USD 1.36 billion
Epigenetics Market Size, Share, Growth Analysis, By Product type (Reagents, Kits, Instruments, Enzymes), By Technology (DNA Methylation, Histone Methylation, Histone Acetylation, MicroRNA Modification), By Application (Oncology, Cardiovascular Diseases, Metabolic Diseases, Neurological Disorders), By Region - Industry Forecast 2024-2031
Report ID:
SQMIG35H2201 |
Region:
Global |
Published Date: February, 2024
Pages:
157
|Tables:
96
|Figures:
76
Epigenetics Market Insights
Global Epigenetics Market size was valued at USD 1.36 billion in 2022 and is poised to grow from USD 1.6 billion in 2023 to USD 4.7 billion by 2031, growing at a CAGR of 14.8% in the forecast period (2024-2031).
The growth can be attributed to the important role in understanding gene regulation beyond DNA sequencing, aiding in disease research, and improving personalized medicine. Rising investments and finance are expected to boost the growth of the industry during the forecast period.
The prevalence of cancer across the globe is one of the major factors slowing the growth of the market in recent times. For example, according to the PAHO, there are an estimated 20 million new cases of cancer and 10 million deaths from cancer in 2023, and the number of reported cases of cancer each year is expected to be 30 million in the year 2040. Inhibitors of enzymes such as HDM, HMT, DNMT, HAT, and HDAC are used in epigenetic disorders. Other treatments, such as immunotherapy or chemotherapy, can work well. In the future, epigenetic therapy could be considered as the most effective strategy for treating cancer and brain diseases. Thus, the market is expected to grow significantly during the forecast period with high prevalence of cancers along with epigenetics for cancer.
Market snapshot - 2024-2031
Global Market Size
Largest Segment
Reagents
Fastest Growth
Instruments
Growth Rate
14.8% CAGR
Global Epigenetics Market ($ Bn)
Country Share for North America Region (%)
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Epigenetics Market Segmental Analysis
The epigenetics market is segmented into four major segments i.e. by product type, technology, application, and region. Based on type, it is divided into reagents, kits, instruments, enzymes, services. Based on technology, it is bifurcated as DNA methylation, histone methylation, histone acetylation, microrna modification, and other epigenetic modifications. Based on application it is segregated into, oncology, cardiovascular diseases, metabolic diseases, neurological disorders, immunology. Based on region, the market is segmented into North America, Europe, Asia-Pacific, Latin America, Middle East & Africa.
Analysis by Type
The reagent segment dominated the market, accounting for 33.45% of the global revenue in 2023. This segment can be largely attributed to the widespread use of reagents in the study of epigenetic modifications. Reagents play an important role in the study and manipulation of epigenetic mechanisms, involving changes in gene expression without altering the underlying DNA structure. These reagents are important for understanding epigenetic regulation and are used in the potential of research & therapeutic applications. Also, various industry players are providing resources for epigenetics research and studies. For example, Promega Corporation offers kits and reagents for the analysis of DNA methylation, histone modifications, and RNA transcription to support the epigenetic research. Thus, availability of more reagents from key players is also expected to be an important factor for the growth of this segment.
The services segment is expected to follow the highest CAGR of 17.68% during the forecast period. Epigenetic services include a range of offerings including sequencing, analysis and consultation services. Epigenetic analysis includes sophisticated techniques such as ChIP-seq, bisulfite sequencing, and DNA methylation profiling. Many researchers and organizations rely on specialized services to accurately and efficiently perform these complex assessments. The development of high-throughput sequencing technologies and other advanced tools for ongoing epigenetic research requires the development of projects where these technologies can be used to obtain complete and reliable epigenomic data.
