DNA Synthesis Market Size, Share, Growth Analysis, By Service(Oligonucleotide Synthesis (Standard, Custom), Gene Synthesis (Custom, Gene Library)), By Length(Oligonucleotide Synthesis (< 50 nt, 51-100 nt, 101-150 nt, > 150 nt)), By Application(Research and Development (Oligonucleotide Synthesis [PCR, NGS, CRISPR, Cloning and Mutagenesis), By End Use(Biopharmaceutical and Diagnostics Companies, Academic and Research Institutes, Contract Research Organizations), By Region - Industry Forecast 2025-2032


Report ID: SQMIG35H2185 | Region: Global | Published Date: February, 2024
Pages: 157 |Tables: 88 |Figures: 71

DNA Synthesis Market Insights

DNA Synthesis Market size was valued at USD 3.46 Billion in 2023 and is poised to grow from USD 4.14 Billion in 2024 to USD 17.38 Billion by 2032, growing at a CAGR of 19.63% during the forecast period (2025-2032).

The global DNA synthesis market is experiencing significant growth due to its vital role in various fields such as pharmaceuticals, biotechnology, and genetics research. Researchers and biotech companies are increasingly relying on DNA synthesis services to design and produce custom DNA sequences for a wide range of applications, from drug development to genetic engineering. This market's expansion is driven by the growing demand for synthetic biology tools, the rise of personalized medicine, and the continuous advancements in gene editing technologies.

Moreover, DNA synthesis services enable rapid prototyping and experimentation in the laboratory, fostering innovation and accelerating the pace of scientific discovery. As the biotechnology and healthcare industries continue to evolve, the DNA synthesis market is poised to play a pivotal role in shaping the future of genomics and molecular biology.

US DNA Synthesis Market is poised to grow at a sustainable CAGR for the next forecast year.

Market snapshot - 2025-2032

Global Market Size

USD 2.90 Billion

Largest Segment

Gene Synthesis

Fastest Growth

Gene Synthesis

Growth Rate

19.63% CAGR

Global DNA Synthesis Market ($ Bn)
Country Share for North America Region (%)

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DNA Synthesis Market Segmental Analysis

Global DNA Synthesis Market is segmented by Service, Length, Application, End Use, and region. Based on Service, the market can be segmented into Oligonucleotide Synthesis (Standard, Custom), Gene Synthesis (Custom, Gene Library). Based on Length, the market can be segmented into Oligonucleotide Synthesis (< 50 nt, 51-100 nt, 101-150 nt, > 150 nt), Gene Synthesis (< 500 nt, 501-1000 nt, 1001-1500 nt, 1501-2000 nt, 2001-2500 nt, > 2500 nt). Based on Application, the market is segmented into Research and Development (Oligonucleotide Synthesis [PCR, NGS, CRISPR, Cloning and Mutagenesis, Others], Gene Synthesis [Synthetic Biology, Vaccine Development, Genetic Engineering, Others]), Diagnostics, Therapeutics (RNAi Therapies, Antisense Oligonucleotide-based Therapies, Others). Based on End Use, the market is segmented into Biopharmaceutical and Diagnostics Companies, Academic and Research Institutes, Contract Research Organizations. Based on region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

DNA Synthesis Market Analysis by Service Type

Gene Synthesis is currently the dominating service type in the DNA synthesis market. This is primarily because gene synthesis involves the creation of entire genes, which is crucial for various applications in genetic engineering, synthetic biology, and biotechnology. The ability to design and produce custom genes has broad applications in drug development, vaccine research, and the creation of genetically modified organisms, making it a central service in the field.

However, Oligonucleotide Synthesis is the fastest-growing segment in the DNA synthesis market. This growth can be attributed to its versatility and relevance in areas like genomics, diagnostics, and personalized medicine. Oligonucleotides are shorter DNA or RNA fragments used in a wide range of applications, including PCR, DNA sequencing, and gene editing techniques like CRISPR-Cas9. The rapid growth is driven by the increasing demand for precision medicine, where custom-designed oligonucleotides are essential for tailoring treatments to individual genetic profiles. This trend is likely to continue as genomics and personalized medicine gain prominence in healthcare and research.

DNA Synthesis Market Analysis by Application

Therapeutics is currently the dominating application for DNA synthesis. This dominance can be attributed to the increasing emphasis on precision medicine and the development of personalized therapies. DNA synthesis is crucial for creating custom DNA sequences for gene therapy, vaccine development, and the production of therapeutic proteins. The demand for tailored treatments for various genetic diseases and cancer has propelled therapeutics to the forefront of DNA synthesis applications.

However, Research and Development (R&D) is the fastest growing application for DNA synthesis. The growth can be attributed to the expanding scope of genetic research and synthetic biology projects. R&D teams are using DNA synthesis to create novel genetic constructs, conduct functional genomics studies, and engineer organisms for various purposes. This rapid expansion in R&D is driven by the increasing availability of cost-effective DNA synthesis services, which are enabling researchers to explore new frontiers in genetics, biotechnology, and drug discovery with unprecedented speed and precision.

