Cancer Cachexia Market Size, Share, Growth Analysis, By Product(Progestogens, Corticosteroids, Combination Therapies, and Others), By Distribution Channels(Hospital Pharmacy, Retail Pharmacy, and Online Pharmacy), By Mechanism of Action(Appetite Stimulators and Weight Loss Stabilizers), By Region - Industry Forecast 2024-2031


Report ID: SQMIG35A2857 | Region: Global | Published Date: March, 2024
Pages: 185 |Tables: 89 |Figures: 72

Cancer Cachexia Market Insights

Global Cancer Cachexia Market size was valued at USD 2.31 Billion in 2022 and is poised to grow from USD 2.42 Billion in 2023 to USD 3.47 Billion by 2031, growing at a CAGR of 4.6% in the forecast period (2024-2031)

According to data released by the National Center for Biotechnology Information (NCBI), the prevalence of cachexia in patients with advanced cancer is estimated at 80.0%. Globally, cachexia accounts for 20.0% of cancer deaths. It is a wasting disorder characterized by weight loss, anorexia, osteoporosis and anemia in patients. It is commonly associated with chronic diseases such as cancer, renal failure, chronic obstructive pulmonary disease (COPD), and HIV. Cancer-induced cachexia is associated with the presence of tumors. According to the Cancer Cachexia Hub, the condition affects an estimated 1.3 million cancer patients in the US. only annually.

Cancer cachexia is a multifaceted disease characterized by involuntary weight loss, muscle wasting, and metabolic abnormalities commonly associated with cancer cachexia market treatment experiences and induces a variety of growth stimulants opportunities impact the event and contribute to the overall cancer cachexia market growth and potential. The global increase in cancer implies a corresponding increase in the prevalence of cancer cachexia, thus increasing the market potential of cancer cachexia. The increasing prevalence of cancer establishes a large patient cohort, promoting opportunities for the development of potential therapies and therapeutic interventions targeting cancer cachexia. Older individuals are more susceptible to cancer, increasing the risk of cancer cachexia. The aging population in many countries highlights huge market opportunities for therapies that address cancer-related challenges including cachexia, thereby driving cancer cachexia into the market.

Market Snapshot - 2024-2031

Global Market Size

USD 2.31 Billion

Largest Segment

Progestogens

Fastest Growth

Corticosteroids

Growth Rate

4.6% CAGR

Global Cancer Cachexia Market ($ Bn)
Country Share for North America Region (%)

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Cancer Cachexia Market Segmental Analysis

In terms of product, the market is segmented into progestogens, corticosteroids, combination therapies, and others. Among distribution channels, the market is segmented into hospital pharmacy, retail pharmacy, and online pharmacy. In terms of mechanism of action, the market is segmented into appetite stimulators and weight loss stabilizers. By region, the global cancer cachexia market is bifurcated into North America, Europe, Asia Pacific, Middle East & Africa, and South America.

Analysis by Product

Progestogens are emerging as an important and important segment in the global cancer cachexia market, using their hormonal effects to prevent cachexia complications. Progestogens are in strong demand due to their potential to control symptoms such as unwanted weight loss and muscle wasting for the solution, and they are positioned as major players in medical scenario have a large share in the global cancer cachexia market, reflecting its reputation and influence.

The corticosteroids segment assumes uncertain importance in the prevention of cancer cachexia and represents a growing segment within the market. Known for their anti-inflammatory properties, corticosteroids are strategically used to target inflammatory pathways that contribute to cachexia and combat the associated tissue loss and constitute a special and distinctive therapeutic class. This segment plays an important role, it contributes immensely to the overall prolongation of the global cancer cachexia market.

Analysis by End-User

The hospital pharmacy segment is expected to account for the largest share of the global cancer cachexia market during the forecast period. The dominance is due to the increased hospitalization of patients with complications associated with cancer and cachexia. Hospital pharmacies are crucial in providing medical services in a hospital setting. They work closely with healthcare teams to ensure that cancer patients with cachexia receive appropriate medication and nutritional support. Hospital pharmacies often stock and dispense specialty drugs for cancer and cachexia. This includes aphrodisiacs, nutritional supplements, and medications to manage symptoms such as pain and nausea.

Furthermore, retail pharmacy and online pharmacy are expected to witness substantial growth by the end of the forecast period due to increasing patient access to home-based care. Retail pharmacies are community health centers and can be accessed by homebound cancer patients. They play an important role in supporting patients and their carers by providing medicines, counseling and educational materials related to the management of cancer and cachexia. Pharmacies offer a variety of over-the-counter medications, including nutritional supplements, which can be useful for cancer patients dealing with cachexia Physicians can provide guidance on how to the effectiveness of these drugs. Ensuring proper drug management is important to manage cancer cachexia. Retail pharmacists can help by counseling patients about the importance of adherence, potential side effects, and appropriate use of prescription medications.