Analysis by Application
The oncology segment dominated the market with 69.06% revenue share in 2023. Demand for epigenetics arises from the close association between epigenetic modifications and cancer progression. Epigenetic modifications are important in tumor initiation, progression and metastasis which is examined. Targeting these alterations provides potential avenues for new cancer therapies, including precision therapy. Understanding epigenetic mechanisms in oncology holds promise for the development of new diagnostics and more effective, personalized cancer interventions, and drives demand in the field.
Non-oncology is the fastest growing segment in the market. The non-oncology segment is projected to have the fastest CAGR of 16.30% from 2024 to 2031, due to the growth & development of epigenetics market in non-oncology applications of aging, reproductive health, mental health, drug development, precision medicine, regenerative medicine, materials contributed by a combination of the environmental interventions, chronic inflammatory diseases, and geriatrics.
Global Epigenetics Market By Type (%)
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Epigenetics Market Regional Insights
North America dominated the market, with a share of 38.19% in 2023. The region is growing due to public awareness, improved pharmaceutical facilities and huge investments in R&D. Besides, prevalent chronic diseases and heavy investments by market players in epigenetic research, making it a promising environment for further growth. The presence of major players such as; Elemental Biological Sciences, Inc.; Dovetail Genomics LLC.; Illumina, Inc.; And in the U.S. market, Promega Corporation is expected to support regional expansion. It is expected that the epigenetics market will surge during the forecast period as chronic diseases prevail and increased investment by market players in epigenetics fuels regional growth. For example, epigenetic editing consumes another genomic medicine company, Croma Medicine, Inc.; (Croma) face million invested in US$.
Asia Pacific's epigenetics market is expected to witness the fastest CAGR of 16.71% from 2024 to 2031. This growth of the regional market is expected to be driven by the increasing demand for genome editing technologies and the spread of genetic diseases and infections in countries many such as India and Australia. Also, for epigenetics products and services that attract investment and funding from domestic companies. For example, in August 2023, Epigenic Therapeutics of China raised $32 million in funding. The company develops next-generation gene therapy that uses epigenome design to treat common disorders. Thus, increased investment in such infrastructure is expected to boost regional expansion. The epigenetics market in China is expected to grow during the forecast period, owing to the well-established regulatory framework for the development and commercialization of epigenetically engineered organisms (GMOs).
Global Epigenetics Market By Geography
- Largest
- Fastest
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Epigenetics Market Dynamics
Epigenetics Market Drivers
Rising Prevalence of Cancer and Chronic Diseases
- One of the major drivers of the epigenetics market is the rising prevalence of cancer and other chronic diseases such as cardiovascular disease. Epigenetic modifications such as DNA methylation and histone modifications play an important role in growth and development occurring in these diseases. Significant investments in monetary and medical development have been stimulated e.g. as precision medicine becomes increasingly prominent, epigenetic therapies offer promising potential for personalized therapies, driving the demand for epigenetic products and services.
Rise of Personalized Medicine
- The shift towards personalized medicine, which revolutionizes treatment based on a person’s genomes and genomes, is another important driver of the epigenetics market. Epigenetic biomarkers are increasingly used to develop diagnostic tools and targeted therapies tailored to specific patient profiles. This trend is particularly evident in oncology, where epigenetic agents such as HDAC inhibitors and DNMT inhibitors are gaining momentum. The need for precise diagnostic tools and therapies targeting epigenetic modifications has increased the demand for epigenetics-based research, drug development and diagnostics.
Epigenetics Market Restraints
High Cost of Epigenetic Research and Therapy
- Despite this feasibility, the high cost of epigenetic research and therapeutic development poses a major barrier to market growth. Epigenetic research generally requires advanced technologies and tools such as next-generation sequencing (NGS) and chromatin immunoprecipitation (ChIP), which can be expensive to acquire and operate. This high-cost limits access to epigenetic tools and therapies, especially in developing regions with healthcare budgets.
Limited Understanding and Technical Challenges
- Another major imperative is the still limited understanding of the complexity of epigenetic mechanisms and their interactions with the environment. This knowledge gap presents technical challenges in the development of precise and effective treatments. Furthermore, the difficulty in interpreting epigenetic data often leads to delays in translating research findings into clinically applicable therapies, further hindering the potential growth of the market.
