in the future. Use of nucleic acid aptamers in targeted drug delivery is also expected to contribute to the massive share of this segment over the coming years.  

On the other hand, the demand for peptide aptamers is estimated to rise at an impressive pace across the forecast period and beyond. High use of peptide aptamers in therapeutic as well as diagnostic applications is what makes this segment a highly opportune one for any market player. Increasing use of peptide aptamers in the making of novel biochips and other biotechnology products will also create lucrative opportunities for aptamer providers in the long run. The lower toxicity and immunogenicity of peptide aptamers makes them a highly coveted component in medical research. 

Analysis by Application 

Research and development application is forecasted to spearhead the demand for aptamers going forward. Increasing investments in healthcare R&D around the world to combat growing prevalence of chronic diseases and improve healthcare accessibility are helping this segment bring in major revenue for aptamers companies. Rising interest in unique properties of aptamers and growing awareness regarding the benefits of the same are also expected to help this segment maintain its dominance in the future. Developed as well as developing countries are slated to be highly opportune markets for aptamers companies targeting this application segment.  

Meanwhile, the demand for aptamers in therapeutic applications is slated to rise at a notable pace across the forecast period and beyond. High use of aptamers in the preparation of antidotes for various disease indications and growing demand for targeted therapeutics are helping this segment emerge as the fastest growing one in the market. High investments in drug discovery and drug development are also expected to create new opportunities for aptamer companies operating in this segment. Macular degeneration, retinopathy of prematurity, and diabetic retinopathy are some key indications where the use of aptamers as therapeutics is being explored extensively. 

Global Aptamers Market By Type

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Aptamers Market Regional Insights

North America accounted for a dominant share of the global aptamers market. The presence of a strong medical research infrastructure coupled with high prevalence of chronic diseases makes this region an opportune one for all aptamers providers. Growing investments in healthcare research by public as well as private organizations are also expected to help promote the demand for aptamers in North America. Canada and the United States are estimated to remain the most opportune markets for aptamers companies looking to boost their revenue in the North American region going forward. Early adoption of novel healthcare technologies and products will also aid the dominance of this region.

Asia Pacific is estimated to emerge as the fastest expanding market for aptamers around the world. Rising acceptance of aptamer-based products, growing demand for novel diagnostic products, and rising healthcare expenditure are some key factors that are estimated to drive up the demand for aptamers going forward. China, India, and Japan are slated to be the most rewarding markets for aptamers providers as incidence of chronic diseases and geriatric population rises in these countries. Growing investments in healthcare infrastructure development and medical research are also expected to bolster aptamers market growth potential in the future. 

Global Aptamers Market By Region
  • Largest
  • Fastest

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Aptamers Market Dynamics

Drivers

High Demand for Targeted Therapeutics 

  • Growing investments in drug delivery technology development have led to the creation of targeted therapeutics. Acceptance of these targeted therapeutics is increasing rapidly around the world as they eliminate the possibility of unexpected side effects. Aptamers are being used in the creation of these therapeutics thereby driving market growth as well.  

High Use in Diagnostics 

  • The high specificity of aptamers has allowed them to be extensively used in multiple diagnostic applications. The ability of aptamers to detect a range of biomarkers is what helps their application scope in diagnostics. Integration of aptamers with biosensors, lateral flow assays, and ELISA-like platforms for early diagnosis will help market development in the future.  

Restraints 

Short Half-life 

  • Aptamers have a very short half-life ranging from minutes to hours. This short half-life makes it highly difficult to find practical applications for the same. Managing this short half-life and keeping the aptamers characteristics intact without degradation is a challenge that is expected to slow down their demand over the coming years. 

Limited Awareness and Acceptance 

  • The use of aptamers is not as extensive as other biological materials and components as there is a substantial lack of knowledge regarding aptamers. Many researchers, clinicians, and companies are more familiar with antibodies, which is why they favor the use of the same and this limits the demand for aptamers.

