USD 4.77 billion
High-Performance Liquid Chromatography Market Size, Share, Growth Analysis, By Product(Instruments, HPLC Systems, Pumps, Detectors), By Application(Clinical Research Applications, Diagnostic Applications, Forensic Applications, Other Applications), By End - User(Pharmaceutical & Biotechnology Companies, Academic & Research Institutions, Others), By Region - Industry Forecast 2025-2032
Report ID:
SQMIG35H2193 |
Region:
Global |
Published Date: March, 2024
Pages:
219
|Tables:
105
|Figures:
66
High-Performance Liquid Chromatography Market Insights
High-Performance Liquid Chromatography Market size was valued at USD 5.06 Billion in 2023 and is poised to grow from USD 5.36 Billion in 2024 to USD 0 Billion by 2032, growing at a CAGR of 6% during the forecast period (2025-2032).
The market is projected to expand owing to advancements in high-performance liquid chromatography (HPLC) techniques, elevating the reliability and robustness of liquid chromatography operations. Notably, recent HPLC systems offer enhanced features like dual-injection mechanisms, multidimensional capabilities, and intermediate pressure alternatives, bolstering their applicability across diverse research domains. The COVID-19 pandemic has additionally expedited the adoption of HPLC systems, instrumental in developing novel therapeutics, vaccines, and dependable diagnostic techniques for the virus. A case in point is a study published in October 2021 in the Microchemical Journal, unveiling an innovative HPLC-based method for analyzing favipiravir, an emerging antiviral for COVID-19.
Furthermore, considering the mounting apprehensions regarding SARS-CoV-2 mutations, HPLC's epidemiological applications in characterizing viral proteins linked to emerging viral serotypes are poised to gain traction, further boosting market expansion.
Moreover, the recent introduction of various liquid chromatography method development systems and accompanying software is anticipated to simplify usage and heighten HPLC system productivity. A notable instance is the collaboration between Thermo Fisher Scientific, Inc. and ChromSword, resulting in the Thermo Fisher Vanquish HPLC and UHPLC method development system unveiled in August 2021. Likewise, in April 2022, Shimadzu Corporation launched the LabSolutions MD software, specifically designed for HPLC platforms to facilitate analytical method development. These product launches are poised to augment the market presence of HPLC systems and propel market expansion.
US High-Performance Liquid Chromatography Market is poised to grow at a sustainable CAGR for the next forecast year.
Market snapshot - 2024-2031
Global Market Size
Largest Segment
Software Solutions
Fastest Growth
Software Solutions
Growth Rate
6% CAGR
Global High-Performance Liquid Chromatography Market ($ Bn)
Country Share for Asia Pacific Region (%)
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High-Performance Liquid Chromatography Market Segmental Analysis
The global high-performance liquid chromatography market is segmented on the basis of product, application, end – user, region. By product, the market is segmented into Instruments, HPLC systems, pumps, detectors, others, consumables & accessories, columns, reverse-phase HPLC columns, normal-phase HPLC columns, Ion Exchange HPLC columns, size exclusion HPLC columns, other HPLC columns, filters, vials, tubes, others, software. By application, the market is segmented into clinical research applications, diagnostic applications, forensic applications, and other applications. By end – user, the market is segmented into pharmaceutical & biotechnology companies, academic & research institutions, others. By region, the market is segmented into North America, Europe, Latin America, Asia- Pacific, Middle East and Africa.
High-Performance Liquid Chromatography Market Analysis By Applications
In 2021, clinical research applications secured the dominant revenue share, exceeding 35.0%, and are poised to exhibit the swiftest growth rate during the projected period. This growth can be attributed to the burgeoning landscape of clinical trial endeavors, a notable upsurge in biopharmaceutical research and development initiatives, and an escalating demand for high throughput analytical techniques. The technique's allure for clinical research is underscored by its exceptional analytical specificity, rapid runtimes, capacity for multi- and mega-parametric tests, and suitability for thermolabile, polar, and high molecular weight compounds, rendering it a prominent alternative to other analytical methods. These factors are anticipated to substantially propel the adoption of HPLC in clinical research applications.