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Epigenetics Market Competitive Landscape
The epigenetics market is characterized by a dynamic and competitive landscape, with a mix of established players and emerging biotech companies driving innovation and growth. Key market participants are increasingly focusing on research and development (R&D) to develop novel epigenetic therapies and diagnostics, capitalizing on the rising interest in personalized medicine and targeted therapies.
Top Player’s Company Profiles in Epigenetics Market
- AbbVie Inc.
- AstraZeneca PLC
- Bayer AG
- BeiGene Ltd.
- Bristol Myers Squibb Company
- Epizyme, Inc.
- GlaxoSmithKline PLC
- Incyte Corporation
- Johnson & Johnson
- Merck & Co., Inc.
- Novartis AG
- Pfizer Inc.
- Regeneron Pharmaceuticals, Inc.
- Roche Holding AG
- Seattle Genetics, Inc.
- Takeda Pharmaceutical Company Limited
- Targovax, Inc.
- Vertex Pharmaceuticals Incorporated
- Vivid Biosciences Inc.
- Zymeworks Inc.
Recent Developments in Epigenetics Market
- In December 2023, Biolabs and Promega expanded their joint efforts to accelerate life science innovation globally by supporting early-stage startups. Waldorf-based Promega GmbH, a subsidiary of the German subsidiary of global life sciences company Promega, provides equipment, services and training to Biolabs Heidelberg.
- In November 2023, QIAGEN and Element Biosciences, Inc. entered into a joint venture. made a collaborative effort. has strategically delivered a complete NGS workflow for the new Element AVITI System.
- In October 2023, Zenith Epigenetics Ltd. acquired 1,000 shares of the stock. and Cencora reached an agreement to commercialize the ZEN-3694 program, an epigenetic approach to enhance the performance of drugs currently marketed for the treatment of cancer.
Epigenetics Key Market Trends
Advances in Epigenetic Editing Technologies:
- A major trend in the epigenetics market is the development of advanced epigenetic editing technologies, such as CRISPR/Cas9-based tools, which allow precise modification of epigenetic marks. This technology allows researchers to modify specific genes without altering the underlying DNA sequence, opening new opportunities to study gene regulation and develop new therapies. Growing adoption of these tools is expected to revolutionize epigenetic research and expand treatment possibilities in areas such as cancer, neurological diseases and autoimmune disorders.
Widespread Use of Epigenetic Biomarkers in Diagnostic Research:
- The use of epigenetic biomarkers for diagnosis is becoming more common. DNA methylation and histone modifications are being studied as reliable biomarkers for early diagnosis, especially in oncology. Liquid biopsies detect epigenetic changes in circulating tumors. DNA (ctDNA) are emerging as non-diagnostic tools, enabling early detection of cancers such as lung and breast cancer. There is increasing emphasis on early detection of cancer and increased demand for accurate diagnosis.
Epigenetics Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
According to SkyQuest analysis, the epigenetics market is experiencing strong growth driven by the rising incidence of cancer and chronic diseases, as well as increasing focus on personalized medicine but the market faces challenges such as rising research costs and a lack of understanding of complex epigenetic mechanisms. As the field of epigenetics keeps adapting, it has amazing potential to transform healthcare by way of permitting extra focused and personalized remedies. Advances within the epigenetic modifying technology and massive use of epigenetic biomarkers for disease diagnosis represent key factors with a purpose to form the future of the market.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 1.36 billion |
| Market size value in 2031 | USD 4.7 billion |
| Growth Rate | 14.8% |
| Base year | 2023 |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
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| Customization scope | Free report customization with purchase. Customization includes:-
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Epigenetics Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Epigenetics Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Epigenetics Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Epigenetics Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Epigenetics Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Epigenetics Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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