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Aptamers Market Competitive Landscape

Investing in the development of specific aptamer-based products for different disease indications should remain the prime focus of all companies. Improving the half-life of aptamers to enhance their practical application scope will also be a major trend to target for all aptamer companies. Collaborations and partnerships are expected to help aptamer providers enhance their business scope on a global level in the future. 

Top Player’s Company Profiles

  • Aptamer Group (UK) 
  • Raptamer Discovery Group (US) 
  • Somalogic, Inc. (US) 
  • Aptamer Sciences, Inc. (US) 
  • Aptagen, LLC  (US) 
  • Maravai Lifesciences (US) 
  • Kaneka Corporation (Japan) 
  • NeoVentures Biotechnology Inc. (Canada) 
  • Aptus Biotech (Spain) 
  • Base Pair Biotechnologies (US) 
  • Amsbio (UK) 
  • Novaptech (France) 
  • Bio-Techne (US) 
  • Aptitude Medical Systems (US) 
  • Raybiotech, Inc. (US) 
  • Alpha Diagnostic International, Inc. (US) 
  • Creative Biolabs (US) 
  • Creative Biogene (US) 
  • Vivonics Inc. (US) 
  • Iba Lifesciences GmbH (Germany) 
  • Aptabharat Innovations Pvt. Ltd (India) 
  • Profacgen (US) 
  • Mediven (Germany) 
  • Pure Biologics SA (Poland) 
  • Oak Biosciences, Inc. (US)

Recent Developments

  • In March 2024, Aptamer Group plc, a leading name in the aptamers business announced the development of a new reagent to improve automated immunohistochemistry (IHC) workflow. Optimer®-Fc tool is the perfect demonstration of how aptamers can be used to develop novel solutions in the healthcare industry.  
  • Back in September 2022, Nutromics, an Australian start-up known for the development of aptamer sensors raised USD 14 million in funding. The medical technology company had plans of using this funding to explore more clinical applications of its novel aptamer-based technologies and products in the future.  
  • In May 2022, Achiko AG, a renowned biotechnology organization announced that it had received a CE Mark approval for its aptamer-based COVID-19 test. The AptameX™ test uses DNA aptamers instead of antibodies to detect COVID-19 and provide a more affordable test alternative for users. 

Aptamers Key Market Trends

  • Chemical Modifications of Aptamers: Aptamer providers should explore and focus on chemical modifications to improve the stability of aptamers. These chemical modifications can help improve the application scope of aptamers by enhancing their pharmacokinetics, target binding, and degradation properties in biological systems. PEGylation (attaching polyethylene glycol) and locked nucleic acid (LNA) modifications are projected to emerge in popularity in the global aptamers market going forward.  
  • Development of Aptamer-based Biosensors: Aptamer companies should focus on the development of aptamer-based biosensors as biotechnology advancements pick up pace around the world. Biosensors that can utilize aptamers as recognition elements for the detection of biomarkers, pathogens, and environmental contaminants are expected to emerge in popularity in the future as demand for portable and mobile detection devices rises. 

Aptamers Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.  

As per SkyQuest analysis, the growing prevalence of chronic diseases and rising investments in aptamer research are projected to drive the demand for aptamers over the coming years. However, limited awareness and short half-life are estimated to slow down the aptamers market growth going forward. North America is estimated to spearhead the global aptamer demand outlook owing to high investments in medical R&D in this region. Development of aptamer-based biosensors and use of chemical modifications to enhance the stability of aptamers will be major trends for market players in the long run. 

