Breast Cancer Liquid Biopsy Market Size, Share, Growth Analysis, By Technology(Next-generation sequencing (NGS), polymerase chain reaction (PCR), and other techniques), By Biomarker(Circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and extracellular vesicles (EVs)), By End user(Hospitals, diagnostic laboratories, and research centers), By Region - Industry Forecast 2024-2031


Report ID: SQMIG35J2098 | Region: Global | Published Date: February, 2024
Pages: 157 |Tables: 90 |Figures: 76

Breast Cancer Liquid Biopsy Market Insights

Breast Cancer Liquid Biopsy Market size was valued at USD 277 million in 2021 and is poised to grow from USD 417.03 million in 2023 to USD 1746.15 million by 2030, at a CAGR of 22.7% during the forecast period (2023-2030).

The global breast cancer liquid biopsy market has experienced significant growth and innovation in recent years, driven by increasing awareness and adoption of non-invasive diagnostic techniques. The technology's ability to detect tumor-specific genetic mutations, circulating tumor cells, and cell-free DNA provides crucial information for early detection, treatment selection, and monitoring of treatment response. Additionally, ongoing research and development efforts are likely to lead to enhanced sensitivity and specificity of liquid biopsy tests, driving further market expansion.

As the medical community embraces this innovative approach, the global breast cancer liquid biopsy market is expected to experience substantial growth in the coming years. The technology's ability to detect tumor-specific biomarkers, circulating tumor cells (CTCs), and cell-free DNA in blood samples has revolutionized cancer diagnostics and treatment monitoring. Moreover, the market has been fueled by ongoing research and development efforts, collaborations between biotech companies and healthcare institutions, and a rising demand for personalized and targeted therapies for breast cancer patients.

US Breast Cancer Liquid Biopsy Market is poised to grow at a sustainable CAGR for the next forecast year.

Market Snapshot - 2024-2031

Global Market Size

USD 277 million

Largest Segment

Hospitals

Fastest Growth

Hospitals

Growth Rate

22.7% CAGR

Global Breast Cancer Liquid Biopsy Market by region
Country Share for North America (%)

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Breast Cancer Liquid Biopsy Market Segmental Analysis

The global breast cancer liquid biopsy market has been segmented into technology, biomarker, sample, end-user, and region. The technology segment encompasses next-generation sequencing (NGS), polymerase chain reaction (PCR), and other techniques. Biomarker types include circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and extracellular vesicles (EVs). Sample types comprise blood, urine, and other fluids. The end-users consist of hospitals, diagnostic laboratories, and research centers. Geographically, the market is divided into North America, Europe, Asia-Pacific, Latin America, and MEA.

Breast Cancer Liquid Biopsy Market Analysis By Technology

The largest sector in the breast cancer liquid biopsy market is likely to be the cfDNA-based technology, which involves the analysis of fragmented DNA released by cancer cells into the bloodstream.

Meanwhile, the fastest-growing sector in the breast cancer liquid biopsy market is expected to be extracellular vesicle-based technology. Extracellular vesicles, such as exosomes, play a crucial role in intercellular communication, and their cargo often includes genetic material and proteins originating from cancer cells.

Breast Cancer Liquid Biopsy Market Analysis By Biomarker

Circulating tumor DNA (ctDNA) has emerged as the largest and most dominant sector within the global breast cancer liquid biopsy market. ctDNA analysis allows for the detection of specific genetic mutations or alterations in the tumor, providing valuable insights into disease progression and treatment response.

Simultaneously, the fastest-growing sector in the breast cancer liquid biopsy market pertains to extracellular vesicles (EVs). These vesicles hold great promise as potential biomarkers due to their ability to reflect the heterogeneous nature of tumors and their role in intercellular communication.

Global Breast Cancer Liquid Biopsy Market by end-user

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Breast Cancer Liquid Biopsy Market Regional Insights

North America led the way with a strong presence of key market players, advanced healthcare infrastructure, and growing adoption of liquid biopsy technologies. Europe demonstrated significant growth due to increased awareness, supportive government initiatives, and rising research and development activities. The Asia-Pacific region exhibited substantial potential, driven by a large patient pool, expanding healthcare expenditure, and increasing focus on personalized medicine. Latin America and the Middle East/Africa regions also experienced a gradual uptick in liquid biopsy adoption, with improving healthcare facilities and a greater emphasis on cancer diagnostics.

