Hormone Replacement Therapy (HRT) Market Size, Share, and Growth Analysis

Global Hormone Replacement Therapy (HRT) Market

Hormone Replacement Therapy (HRT) Market By Therapy Type (Estrogen and Combinations Replacement Therapy, Thyroid Hormone Replacement Therapy), By Indication (Menopause, Hypothyroidism), By Region - Industry Forecast 2025-2032


Report ID: SQMIG35F2010 | Region: Global | Published Date: December, 2024
Pages: 165 |Tables: 92 |Figures: 77

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Hormone Replacement Therapy (HRT) Market Insights

Global Hormone Replacement Therapy (HRT) Market size was valued at USD 28.97 billion in 2023 and is poised to grow from USD 31.23 billion in 2024 to USD 56.35 billion by 2032, growing at a CAGR of 7.8% during the forecast period (2025-2032). 

Hormone replacement therapy has been successfully utilized for many years to treat menopause-related illnesses in women. As a result, hot flashes, osteoporosis risks, and other menopause symptoms have decreased as well. These treatments are also fueling the market's expansion due to the rise in other hormone-related illnesses targeted at various age groups that impact both women and men. As a result, during the forecast period, diseases such thyroid disorders, growth deficiencies, and others are also expected to accelerate market expansion globally.

The availability of long-acting hGH products and factors including the increased prevalence of target diseases are driving the expansion of the hormone replacement therapy (HRT) market. The American Thyroid Association estimates that 12% of Americans will experience thyroid disease at some point in their lives. Additionally, it stated that about 20 million Americans suffer from thyroid disease. Numerous investigations revealed that individuals receiving HRT treatment probably had a low risk of COVID-19 infection and mortality.

US Hormone Replacement Therapy (HRT) Market is poised to grow at a sustainable CAGR for the next forecast year.

Market snapshot - 2025-2032

Global Market Size

USD 28.97 billion

Largest Segment

growth hormone replacement therapy

Fastest Growth

growth hormone replacement therapy

Growth Rate

7.8% CAGR

Global Hormone Replacement Therapy (HRT) Market, 2021-2028 ($ Bn)
Country Share for Asia Pacific Region- 2021 (%)

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Hormone Replacement Therapy (HRT) Market Segments Analysis

Global Hormone Replacement Therapy (HRT) Market is segmented by therapy type, indication, route of administration, distribution channel and region. Based on therapy type, the market is segmented into estrogen and combinations replacement therapy, thyroid hormone replacement therapy, growth hormone replacement therapy and testosterone hormone replacement therapy. Based on indication, the market is segmented into menopause, hypothyroidism, male hypogonadism and growth hormone deficiency. Based on route of administration, the market is segmented into oral, transdermal and parenteral. Based on distribution channel, the market is segmented into hospitals pharmacies, retail pharmacies & drug stores and online pharmacies. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.  

Hormone Replacement Therapy (HRT) Market Analysis by Therapy Type

The increased adoption of these better therapies, the availability of these medications in a variety of formulations, and the increased awareness of menopause symptoms around the world, Estrogen and combined hormone replacement therapy have dominated the market expansion. During the foreseeable period, growth hormone replacement therapy is anticipated to support a significant CAGR. Growing demand for growth hormone therapies, which are safe and effective in comparison with low risks such as fluid retention, peripheral edema, carpal tunnel syndrome, glucose intolerance, and others, is due to an increase in the prevalence of growth hormone deficiencies in important nations. Additionally, this therapy segment's medications generate higher market revenues.

Hormone Replacement Therapy (HRT) Market Analysis by Route of Administration

Due to the launch of innovative gel formation therapies that hold more effectively without any risk in the treatment, the transdermal segment is predicted to experience a comparatively high CAGR throughout the forecast period. For instance, Gedeon Richter reported that it has begun selling Lenzetto (a transdermal spray containing estradiol) in the United Kingdom. The spray is used to treat and manage the symptoms of oestrogen insufficiency in postmenopausal women. During the forecast period, the parenteral segment is anticipated to have the lowest CAGR.

Global Hormone Replacement Therapy (HRT) Market By Therapy type, 2021 (%)

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Hormone Replacement Therapy (HRT) Market Regional Insights

The region with the largest market share is Asia Pacific, which is expected to hold the position over the forecast period. This is related to the fact that the region is home to major consumers like China and India. Reliance Industries Limited reports that the demand for PE increased by 4%. Growing demand from sectors like packaging and infrastructure & construction is what's fueling market expansion in this nation.

