USD 343.85 million
Dravet Syndrome Market Size, Share, Growth Analysis, By Diagnosis(MRI, EEG, SCN1A testing, Others), By Treatment and Management(Seizure medications, A ketogenic diet, Vagus nerve stimulation, Others), By Type of Seizures(Myoclonic Seizures, Atonic Seizures, Absence Seizures, Photosensitive Seizures), By End User(Pharmaceutical Companies, Hospitals, Diagnostic Laboratories, Academic & research institutes), By Region - Industry Forecast 2024-2031
Report ID:
SQMIG35A2815 |
Region:
Global |
Published Date: July, 2024
Pages:
219
|Tables:
92
|Figures:
67
Dravet Syndrome Market Insights
Global Dravet Syndrome Market size was valued at USD 343.85 million in 2022 and is poised to grow from USD 376.17 million in 2023 to USD 771.84 million by 2031, growing at a CAGR of 9.4% in the forecast period (2024-2031).
Dravet’s syndrome, also known as epilepsy, typically presents with recurrent seizures triggered by fever or high temperature. This rare neurological disorder is usually lifelong, affecting individuals from childhood. Dravet syndrome begins in the first year of life and is initially diagnosed in otherwise healthy infants. As the disorder progresses, seizures develop, leading to complications and challenges associated with managing this condition. The unique nature of Dravet syndrome underscores the importance of specialist care and ongoing support for affected individuals and their families.
Market Snapshot - 2024-2031
Global Market Size
Largest Segment
MRI
Fastest Growth
MRI
Growth Rate
9.4% CAGR
Dravet Syndrome Market ($ Mn)
Country Share for North America Region (%)
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Dravet Syndrome Market Segmental Analysis
The global Dravet Syndrome market is segmented based on diagnosis, treatment & management, type of seizures, end user, and region. Based on diagnosis, the market is segmented into MRI, EEG, SCN1A testing, and others. Based on treatment & management, the market is segmented into Seizure medications, A ketogenic diet, Vagus nerve stimulation, and Others. Based on type of seizures, the market is segmented into Myoclonic Seizures, Atonic Seizures, Absence Seizures, Photosensitive Seizures, Partial Seizures, and Others. Based on end user, the market is segmented into Pharmaceutical companies, hospitals, diagnostic laboratories, academic & research institutes, and others. Based on region, the market is segmented into North America, Europe, Asia-Pacific Latin America, and Middle East & Africa.
Analysis by Diagnosis
In 2023, the MRI (Magnetic Resonance Imaging) segment has emerged as the dominant player, commanding the largest share in the Dravet Syndrome surgery product market. This can be attributed to the swift integration of cutting-edge surgical products for Dravet Syndrome and the ready availability of proficient medical personnel. The MRI market is experiencing notable growth propelled by advancements in diagnostic techniques, with innovations such as open MRI, visualization software, and superconducting magnets contributing to its expansion.
On the other hand, Electroencephalography (EEG) plays a pivotal role in the Dravet Syndrome market as a crucial diagnostic tool and monitoring method for individuals affected by this severe form of epilepsy. EEG is instrumental in detecting and characterizing the unique seizure patterns associated with Dravet Syndrome, aiding in the accurate diagnosis of the condition. Continuous or prolonged EEG monitoring is often employed to assess the frequency and severity of seizures, providing valuable insights for healthcare professionals in tailoring treatment plans.
Analysis by End-User
In 2023, the Hospitals segment emerged as the predominant force in the market and is anticipated to maintain its accelerated growth trajectory throughout the forecast period from 2024 to 2031. This dominance can be attributed to the substantial presence of patients receiving treatment for various conditions within hospital settings, equipped with contemporary infrastructure and ample amenities. The majority of individuals seeking medical care, especially those with complex conditions, are catered to within the hospital environment.
Pharmaceutical companies play a crucial role in the Dravet Syndrome market by actively contributing to the research, development, and provision of therapeutic solutions for individuals affected by this rare neurological disorder. These companies invest significantly in the discovery of new drugs and therapies, aiming to address the complex challenges associated with Dravet Syndrome. Their involvement encompasses the entire drug development pipeline, from preclinical research to clinical trials and regulatory approvals. Additionally, pharmaceutical companies engage in the production and distribution of approved medications, ensuring accessibility for patients in need.
Dravet Syndrome Market By Diagnosis
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Dravet Syndrome Market Regional Insights
The market dynamics for a particular industry highlight North America as the predominant region, exerting significant influence, trailed by Europe and Asia Pacific. Key market players are actively directing their efforts towards the advancement of novel drugs and therapies, employing diverse strategies to fortify their market positions. The competitive landscape is marked by a proactive approach among leading entities, who are consistently engaged in research and development activities to introduce innovative solutions. These strategic initiatives not only contribute to the expansion of the market but also enhance the competitive edge of the major players.
The Asia Pacific is poised to experience the most rapid growth in the Dravet syndrome market, propelled by heightened disease prevalence, growing patient awareness, and an expanding array of treatment options. Countries such as India, China, and South Korea are actively prioritizing research and development initiatives, leading to the creation of novel products in the field. Furthermore, these nations are undergoing significant healthcare reforms aimed at enhancing the availability, affordability, and quality of healthcare services. Notably, both China and India are implementing comprehensive reforms to address healthcare challenges and improve the overall health infrastructure, fostering an environment conducive to the growth of the Dravet syndrome market.