Diagnostic applications, on the other hand, are galvanized by the technique's pivotal role in identifying and quantifying biomarkers essential for the early detection of chronic diseases. This technique also enhances diagnostic precision by discerning nuances between similar diseases. Moreover, HPLC presents an optimal avenue for metabolite analysis, particularly in assessments related to vitamin D and HbA1c hemoglobin due to its notable reproducibility and low coefficient of variation. As chronic diseases' prevalence rises and the demand for robust diagnostic techniques intensifies, the diagnostic applications of HPLC are predicted to witness rapid expansion over the forecast period.
High-Performance Liquid Chromatography Market Analysis By End - User
In 2021, the pharmaceutical and biotechnology sectors asserted their dominance in the market, capturing a substantial share exceeding 40.0%. HPLC methods are widely employed in these industries for diverse applications such as quality control, ascertaining drug purity, characterizing drug candidates, assessing the stability of active pharmaceutical ingredients, and more. Notably, the segment is projected to experience growth, primarily due to HPLC's seamless compatibility with mass spectrometry, a synergy that elevates detection capabilities and selectivity of the technique. This heightened potential holds significant promise for biopharmaceutical applications, thus acting as a driving force behind market expansion.
In contrast, academic and research institutions are poised to showcase the swiftest growth rate of 7.2% throughout the forecast period. This growth is attributed to escalating government funding directed towards academic research, the increasing integration of analytical instrumentation into academic teaching methodologies, and the pivotal role that academic establishments play in research and development initiatives. Notably, within the U.S., academic institutions contribute to around 50% of basic research endeavors and account for approximately 10% to 15% of the overall research and development landscape. In the financial year 2020, research and development expenditure by these institutions in the U.S. surpassed USD 86.4 billion. Consequently, this segment exhibits a notable propensity for the adoption of HPLC infrastructure, thus emerging as a catalyst for prospective market expansion in the near future.
Global High-Performance Liquid Chromatography Market By Component
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High-Performance Liquid Chromatography Market Regional Insights
In the year 2021, North America held a commanding market share, surpassing 30.0%. This notable prevalence can be attributed to the dynamic expansion of the pharmaceutical industry, substantial investments directed towards research and development endeavors, an escalating demand for clinical diagnostic applications, and the strategic presence of industry leaders like Thermo Fisher Scientific, Inc., Agilent Technologies, Inc., and Bio-Rad Laboratories, Inc. within this geographical sphere. Moreover, the region derives distinct advantages from its heightened scientific awareness and the availability of a skilled workforce, contributing to the escalated adoption and growth of HPLC applications.
Furthermore, North America's dominant position in the HPLC market stems from a confluence of factors. The rapid growth of the pharmaceutical sector has acted as a pivotal driver, spurring the need for precise quality control and analytical methodologies. The region's high research and development spending reflects a commitment to technological advancement and innovation, fostering an environment conducive to the growth of cutting-edge techniques like HPLC. The rising demand for clinical diagnostics, driven by an aging population and a focus on early disease detection, has led to a notable uptick in HPLC's utility in the medical field. The presence of key players enhances the accessibility of advanced technology, promotes research collaboration, and contributes to market expansion.
On the other hand, the Asia Pacific region is positioned for exceptional growth in the forecast period. This projection is primarily grounded in the region's substantial potential for clinical research, bolstered by the availability of a vast patient pool. Countries like China and India, recognized for their substantial production of generics and biosimilars, present promising avenues for HPLC adoption in quality control and testing within these burgeoning pharmaceutical markets. Moreover, the application of HPLC in the analysis of traditional medicinal practices, such as traditional Chinese medicines, offers a novel dimension for market growth, tapping into centuries-old healthcare traditions. As the Asia Pacific region positions itself as a hub for both modern and traditional healthcare advancements, the uptake of HPLC is poised to surge, contributing significantly to the technique's global market expansion.
Global High-Performance Liquid Chromatography Market By Region
- Largest
- Fastest
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High-Performance Liquid Chromatography Market Dynamics
High-Performance Liquid Chromatography Market Drivers
Pharmaceutical and Biopharmaceutical Advancements
- The pharmaceutical and biopharmaceutical sectors' growth drives the demand for high-performance liquid chromatography (HPLC) systems for drug analysis, quality control, and research and development.