Global Breast Cancer Liquid Biopsy Market by geography
  • Largest
  • Fastest

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Breast Cancer Liquid Biopsy Market Dynamics

Breast Cancer Liquid Biopsy Market Drivers

Increasing Need to Address Breast Cancer

  • The increasing adoption of liquid biopsy techniques is a significant driver in the global breast cancer liquid biopsy market. Compared to traditional tissue biopsies, liquid biopsies allow for the analysis of circulating tumor cells (CTCs), cell-free DNA (cfDNA), and other biomarkers present in blood samples, enabling healthcare professionals to make more informed treatment decisions. Additionally, liquid biopsy has the potential to identify resistance mutations and minimal residual disease, which can aid in personalized treatment strategies, leading to improved patient outcomes and reduced healthcare costs.

Breast Cancer Liquid Biopsy Market Restraints

Lack of Investment for Healthcare Infrastructure

  • Despite the promising benefits, the high cost of liquid biopsy tests is a significant restraint in the global breast cancer liquid biopsy market. The development and implementation of advanced liquid biopsy technologies and assays require substantial investment in research, development, and infrastructure. These costs are often passed on to patients, making the tests less accessible for individuals with limited financial resources or those residing in regions with inadequate healthcare funding. Additionally, reimbursement policies and regulatory challenges associated with liquid biopsy may hinder widespread adoption and limit its availability in certain healthcare settings. Addressing the cost barriers and streamlining reimbursement processes will be essential to ensure equitable access to liquid biopsy for breast cancer patients worldwide.

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Breast Cancer Liquid Biopsy Market Competitive Landscape

The global breast cancer liquid biopsy market was witnessing intense competition among key players. Companies in this space were continuously focusing on technological advancements, strategic collaborations, and product innovations to gain a competitive edge. The market was characterized by a diverse range of liquid biopsy solutions aimed at detecting breast cancer-related biomarkers in a non-invasive manner. Additionally, the growing emphasis on early cancer detection and personalized medicine was fueling the demand for liquid biopsy products, driving further competition and market growth.

Breast Cancer Liquid Biopsy Market Top Player’s Company Profiles

  • Genomic Health (acquired by Exact Sciences) - United States
  • Illumina, Inc. - United States
  • Thermo Fisher Scientific - United States
  • QIAGEN - Germany
  • Myriad Genetics - United States
  • Personal Genome Diagnostics Inc. (PGDx) - United States
  • Bio-Rad Laboratories, Inc. - United States
  • Trovagene, Inc. (acquired by Admera Health) - United States
  • Exosome Diagnostics (acquired by Bio-Techne Corporation) - United States
  • Sysmex Corporation - Japan
  • Natera, Inc. - United States
  • Foundation Medicine (acquired by Roche) - United States
  • GRAIL, Inc. (acquired by Illumina) - United States
  • Menarini Silicon Biosystems - Italy
  • Angle plc - United Kingdom
  • Cynvenio Biosystems, Inc. - United States
  • DiaCarta, Inc. - United States

Breast Cancer Liquid Biopsy Market Recent Developments

  • In January 2021, A partnership between Biodesix and HiberCell to carry out more ELISA research and development as a supplemental diagnostic test was announced.

Breast Cancer Liquid Biopsy Key Market Trends

  • There was a growing emphasis on non-invasive diagnostic methods, such as liquid biopsies, for early detection and monitoring of breast cancer.
  • The adoption of liquid biopsy techniques was increasing due to their potential in providing real-time and actionable insights into the disease's progression and treatment response.
  • Advancements in liquid biopsy technologies and the rising prevalence of breast cancer cases globally were driving market growth. Furthermore, collaborations between biotechnology companies and research institutions were fostering innovative liquid biopsy solutions.

Breast Cancer Liquid Biopsy Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Product types team that Collects, Collates, Co-relates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.

According to our analysis, the global breast cancer liquid biopsy market holds promising future prospects, poised for substantial growth and advancements. The growing interest in precision oncology, which aims to deliver targeted therapies based on a patient's unique genetic profile, has fueled the demand for liquid biopsy tests that provide essential genomic information for treatment decision-making. Liquid biopsies enable the identification of specific genetic mutations and alterations in breast cancer patients. This information allows healthcare professionals to tailor treatment strategies and select targeted therapies for individual patients, driving the demand for liquid biopsy tests.

