USD 1.52 Billion
Gene Synthesis Market Size, Share, Growth Analysis, By Method(Solid-phase Synthesis, Chip-based Synthesis, and PCR-based Enzyme Synthesis), By Services(Antibody DNA Synthesis, Viral DNA Synthesis, and Others), By Application(Gene & Cell Therapy Development, Vaccine Development, and Disease Diagnosis), By End-use(Biotechnology & Pharmaceutical Companies, Academic & Government Research Institutes, and Contract Research Organizations), By Region - Industry Forecast 2024-2031
Report ID:
SQMIG35H2240 |
Region:
Global |
Published Date: February, 2024
Pages:
219
|Tables:
117
|Figures:
77
Gene Synthesis Market Insights
Gene Synthesis Market size was valued at USD 1.76 Billion in 2022 and is poised to grow from USD 2.04 Billion in 2023 to USD 6.75 Billion by 2031, at a CAGR of 16.10 % during the forecast period (2024-2031).
The market's expansion is attributed to factors such as favorable government legislation pertaining to synthetic biology. Investors have become more interested in synthetic biology research in recent years. In 2020, the computer-generated biology sector will receive around USD 8.0 billion from government and commercial investment. The COVID-19 epidemic has benefited the genetic synthesis sector by opening up new avenues for expansion. Researchers are investigating undiscovered possibilities in the field of gene synthesis, which is aiding market expansion in terms of revenue generation. The investigators at the National Institute developing Standards and Technology, for example, have created synthetic SARS-CoV-2 gene segments to aid in the development of precise and trustworthy diagnostic tests for the disease.
Synthetic DNA technical breakthroughs are gaining popularity as a possible way to address concerns about the growing number of new viruses & the potential hazards of a potential global pandemic. The SARS-CoV-2 pandemic, as well as pandemics involving other emerging diseases in the near future, can be addressed fast with the aid of this promising approach for rapidly replicating and analyzing genes of interest.
Targeted therapy has piqued the interest of the biotechnology & pharmaceutical sectors, as well as researchers. It has evolved into an important illness management technique. Targeted therapy in conjunction with immunology and chemotherapy is expected to develop rapidly in the future years. This would create profitable opportunities for existing and fledgling gene synthesis firms.
One of the major issues impeding market expansion is a lack of skilled specialists in the field of gene synthesis and biotechnology, as organizations operating in this industry would require trained and experienced personnel at their facilities. As a result, businesses are forming strategic alliances with universities to provide personnel with online workshops, in-person instruction, and sponsored projects in order to create the proper individuals. This would contribute to the expansion of the gene synthesis market.
Market Snapshot - 2024-2031
Global Market Size
Largest Segment
Antibody DNA Synthesis
Fastest Growth
Antibody DNA Synthesis
Growth Rate
16.1% CAGR
Global Gene Synthesis Market ($ Bn)
Country Share for North America Region (%)
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Gene Synthesis Market Segmental Analysis
The global gene synthesis market is segmented based on method, services, application, end-use, and region. Based on method the market is segmented into Solid-phase Synthesis, Chip-based Synthesis, PCR-based Enzyme Synthesis. In terms of services, the market is segmented into Antibody DNA Synthesis, Viral DNA Synthesis, Others. With respect to categorization by application, the market is segmented into Gene & Cell Therapy Development, Vaccine Development, and Disease Diagnosis. Based on End-use the market is segmented into Biotechnology & Pharmaceutical Companies, Academic & Government Research Institutes, Contract Research Organizations. Regionwise, the market is segmented into North America, Europe, Asia-Pacific, South America, and MEA.
Analysis by Method
The solid-phase synthesis dominated the gene synthesizing market in 2022 with an estimated 35.87% of revenue. It can be used to build modified and canonical polymers of amino acids, particularly RNA or DNA, as this is a popular technology for a variety of applications and research reasons.
The majority of companies currently providing commercial gene synthesis services use a solid-phase synthesis process, utilizing several synthesizing platforms made available by businesses such as Agilent technological advances, Blue Heron Biotech, & Sloning Biotechnology, amongst others.
The PCR-based enzymes segment is predicted to grow at the fastest rate during the projection period. Certain aspects, such as its accuracy, ease of use, and fairly priced technology, are expected to enhance category expansion by 2030. It is an efficient approach for producing the A+T-rich malaria gene.
Furthermore, PCR-based gene production provides a straightforward solution to the problem of producing large amounts of tagged protein for NMR analysis when the gene encoding the protein is difficult or impossible to express efficiently. As a result, the previously mentioned uses of this technology contribute to segment growth.
Analysis by Services
The antibody-based DNA synthesis segment accounted for 60.90% of the market. The existence of various industry competitors providing antibody DNA synthesis services has contributed to the creation of gene market dominance in 2022. industries offer cloning and creation of antibody chain motifs into any vector to research institutions & biotech/pharma industries.
Twist Bioscience Company announced the debut of a high-throughput antibody manufacturing platform in April 2022. Using the antibody production procedure, customers can turn digital DNA (dDNA) sequences into pure IgG antibodies. Codex DNA, Inc. exhibited automated synthetic biology technology to accelerate discovery processes at an antibody engineering and therapeutics conference in Europe in June 2022.
Global Gene Synthesis Market By Services (%)
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Gene Synthesis Market Regional Insights
North America held the highest revenue in 2022. This can be attributed to the presence of many important market participants offering gene synthesis services, as well as the increased interest of large biotechnology and pharmaceutical businesses in gene and cell technologies therapy development, the region's expanding field of synthetic biology, and growing interest in gene production in the molecular biology arena.