Global DNA Synthesis Market By Service Type

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DNA Synthesis Market Regional Insights

North America is currently the dominating region in the global DNA synthesis market. This dominance can be attributed to the presence of well-established biotechnology and pharmaceutical industries, strong research and development capabilities, and a higher adoption rate of advanced biotechnological tools and techniques. Additionally, favorable regulatory environments and significant investments in genomics research contribute to North America's leadership in this market.

However, the Asia Pacific is the fastest growing region in the global DNA synthesis market. This rapid growth is driven by factors such as increasing healthcare expenditure, a rising focus on biotechnology research and development, and the growing awareness of personalized medicine. Moreover, the region benefits from a large pool of skilled scientists and researchers, lower operating costs for biotech companies, and a growing trend of outsourcing DNA synthesis services to Asia Pacific countries. These factors collectively contribute to the region's remarkable growth in the DNA synthesis market.

Global DNA Synthesis Market By Region
  • Largest
  • Fastest

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DNA Synthesis Market Dynamics

DNA Synthesis Market Drivers

Advancements in Genetic Engineering Technologies

  • A major key market driver for the DNA synthesis market is the continuous advancements in genetic engineering technologies. These innovations, including CRISPR-Cas9 and other gene-editing techniques, have significantly increased the demand for custom DNA sequences, driving the growth of DNA synthesis services. Researchers and biotech companies require precise and tailored DNA constructs for their experiments and applications, making DNA synthesis a critical component of cutting-edge genetic engineering projects.

DNA Synthesis Market Restraints

Regulatory Challenges

  • One of the major key market restraints in the DNA synthesis industry is the stringent regulatory environment. Stringent regulations and oversight regarding the synthesis and use of genetic materials, particularly in the context of gene editing and biotechnology, can create barriers to market entry and slow down research and development efforts. These regulations are essential for ethical and safety reasons but can pose challenges for businesses in the field.

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DNA Synthesis Market Competitive Landscape

The competitive landscape of the DNA synthesis market is characterized by a diverse array of companies offering a range of synthesis services and technologies. These companies compete based on factors such as the quality and accuracy of synthesized DNA, turnaround times, customization options, and pricing.

Innovation plays a crucial role in this landscape, with companies continually striving to develop advanced synthesis techniques, improve scalability, and enhance the overall efficiency of DNA synthesis processes. Partnerships and collaborations between industry players and academic institutions are also common, facilitating knowledge exchange and the development of cutting-edge solutions.

As the demand for custom DNA sequences expands across various industries, the competitive landscape is expected to remain dynamic, with companies seeking to differentiate themselves through technological advancements and superior service offerings.

DNA Synthesis Market Top Player’s Company Profiles

  • Thermo Fisher Scientific, Inc. (US)
  • Twist Bioscience (US)
  • Bioneer Corporation (South Korea)
  • Eton Bioscience (US)
  • LGC Biosearch Technologies (US)
  • IBA GmbH (Germany)
  • Eurofins Scientific (Luxembourg)
  • Integrated DNA Technologies, Inc. (US)
  • Quintara Biosciences (US)
  • GenScript Biotech Corporation (China)
  • Agilent Technologies (US)
  • Merck KGaA (Germany)
  • Eurogentec (Belgium)
  • Cambio Ltd. (UK)
  • Biomatik (Canada)

DNA Synthesis Market Recent Developments

  • In July 2022, Ribbon Biolabs obtained a U.S. Patent for its technology for synthesizing nucleotide molecules employing a variety of oligonucleotides. For easy access, the method includes a pre-built library of oligonucleotides.
  • In March 2021, Aldevron expanded its manufacturing facility at Madison. At this new facility, the company is scaling up the manufacturing of gene synthesis products and ground-breaking therapies, among others. The company has expanded its product manufacturing and boosted the project scope and scale through this expansion.
  • In February 2021, the "AccuLoader," a novel concept auxiliary device introduced by BIONEER Corporation, is intended to speed up sample preparation by helping to dispense samples and reagents into the proper wells.

DNA Synthesis Key Market Trends

  • Advancements in Gene Editing Technologies: A major market trend in the DNA synthesis industry is the continuous advancement of gene editing technologies, such as CRISPR-Cas9. These technologies are driving demand for custom DNA sequences, as they enable precise genetic modifications for a wide range of applications, including therapeutic development and agriculture. As gene editing tools become more accessible and versatile, the DNA synthesis market is poised for sustained growth, catering to the evolving needs of researchers and biotech companies.

DNA Synthesis Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.

According to the Global DNA synthesis market analysis, the market is witnessing robust growth, driven by the expanding applications of synthetic DNA across diverse industries. Key factors fueling this growth include advancements in biotechnology, increased adoption of personalized medicine, and the growing emphasis on genetic research and gene editing technologies.