Report Metric Details
Market size value in 2023 USD 277 million
Market size value in 2031 USD 1746.15 million
Growth Rate 22.7%
Forecast period 2024-2031
Forecast Unit (Value) USD Million
Segments covered
  • Technology
    • Next-generation sequencing (NGS), polymerase chain reaction (PCR), and other techniques
  • Biomarker
    • Circulating tumor cells (CTCs), circulating tumor DNA (ctDNA), and extracellular vesicles (EVs)
  • End user
    • Hospitals, diagnostic laboratories, and research centers
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Genomic Health (acquired by Exact Sciences) - United States
  • Illumina, Inc. - United States
  • Thermo Fisher Scientific - United States
  • QIAGEN - Germany
  • Myriad Genetics - United States
  • Personal Genome Diagnostics Inc. (PGDx) - United States
  • Bio-Rad Laboratories, Inc. - United States
  • Trovagene, Inc. (acquired by Admera Health) - United States
  • Exosome Diagnostics (acquired by Bio-Techne Corporation) - United States
  • Sysmex Corporation - Japan
  • Natera, Inc. - United States
  • Foundation Medicine (acquired by Roche) - United States
  • GRAIL, Inc. (acquired by Illumina) - United States
  • Menarini Silicon Biosystems - Italy
  • Angle plc - United Kingdom
  • Cynvenio Biosystems, Inc. - United States
  • DiaCarta, Inc. - United States
Customization scope

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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Breast Cancer Liquid Biopsy Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Breast Cancer Liquid Biopsy Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Breast Cancer Liquid Biopsy Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Breast Cancer Liquid Biopsy Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Breast Cancer Liquid Biopsy Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Breast Cancer Liquid Biopsy Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Breast Cancer Liquid Biopsy Market size was valued at USD 277 million in 2021 and is poised to grow from USD 417.03 million in 2023 to USD 1746.15 million by 2030, at a CAGR of 22.7% during the forecast period (2023-2030).

The breast cancer liquid biopsy market was witnessing intense competition among key players. Companies in this space were continuously focusing on technological advancements, strategic collaborations, and product innovations to gain a competitive edge. The market was characterized by a diverse range of liquid biopsy solutions aimed at detecting breast cancer-related biomarkers in a non-invasive manner. Additionally, the growing emphasis on early cancer detection and personalized medicine was fueling the demand for liquid biopsy products, driving further competition and market growth. 'Guardant Health - United States', 'Roche Diagnostics - Switzerland', 'Biocept, Inc. - United States', 'Genomic Health (acquired by Exact Sciences) - United States', 'Illumina, Inc. - United States', 'Thermo Fisher Scientific - United States', 'QIAGEN - Germany', 'Myriad Genetics - United States', 'Personal Genome Diagnostics Inc. (PGDx) - United States', 'Bio-Rad Laboratories, Inc. - United States', 'Trovagene, Inc. (acquired by Admera Health) - United States', 'Exosome Diagnostics (acquired by Bio-Techne Corporation) - United States', 'Sysmex Corporation - Japan', 'Natera, Inc. - United States', 'Foundation Medicine (acquired by Roche) - United States', 'GRAIL, Inc. (acquired by Illumina) - United States', 'Menarini Silicon Biosystems - Italy', 'Angle plc - United Kingdom', 'Cynvenio Biosystems, Inc. - United States', 'DiaCarta, Inc. - United States'

The increasing adoption of liquid biopsy techniques is a significant driver in the breast cancer liquid biopsy market. Compared to traditional tissue biopsies, liquid biopsies allow for the analysis of circulating tumor cells (CTCs), cell-free DNA (cfDNA), and other biomarkers present in blood samples, enabling healthcare professionals to make more informed treatment decisions. Additionally, liquid biopsy has the potential to identify resistance mutations and minimal residual disease, which can aid in personalized treatment strategies, leading to improved patient outcomes and reduced healthcare costs.

There was a growing emphasis on non-invasive diagnostic methods, such as liquid biopsies, for early detection and monitoring of breast cancer.

North America led the way with a strong presence of key market players, advanced healthcare infrastructure, and growing adoption of liquid biopsy technologies. Europe demonstrated significant growth due to increased awareness, supportive government initiatives, and rising research and development activities. The Asia-Pacific region exhibited substantial potential, driven by a large patient pool, expanding healthcare expenditure, and increasing focus on personalized medicine. Latin America and the Middle East/Africa regions also experienced a gradual uptick in liquid biopsy adoption, with improving healthcare facilities and a greater emphasis on cancer diagnostics.

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Breast Cancer Liquid Biopsy Market

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