Asia Pacific is expected to grow at the quickest rate over the forecast period, owing to increased research activities for the creation of effective treatments, as well as increased interest in the field of synthetic biology research. Furthermore, disease incidence is increasing as a result of lifestyle changes. Improving healthcare infrastructure, the arrival of significant biotechnology organizations, and increased R&D efforts are all likely to contribute to market expansion.
Global Gene Synthesis Market By Geography
- Largest
- Fastest
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Gene Synthesis Market Dynamics
Drivers
Growing Applications in Research and Development
- Gene synthesis plays a crucial role in various fields of research and development, including molecular biology, genetic engineering, drug discovery, and synthetic biology. It enables scientists to study gene function, create genetically modified organisms, develop novel therapeutic agents, and engineer new biological systems. The expanding applications of gene synthesis in research and development activities drive market growth.
Restraints
Ethical and Regulatory Concerns
- The field of gene synthesis raises ethical concerns related to the potential misuse of synthesized genes, such as the creation of dangerous pathogens or organisms. Regulatory frameworks are in place to address these concerns, and adherence to ethical guidelines and regulatory compliance is crucial for the gene synthesis industry. Stringent regulations can sometimes act as a restraint on the market, especially in terms of obtaining approvals and licenses for certain applications.
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Gene Synthesis Market Competitive Landscape
Key market participants are pursuing a number of strategic initiatives, including collaborations, partnerships, & geographical expansions in favorable regions. Companies are launching new items to diversify their product portfolios in the market. ProteoGenix, for example, introduced the XtenCHO Transient CHO Expression System in March 2022.
This product makes recombinant protein manufacturing easier, which speeds up early-stage drug screening. Similarly, Integrated DNA Technology, Inc. announced the release of Alt-R HDR Donor Blocks in February 2022, allowing researchers to change the Homology-directed Repair (HDR) genome in order to produce cures.
Top Player’s Company Profiles
- Eurofins Scientific SE
- ATUM (formerly DNA2.0)
- Integrated DNA Technologies, Inc.
- OriGene Technologies, Inc.
- Bioneer Corporation
- GeneArt (a division of Life Technologies)
- Bio Basic Inc.
- GENEWIZ LLC
- BioCat GmbH
- Eurogentec S.A.
- Biomatik Corporation
- Creative Biogene
- LC Sciences
- Gene Universal Inc.
- Blue Heron Biotech LLC
- Genewell Co., Ltd.
- Quintara Biosciences Inc.
Recent Developments
- In July 2022, for gut microbiome researchers, OraSure Technologies announced the OmniGene Gut RNA and DNA product (OMR-205).
- In April 2022, DNA Script announced an early access program for SYNTAX system users, so that organizations can have early access to the most recent developments in its enzymatic DNA synthesis technology.
Gene Synthesis Key Market Trends
- Increasing Demand for Gene Editing and Gene Therapy: The field of gene editing, particularly with technologies like CRISPR-Cas9, has gained significant attention in recent years. Gene synthesis plays a crucial role in providing custom DNA constructs for gene editing experiments and gene therapy applications. The growing interest in gene editing and gene therapy is driving the demand for gene synthesis services.
- Growing Adoption of Synthetic Biology: Synthetic biology combines engineering principles with biology to design and construct new biological systems. Gene synthesis is a fundamental tool in synthetic biology, enabling researchers to create custom DNA sequences and genetic circuits. The increasing applications of synthetic biology across various sectors, including healthcare, agriculture, and energy, are fueling the demand for gene synthesis.
- Expansion of Personalized Medicine: Personalized medicine aims to provide tailored medical treatments based on an individual's genetic information. Gene synthesis plays a crucial role in producing custom DNA sequences for diagnostic tests, targeted therapies, and precision medicine approaches. The expansion of personalized medicine is driving the need for gene synthesis services.
- Rise of DNA Data Storage: The increasing amount of digital data has led to exploration of alternative data storage methods, such as DNA-based storage. Gene synthesis is used to encode digital data into DNA molecules, which offer high-density and long-term data storage capabilities. The emerging field of DNA data storage presents new opportunities for gene synthesis companies.
Gene Synthesis Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates and Analyzes the Data collected by means of Primary Exploratory Research backed by the robust Secondary Desk research.
According to our gene synthesis market analysis, favorable government legislation pertaining to synthetic biology is the key growth driver. Investors have become more interested in synthetic biology research in recent years. In 2020, the computer-generated biology sector will receive around USD 8.0 billion from government and commercial investment. The COVID-19 epidemic has benefited the genetic synthesis sector by opening up new avenues for expansion. Researchers are investigating undiscovered possibilities in the field of gene synthesis, which is aiding market expansion in terms of revenue generation. The investigators at the National Institute developing Standards and Technology, for example, have created synthetic SARS-CoV-2 gene segments to aid in the development of precise and trustworthy diagnostic tests for the disease.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 1.76 Billion |
| Market size value in 2031 | USD 6.75 Billion |
| Growth Rate | 16.10% |
| Base year | 2023 |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
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| Customization scope | Free report customization with purchase. Customization includes:-
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Gene Synthesis Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Gene Synthesis Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Gene Synthesis Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Gene Synthesis Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Gene Synthesis Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Gene Synthesis Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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