Researchers and biotech companies are relying on DNA synthesis services to design and create custom DNA sequences for applications ranging from drug development to gene therapy.

Furthermore, regions like North America and Asia Pacific are emerging as prominent market leaders due to their strong biotechnology sectors and research capabilities.

However, the market faces challenges related to stringent regulatory environments and ethical considerations in gene editing. Balancing innovation with ethical and safety concerns will be essential for sustainable growth.

Overall, the DNA synthesis market is expected to continue expanding as scientific advancements and market demand drive further innovation and investment in this critical sector.

Report Metric Details
Market size value in 2023 USD 3.46 Billion
Market size value in 2032 USD 17.38 Billion
Growth Rate 19.63%
Base year 2024
Forecast period 2025-2032
Forecast Unit (Value) USD Billion
Segments covered
  • Service
    • Oligonucleotide Synthesis (Standard, Custom), Gene Synthesis (Custom, Gene Library)
  • Length
    • Oligonucleotide Synthesis (< 50 nt, 51-100 nt, 101-150 nt, > 150 nt), Gene Synthesis (< 500 nt, 501-1000 nt, 1001-1500 nt, 1501-2000 nt, 2001-2500 nt, > 2500 nt)
  • Application
    • Research and Development (Oligonucleotide Synthesis [PCR, NGS, CRISPR, Cloning and Mutagenesis, Others], Gene Synthesis [Synthetic Biology, Vaccine Development, Genetic Engineering, Others]), Diagnostics, Therapeutics (RNAi Therapies, Antisense Oligonucleotide-based Therapies, Others)
  • End Use
    • Biopharmaceutical and Diagnostics Companies, Academic and Research Institutes, Contract Research Organizations
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Thermo Fisher Scientific, Inc. (US)
  • Twist Bioscience (US)
  • Bioneer Corporation (South Korea)
  • Eton Bioscience (US)
  • LGC Biosearch Technologies (US)
  • IBA GmbH (Germany)
  • Eurofins Scientific (Luxembourg)
  • Integrated DNA Technologies, Inc. (US)
  • Quintara Biosciences (US)
  • GenScript Biotech Corporation (China)
  • Agilent Technologies (US)
  • Merck KGaA (Germany)
  • Eurogentec (Belgium)
  • Cambio Ltd. (UK)
  • Biomatik (Canada)
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on DNA Synthesis Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on DNA Synthesis Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the DNA Synthesis Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the DNA Synthesis Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the DNA Synthesis Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the DNA Synthesis Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

DNA Synthesis Market size was valued at USD 3.46 Billion in 2023 and is poised to grow from USD 4.14 Billion in 2024 to USD 17.38 Billion by 2032, growing at a CAGR of 19.63% during the forecast period (2025-2032).

The competitive landscape of the DNA synthesis market is characterized by a diverse array of companies offering a range of synthesis services and technologies. These companies compete based on factors such as the quality and accuracy of synthesized DNA, turnaround times, customization options, and pricing. 'Thermo Fisher Scientific, Inc. (US)', 'Twist Bioscience (US)', 'Bioneer Corporation (South Korea)', 'Eton Bioscience (US)', 'LGC Biosearch Technologies (US)', 'IBA GmbH (Germany)', 'Eurofins Scientific (Luxembourg)', 'Integrated DNA Technologies, Inc. (US)', 'Quintara Biosciences (US)', 'GenScript Biotech Corporation (China)', 'Agilent Technologies (US)', 'Merck KGaA (Germany)', 'Eurogentec (Belgium)', 'Cambio Ltd. (UK)', 'Biomatik (Canada)'

A major key market driver for the DNA synthesis market is the continuous advancements in genetic engineering technologies. These innovations, including CRISPR-Cas9 and other gene-editing techniques, have significantly increased the demand for custom DNA sequences, driving the growth of DNA synthesis services. Researchers and biotech companies require precise and tailored DNA constructs for their experiments and applications, making DNA synthesis a critical component of cutting-edge genetic engineering projects.

Advancements in Gene Editing Technologies: A major market trend in the DNA synthesis industry is the continuous advancement of gene editing technologies, such as CRISPR-Cas9. These technologies are driving demand for custom DNA sequences, as they enable precise genetic modifications for a wide range of applications, including therapeutic development and agriculture. As gene editing tools become more accessible and versatile, the DNA synthesis market is poised for sustained growth, catering to the evolving needs of researchers and biotech companies.

North America is currently the dominating region in the global DNA synthesis market. This dominance can be attributed to the presence of well-established biotechnology and pharmaceutical industries, strong research and development capabilities, and a higher adoption rate of advanced biotechnological tools and techniques. Additionally, favorable regulatory environments and significant investments in genomics research contribute to North America's leadership in this market.

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