Global Cancer Cachexia Market By Product (%)

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Cancer Cachexia Market Regional Insights

  • The market size in North America is $0.90 billion by 2022. The dominance of this segment is driven by high prevalence of cancer cachexia, increasing awareness of cancer supportive care as well as, availability of adequate reimbursement models in the US. and Canada Greater affordability among patients with results in this sector dominance. Cancer cachexia market report scope includes the regional breakdown, revealing that North America dominated the industry by 2022. Increase in awareness programs related to cancer care is driving the growth of the market regionally in the 19th century. The increasing number of pipeline drugs in Phase III clinical trials is also expected to drive the cancer cachexia market share where these drugs are likely to hit the market in the next few years.
  • The Asia-Pacific is expected to witness an increasing CAGR owing to the increasing number of patients suffering from this disease. In addition to this, market players in this segment are investing heavily in strengthening their supply chains and introducing new drugs. Asia-Pacific is estimated to register the largest market growth during the forecast period. This can be attributed to the presence of many undiagnosed patients and the rapid migration of the population to urban settlements for advanced treatment. Increased disposable income also generally improves patient access to new cancer cachexia treatments. Increased government support for health care and increased awareness of the disease are expected to continue to have a positive impact on market trends
Global Cancer Cachexia Market By Geography
  • Largest
  • Fastest

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Cancer Cachexia Market Dynamics

Drivers

The Chemical Potential in Pipeline to Propel Growth

  • Current treatment options for cachexia in cancer patients are limited to drugs such as progestogens, corticosteroids, and others. These drugs have shown efficacy in the treatment of cancer-induced cachexia, although there are clinical differences in treatment outcomes and no drug candidates are currently approved specifically for this condition. This increases the gap in therapeutic options, which market players are aiming to fill through R&D and the introduction of new drugs in the global market.

Rise in the Incidence of Cancer

  • The growth in the global market will be driven by the increasing incidence of cancer worldwide, as well as increasing funding for R&D to develop new breakthrough therapeutics with certain mechanisms of action. The market growth is favored by increasing focus on cancer palliative care with increasing cancer incidence. Treatment of cancer cachexia includes stimulants and medications. There are several urinary tract drugs in late-stage clinical trials, for the treatment of cancer cachexia, which are expected to be commercialized in the next two to three years. This is also expected to drive market growth.

Restraints

High Costs Associated with Treatment and Aggressive Government Programs to Prevent Development

  • Despite the increasing prevalence of cancer cachexia across the globe, certain factors are restraining the growth of the overall market. Includes high costs associated with cancer and its adjuvant treatments, low drug reimbursement in developing countries. Estimated costs associated with the treatment of cancer patients with cachexia are slightly higher than non-cachexia cancer patients. Thus, the associated high out-of-pocket costs with cancer-induced cachexia and lack of approved products to treat the disease would contribute to the gradual growth of this market during the predicted period.

Limited Understanding of Mechanisms

  • The specific mechanisms underlying cancer cachexia are complex and poorly understood. This lack of clarity hinders the development of targeted treatments and interventions, making it difficult to manage the situation effectively. Cancer cachexia can result from a variety of underlying cancers, each with unique characteristics. The heterogeneity of cancer types and cachexia presents challenges in developing universal therapeutic strategies.

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Cancer Cachexia Market Competitive Landscape

The competitive environment of the Global Cancer Cachexia Market is dynamic and characterized by the presence of a mix of well-established brands, emerging players, and niche producers. Innovation is a key competitive factor. Established organizations within the industry leverage techniques inclusive of product innovation, strategic partnerships, and mergers and acquisitions to strengthen their market position. Additionally, the market is witnessing elevated opposition from local and neighborhood producers supplying cost-powerful options.

Top Player’s Company Profiles

  • Aeterna Zentaris
  • Aphios Corporation
  • Bristol-Myers Squibb Company
  • Pfizer Inc.
  • Helsinn Group
  • Merck KGaA
  • Artelo Biosciences Inc.
  • NGM Biopharmaceuticals
  • Aveo Oncology
  • Aavogen Inc.
  • Green Cross Wellbeing Corporation
  • Cannabics Pharmaceuticals Inc.
  • TCI Peptide Therapeutics
  • Fresenius Kabi
  • Tetra Bio-Pharma
  • Actimed Therapeutics

Recent Developments

  • August 2022: ARTHEx biotech launches ENTRY™, a platform to enhance their drug delivery pipeline including drugs for myotonic dystrophy, cancer cachexia, and osteoporosis by providing intramuscular delivery of antimiRs.
  • June 2022: A team led by the Rutgers Cancer Institute of New Jersey receives a $25 million Cancer Grand Challenge grant for research into cancer cachexia, a debilitating condition that people often experience in the final stages of their cancer.
  • April 2021 - Actimed Therapeutics Ltd. announced a license agreement for S-oxprenolol to Faraday Pharmaceuticals, Inc. Under this agreement, the company is eligible to receive a royalty on any future sales of S-oxprenolol and oxprenolol by Faraday.