Green Chemistry Initiatives
- The emphasis on sustainability and environmental concerns drives the development of green HPLC methods that reduce solvent consumption and waste generation.
High-Performance Liquid Chromatography Market Restraints
Complexity and Skill Requirements
- HPLC techniques require specialized knowledge and skilled operators, limiting accessibility and potentially increasing operational costs.
Competition from Alternative Technologies
- Growing adoption of alternative analytical techniques like mass spectrometry and capillary electrophoresis could hinder HPLC market growth.
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High-Performance Liquid Chromatography Market Competitive Landscape
The competitive landscape of the global High-Performance Liquid Chromatography (HPLC) market is characterized by intense rivalry among prominent players, driven by the increasing demand for accurate and advanced analytical solutions. Established manufacturers and emerging entrants compete to secure market share by offering innovative HPLC systems, columns, detectors, and software platforms.
Leading global players such as Agilent Technologies, Thermo Fisher Scientific, Shimadzu Corporation, and Waters Corporation maintain dominance through their extensive product portfolios, expansive distribution networks, and strong research and development initiatives. These companies continually introduce upgraded systems and technologies, catering to diverse applications within pharmaceuticals, biotechnology, food safety, environmental analysis, and more.
High-Performance Liquid Chromatography Market Top Player’s Company Profiles
- Waters Corporation (USA)
- PerkinElmer, Inc. (USA)
- Bruker Corporation (USA)
- Bio-Rad Laboratories, Inc. (USA)
- JASCO Corporation (Japan)
- Gilson, Inc. (USA)
- Knauer GmbH (Germany)
High-Performance Liquid Chromatography Market Recent Developments
- In February 2024, Waters (WAT) launched the HPLC CONNECT software to integrate its high and ultra-performance liquid chromatography (HPLC/UPLC) systems and multi-angle light-scattering instruments (MALS) into an all-in-one software platform.
- In 2023, Agilent Technologies launched New HPLC System for Cannabis Analysis.
- In 2023, Shimadzu Corporation Introduces New HPLC System for Metabolomics.
High-Performance Liquid Chromatography Key Market Trends
- Hyphenated Techniques: The integration of HPLC with mass spectrometry (LC-MS) and other hyphenated technologies enhances analytical capabilities, providing more comprehensive information and improving sensitivity.
- Green and Sustainable HPLC: The development of environmentally friendly methods that reduce solvent consumption and waste generation aligns with sustainability goals and regulatory requirements.
High-Performance Liquid Chromatography Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Product types team that Collects, Collates, Co-relates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
According to our global high-performance liquid chromatography market analysis, the global High-Performance Liquid Chromatography (HPLC) market is poised for sustained growth driven by expanding applications across pharmaceuticals, biotechnology, clinical diagnostics, and environmental analysis. Key factors include continuous technological advancements, integration of hyphenated techniques, and the pursuit of sustainability through green chemistry practices. Established industry leaders like Agilent Technologies, Thermo Fisher Scientific, and Shimadzu Corporation are competing through product innovation and strategic collaborations, maintaining their dominance. Moreover, emerging players are seizing opportunities within niche markets and technological niches. While challenges such as high costs and regulatory complexities persist, trends like automation and miniaturization are shaping the future of HPLC. As industries demand accurate, sensitive, and efficient analytical solutions, the global HPLC market is positioned for dynamic expansion, further solidifying its significance in scientific research, quality control, and diagnostics.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 4.77 billion |
| Market size value in 2030 | USD 8.06 billion |
| Growth Rate | 6% |
| Base year | 2023 |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
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| Customization scope | Free report customization with purchase. Customization includes:-
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To get a free trial access to our platform which is a one stop solution for all your data requirements for quicker decision making. This platform allows you to compare markets, competitors who are prominent in the market, and mega trends that are influencing the dynamics in the market. Also, get access to detailed SkyQuest exclusive matrix.
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on High-Performance Liquid Chromatography Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on High-Performance Liquid Chromatography Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the High-Performance Liquid Chromatography Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the High-Performance Liquid Chromatography Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the High-Performance Liquid Chromatography Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the High-Performance Liquid Chromatography Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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