Dravet Syndrome Market By Region
- Largest
- Fastest
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Dravet Syndrome Market Dynamics
Drivers
Increasing Heightened Occurrence of Gene Mutations
-
The heightened occurrence of gene mutations, particularly mutations in the SCN1A gene, significantly contributes to the onset of Dravet syndrome in children, with approximately 80-90% of cases linked to mutations in this specific gene. The market's revenue growth is anticipated to be driven by advancements in genetic testing technologies, which have markedly improved the rate of Dravet syndrome diagnosis. The use of advanced genetic testing methods, such as identifying duplications, deletions, mosaicism, and other sophisticated diagnostic approaches, has played a pivotal role in enhancing the accuracy and efficiency of detecting genetic abnormalities associated with Dravet syndrome.
Restraints
Potential Impediments
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The anticipated revenue growth of Dravet syndrome faces potential impediments attributed to various factors. Historically, epilepsy and related seizure disorders have been shrouded in societal stigma, discrimination, misinformation, and fear across many regions globally. The pervasive stigma associated with the ailment could act as a deterrent for individuals seeking treatment, as the fear of being identified with such a condition may discourage them from seeking the necessary medical care.
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Dravet Syndrome Market Competitive Landscape
The competitive environment of the global Dravet Syndrome market is dynamic and characterized by the presence of a mix of well-established brands, emerging players, and niche producers. Innovation is a key competitive factor. Leading brands invest in research and development to introduce new flavors, packaging formats, and health-focused variations to cater to changing consumer preferences. They often set the trends in the industry.
Top Player’s Company Profiles
- GW Pharmaceuticals plc (United Kingdom)
- Zogenix, Inc. (United States)
- Ovid Therapeutics Inc. (United States)
- Biocodex S.A. (France)
- Takeda Pharmaceutical Company Limited (Japan)
- PTC Therapeutics, Inc. (United States)
- Epygenix Therapeutics, Inc. (United States)
- Stoke Therapeutics, Inc. (United States)
- UCB S.A. (Belgium)
- Biscayne Neurotherapeutics, Inc. (United States)
- Anavex Life Sciences Corp. (United States)
- Marinus Pharmaceuticals, Inc. (United States)
- Neurocrine Biosciences, Inc. (United States)
- INSYS Therapeutics, Inc. (United States)
- Otsuka Holdings Co., Ltd. (Japan)
- Aquestive Therapeutics, Inc. (United States)
- Epygenix Therapeutics (United States)
- Eisai Co., Ltd. (Japan)
- Zogenix International Limited (Ireland)
- Tevard Biosciences GmbH (Germany)
Recent Developments
- In February 2024, Encoded Therapeutics Inc., a biotech firm dedicated to genetic medicines targeting severe central nervous system (CNS) disorders, revealed the global development plan for its primary gene therapy candidate, ETX101, aiming to address SCN1A+ Dravet syndrome. Dravet syndrome, the most prevalent form of developmental and epileptic encephalopathy, presents a range of clinical manifestations, such as intractable seizures and neurodevelopmental regression.
- In November 2023, Health Canada greenlights Epidiolex (cannabidiol) for treating seizures in Dravet syndrome, broadening its accessibility for this epilepsy form. Developed by GW Pharmaceuticals (now Jazz Pharmaceuticals), the oral solution gains approval for Lennox-Gastaut syndrome (LGS) and tuberous sclerosis complex (TSC) as well, marking progress in addressing various seizure types.
Dravet Syndrome Key Market Trends
- Recent advancements in regulatory approvals play a pivotal role in propelling the Dravet syndrome industry forward. Notably, the clearance of medications such as Stiripentol (Diacomit) and Epidiolex has significantly contributed to the management and treatment of various symptoms associated with the disorder. These regulatory nods mark crucial milestones in addressing the complex challenges posed by Dravet syndrome. Furthermore, the anticipation of forthcoming regulatory approvals, exemplified by Zogenix's submission of a new drug application (NDA) for its therapeutic candidate ZX008 (Fintepla), is expected to further fuel the rapid expansion of the market.
Dravet Syndrome Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research. Dravet Syndrome, also recognized as Severe Myoclonic Epilepsy of Infancy (SMEI), stands as a rare genetic disorder afflicting roughly one in every 15,700 individuals globally. Typically manifesting in infancy, affected infants grapple with seizures that are often prolonged and challenging to control. As the child progresses in age, the frequency and severity of seizures may intensify, coupled with potential cognitive and behavioral complications. While the prevalence of Dravet Syndrome exhibits regional variations, estimates suggest its impact on approximately one in every 20,000 to 40,000 individuals worldwide. Moreover, the disorder demonstrates a higher incidence in males compared to females, with a male-to-female ratio of around 1.5:1. This information underscores the rarity and gender-related distinctions associated with Dravet Syndrome, emphasizing the need for specialized attention and care for affected individuals.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 343.85 million |
| Market size value in 2031 | USD 771.84 million |
| Growth Rate | 9.4% |
| Base year | 2023 |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Million |
| Segments covered |
|
| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
|
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Dravet Syndrome Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Dravet Syndrome Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Dravet Syndrome Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Dravet Syndrome Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Dravet Syndrome Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Dravet Syndrome Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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