Cancer Cachexia Key Market Trends

  • In many cases, traditional approaches to treating patients with single-drug interventions provided limited therapeutic benefit. Also, due to the lack of approved drugs for this condition, healthcare providers have been seen turning to combination therapies to treat illness including both pharmacological and non-pharmacological. Clinical trials show significant improvement in body does not deny (LBM) in treated patients and combination therapies. Thus, such outcomes as the popularity of health professionals increase the acceptability of combination therapy among patient populations and drive the demand for cancer cachexia treatments in the global market.

Cancer Cachexia Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research. Cancer cachexia is a multifaceted disease characterized by involuntary weight loss, muscle wasting, and metabolic abnormalities commonly associated with global cancer cachexia market. Treatment experiences a variety of growth stimulants and it impacts the opportunities and contributes to the growth and potential of the overall global cancer cachexia market. The increasing incidence of cancer worldwide implies a corresponding rise in the prevalence of cancer cachexia, increasing the potential of market. The increasing incidence of cancer establishes a large patient cohort, promoting opportunities for the development of potential therapies and therapeutic interventions targeting cancer cachexia. Older individuals are more susceptible to cancer, increasing the risk of cancer cachexia. The increasing population of elderly populations in many countries highlights the huge market opportunity for therapies addressing cancer-related challenges including cachexia, and thus cancer cachexia to market.

Report Metric Details
Market size value in 2023 USD 2.31 Billion
Market size value in 2031 USD 3.47 Billion
Growth Rate 4.6%
Forecast period 2024-2031
Forecast Unit (Value) USD Billion
Segments covered
  • Product
    • Progestogens, Corticosteroids, Combination Therapies, and Others
  • Distribution Channels
    • Hospital Pharmacy, Retail Pharmacy, and Online Pharmacy
  • Mechanism of Action
    • Appetite Stimulators and Weight Loss Stabilizers
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Aeterna Zentaris
  • Aphios Corporation
  • Bristol-Myers Squibb Company
  • Pfizer Inc.
  • Helsinn Group
  • Merck KGaA
  • Artelo Biosciences Inc.
  • NGM Biopharmaceuticals
  • Aveo Oncology
  • Aavogen Inc.
  • Green Cross Wellbeing Corporation
  • Cannabics Pharmaceuticals Inc.
  • TCI Peptide Therapeutics
  • Fresenius Kabi
  • Tetra Bio-Pharma
  • Actimed Therapeutics
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Cancer Cachexia Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Cancer Cachexia Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Cancer Cachexia Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Cancer Cachexia Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Cancer Cachexia Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Cancer Cachexia Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Cancer Cachexia Market size was valued at USD 2.31 Billion in 2022 and is poised to grow from USD 2.42 Billion in 2023 to USD 3.47 Billion by 2031, growing at a CAGR of 4.6% in the forecast period (2024-2031)

The competitive environment of the Cancer Cachexia Market is dynamic and characterized by the presence of a mix of well-established brands, emerging players, and niche producers. Innovation is a key competitive factor. Established organizations within the industry leverage techniques inclusive of product innovation, strategic partnerships, and mergers and acquisitions to strengthen their market position. Additionally, the market is witnessing elevated opposition from local and neighborhood producers supplying cost-powerful options. 'Aeterna Zentaris', 'Aphios Corporation', 'Bristol-Myers Squibb Company', 'Pfizer Inc.', 'Helsinn Group', 'Merck KGaA', 'Artelo Biosciences Inc.', 'NGM Biopharmaceuticals', 'Aveo Oncology', 'Aavogen Inc.', 'Green Cross Wellbeing Corporation', 'Cannabics Pharmaceuticals Inc.', 'TCI Peptide Therapeutics', 'Fresenius Kabi', 'Tetra Bio-Pharma', 'Actimed Therapeutics'

Current treatment options for cachexia in cancer patients are limited to drugs such as progestogens, corticosteroids, and others. These drugs have shown efficacy in the treatment of cancer-induced cachexia, although there are clinical differences in treatment outcomes and no drug candidates are currently approved specifically for this condition. This increases the gap in therapeutic options, which market players are aiming to fill through R&D and the introduction of new drugs in the market.

In many cases, traditional approaches to treating patients with single-drug interventions provided limited therapeutic benefit. Also, due to the lack of approved drugs for this condition, healthcare providers have been seen turning to combination therapies to treat illness including both pharmacological and non-pharmacological. Clinical trials show significant improvement in body does not deny (LBM) in treated patients and combination therapies. Thus, such outcomes as the popularity of health professionals increase the acceptability of combination therapy among patient populations and drive the demand for cancer cachexia treatments in the market.

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