The second-largest portion of the global market was accounted for by Europe. Growing demand from automotive industry for this polymer is anticipated to add to the high market revenue in the region. Due to its qualities including electric insulation, corrosion inhibition, strong heat resistance, and low density, Polyethylene (PE) is the most desired polymer among the several others used in Europe.

Global Hormone Replacement Therapy (HRT) Market By Geography, 2021-2028
  • Largest
  • Fastest

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Hormone Replacement Therapy (HRT) Market Dynamics

Hormone Replacement Therapy (HRT) Market Driver

  • The treatments are essential for a variety of patients, including those with growth hormone shortages, menopausal issues in women, and hypogonadism in the elderly. The medication is offered in many different formats, including skin and buccal patches, injections, tablets, and others. Due to the increased use of these goods around the world, producers are concentrating on creating cutting-edge medication delivery systems, like transdermal estrogen patches and vaginal estrogen pills. In keeping with the safety concerns, they are also concentrating on the introduction of low dose estrogen therapy rather than high dose estrogen therapy. Another development in the global market embraced by the major players is the introduction of gel-based formulation for estrogen patches and other products.

Hormone Replacement Therapy (HRT) Market Restraint 

  • Some factors are having a detrimental effect on market expansion. There are many different formulations of treatments, including patches, gel, capsules, and injections. The market expansion, however, could be hampered by potential side effects of these products, such as an increase in cholesterol levels, blood clots, bloating, swelling, and others.
  • The expansion of the market is also anticipated to be hampered by the negative effects of testosterone replacement therapy, such as benign prostatic hyperplasia, obstructive sleep apnea, and prostate cancer. Additionally, the US FDA has expressed concern regarding the approved indication and the rising occurrences of cardiovascular risks connected with the testosterone replacement therapy products due to the growth in cardiovascular diseases in patients receiving testosterone replacement therapy.

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Hormone Replacement Therapy (HRT) Market Competitive Landscape

Due to their extensive global product portfolios, Novo Nordisk A/S and Pfizer Inc. are the primary players currently leading this market. Due to the success of its well-known pharmaceutical product, Norditropin, Novo Nordisk dominates the market in terms of revenue. During the projected period, it is estimated that significant product upscaling will fuel the market's expansion.

Top Players in the Global Hormone Replacement Therapy Market 

  • Eli Lilly and Company 
  • Pfizer Inc. 
  • Novo Nordisk A/S 
  • AbbVie Inc. 
  • TherapeuticsMD Inc. 
  • Bayer AG 
  • Mylan N.V. (now part of Viatris) 
  • Allergan plc (now part of AbbVie) 
  • Sanofi S.A. 
  • Ferring Pharmaceuticals 
  • Merck & Co. Inc. 
  • Johnson & Johnson 
  • Ipsen S.A. 
  • GlaxoSmithKline plc (GSK) 
  • Amgen Inc. 

Hormone Replacement Therapy (HRT) Market Recent Developments

  • In January 2022, the European Commission gave Ascendis Pharma A/S permission to sell its medication SKYTROFA for the treatment of growth hormone abnormalities in children and adolescents. This medicine is the first once-weekly therapy for pediatric growth hormone insufficiency.
  • In January 2022, the Ministry of Health, Labor and Welfare of Japan gave the go-ahead for Pfizer, Inc. and OPKO Health, Inc. to commercialize NGENLA for the treatment of growth hormone disorders. With a once-weekly treatment frequency, this product is the next-generation long-acting growth hormone injection.

Hormone Replacement Therapy (HRT) Key Market Trends

Hormone Replacement Therapy (HRT) Market SkyQuest Analysis

SkyQuest's ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates and Analyses the Data collected by means of Primary Exploratory Research backed by the robust Secondary Desk research.

According to our analysis, the global hormone replacement therapy (HRT) market is segmented based on therapy type, indication, route of administration, and region. The increased adoption of these better therapies, the availability of these medications in a variety of formulations, and the increased awareness of menopause symptoms around the world, Estrogen and combined hormone replacement therapy have dominated the market expansion. Due to the launch of innovative gel formation therapies that hold more effectively without any risk in the treatment, the transdermal segment is predicted to experience a comparatively high CAGR throughout the forecast period. The region with the largest market share is Asia Pacific, which is expected to hold the position for the duration of the forecast.