Report Metric Details
Market size value in 2022 USD 155 million
Market size value in 2031 USD 677.08 million
Growth Rate 17.80%
Base year 2023
Forecast period 2024-2031
Forecast Unit (Value) USD Million
Segments covered
  • Type
    • DNA Aptamers
  • Technology
    • SELEX, Other Technologies, Research & Development, Others
  • Application
    • Therapeutics Development, Research & Development, Diagnostics, Other Applications
  • End User
    • Pharmaceutical & Biotechnology Companies, Academic & Government Research Institutes, Contract Research Organizations, Other End Users
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Aptamer Group (UK) 
  • Raptamer Discovery Group (US) 
  • Somalogic, Inc. (US) 
  • Aptamer Sciences, Inc. (US) 
  • Aptagen, LLC  (US) 
  • Maravai Lifesciences (US) 
  • Kaneka Corporation (Japan) 
  • NeoVentures Biotechnology Inc. (Canada) 
  • Aptus Biotech (Spain) 
  • Base Pair Biotechnologies (US) 
  • Amsbio (UK) 
  • Novaptech (France) 
  • Bio-Techne (US) 
  • Aptitude Medical Systems (US) 
  • Raybiotech, Inc. (US) 
  • Alpha Diagnostic International, Inc. (US) 
  • Creative Biolabs (US) 
  • Creative Biogene (US) 
  • Vivonics Inc. (US) 
  • Iba Lifesciences GmbH (Germany) 
  • Aptabharat Innovations Pvt. Ltd (India) 
  • Profacgen (US) 
  • Mediven (Germany) 
  • Pure Biologics SA (Poland) 
  • Oak Biosciences, Inc. (US)
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Aptamers Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Aptamers Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Aptamers Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Aptamers Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Aptamers Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Aptamers Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

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FAQs

Global Aptamers Market size was valued at USD 155 million in 2022 and is poised to grow from USD 182.59 million in 2023 to USD 677.08 million by 2031, growing at a CAGR of 17.80% during the forecast period (2024-2031).

Investing in the development of specific aptamer-based products for different disease indications should remain the prime focus of all companies. Improving the half-life of aptamers to enhance their practical application scope will also be a major trend to target for all aptamer companies. Collaborations and partnerships are expected to help aptamer providers enhance their business scope on a global level in the future.  'Aptamer Group (UK) ', 'Raptamer Discovery Group (US) ', 'Somalogic, Inc. (US) ', 'Aptamer Sciences, Inc. (US) ', 'Aptagen, LLC  (US) ', 'Maravai Lifesciences (US) ', 'Kaneka Corporation (Japan) ', 'NeoVentures Biotechnology Inc. (Canada) ', 'Aptus Biotech (Spain) ', 'Base Pair Biotechnologies (US) ', 'Amsbio (UK) ', 'Novaptech (France) ', 'Bio-Techne (US) ', 'Aptitude Medical Systems (US) ', 'Raybiotech, Inc. (US) ', 'Alpha Diagnostic International, Inc. (US) ', 'Creative Biolabs (US) ', 'Creative Biogene (US) ', 'Vivonics Inc. (US) ', 'Iba Lifesciences GmbH (Germany) ', 'Aptabharat Innovations Pvt. Ltd (India) ', 'Profacgen (US) ', 'Mediven (Germany) ', 'Pure Biologics SA (Poland) ', 'Oak Biosciences, Inc. (US)'

Growing investments in drug delivery technology development have led to the creation of targeted therapeutics. Acceptance of these targeted therapeutics is increasing rapidly around the world as they eliminate the possibility of unexpected side effects. Aptamers are being used in the creation of these therapeutics thereby driving market growth as well.  

Chemical Modifications of Aptamers: Aptamer providers should explore and focus on chemical modifications to improve the stability of aptamers. These chemical modifications can help improve the application scope of aptamers by enhancing their pharmacokinetics, target binding, and degradation properties in biological systems. PEGylation (attaching polyethylene glycol) and locked nucleic acid (LNA) modifications are projected to emerge in popularity in the global aptamers market going forward.  

North America accounted for a dominant share of the global aptamers market. The presence of a strong medical research infrastructure coupled with high prevalence of chronic diseases makes this region an opportune one for all aptamers providers. Growing investments in healthcare research by public as well as private organizations are also expected to help promote the demand for aptamers in North America. Canada and the United States are estimated to remain the most opportune markets for aptamers companies looking to boost their revenue in the North American region going forward. Early adoption of novel healthcare technologies and products will also aid the dominance of this region.

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