Report Metric Details
Market size value in 2023 USD 28.97 billion
Market size value in 2032 USD 56.35 billion
Growth Rate 7.8%
Base year 2024
Forecast period 2025-2032
Forecast Unit (Value) USD Billion
Segments covered
  • Therapy Type
    • Estrogen and Combinations Replacement Therapy, Thyroid Hormone Replacement Therapy, Growth Hormone Replacement Therapy, Testosterone Hormone Replacement Therapy
  • Indication
    • Menopause, Hypothyroidism, Male Hypogonadism, Growth Hormone Deficiency
  • Route Of Administration
    • Oral,, Transdermal, Parenteral
  • Distribution Channel
    • Hospitals Pharmacies, Retail Pharmacies & Drug Stores, Online Pharmacies
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Eli Lilly and Company 
  • Pfizer Inc. 
  • Novo Nordisk A/S 
  • AbbVie Inc. 
  • TherapeuticsMD Inc. 
  • Bayer AG 
  • Mylan N.V. (now part of Viatris) 
  • Allergan plc (now part of AbbVie) 
  • Sanofi S.A. 
  • Ferring Pharmaceuticals 
  • Merck & Co. Inc. 
  • Johnson & Johnson 
  • Ipsen S.A. 
  • GlaxoSmithKline plc (GSK) 
  • Amgen Inc. 
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Hormone Replacement Therapy (HRT) Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Hormone Replacement Therapy (HRT) Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Hormone Replacement Therapy (HRT) Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Hormone Replacement Therapy (HRT) Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Hormone Replacement Therapy (HRT) Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Hormone Replacement Therapy (HRT) Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

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FAQs

Global Hormone Replacement Therapy (HRT) Market size was valued at USD 28.97 billion in 2023 and is poised to grow from USD 31.23 billion in 2024 to USD 56.35 billion by 2032, growing at a CAGR of 7.8% during the forecast period (2025-2032). 

Due to their extensive global product portfolios, Novo Nordisk A/S and Pfizer Inc. are the primary players currently leading this market. Due to the success of its well-known pharmaceutical product, Norditropin, Novo Nordisk dominates the market in terms of revenue. During the projected period, it is estimated that significant product upscaling will fuel the market's expansion. 'Eli Lilly and Company ', 'Pfizer Inc. ', 'Novo Nordisk A/S ', 'AbbVie Inc. ', 'TherapeuticsMD Inc. ', 'Bayer AG ', 'Mylan N.V. (now part of Viatris) ', 'Allergan plc (now part of AbbVie) ', 'Sanofi S.A. ', 'Ferring Pharmaceuticals ', 'Merck & Co. Inc. ', 'Johnson & Johnson ', 'Ipsen S.A. ', 'GlaxoSmithKline plc (GSK) ', 'Amgen Inc. '

The treatments are essential for a variety of patients, including those with growth hormone shortages, menopausal issues in women, and hypogonadism in the elderly. The medication is offered in many different formats, including skin and buccal patches, injections, tablets, and others. Due to the increased use of these goods around the world, producers are concentrating on creating cutting-edge medication delivery systems, like transdermal estrogen patches and vaginal estrogen pills. In keeping with the safety concerns, they are also concentrating on the introduction of low dose estrogen therapy rather than high dose estrogen therapy. Another development in the global market embraced by the major players is the introduction of gel-based formulation for estrogen patches and other products.

Pharmaceutical companies are continually being driven to provide new cutting-edge medications to the worldwide market by the surge in unmet demand for hormone replacement therapy in emerging nations and the increased awareness of the treatment of hormone problems. Additionally, the growth in menopause and illnesses associated with hormone shortage in important nations has prompted manufacturers to introduce new goods, such as combination treatment products, in place of the long-acting parenteral medications that were formerly taken on a daily basis.

The region with the largest market share is Asia Pacific, which is expected to hold the position over the forecast period. This is related to the fact that the region is home to major consumers like China and India. Reliance Industries Limited reports that the demand for PE increased by 4%. Growing demand from sectors like packaging and infrastructure & construction is what's fueling market expansion in this nation.

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Global Hormone Replacement Therapy (HRT) Market
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Report ID: SQMIG35F2010

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