USD 1.34 billion
In Situ Hybridization ISH Market Size, Share, Growth Analysis, By Technology(Fluorescent In Situ Hybridization (FISH), Chromogenic In Situ Hybridization (CISH)), By Product(Instruments, Kits & Probes, Software, Service), By Application(Cancer, Cytogenetics, Developmental Biology, Infectious Diseases), By Region - Industry Forecast 2024-2031
Report ID:
SQSG35J2010 |
Region:
Global |
Published Date: April, 2024
Pages:
278
|Tables:
92
|Figures:
76
In Situ Hybridization ISH Market Insights
In Situ Hybridization ISH Market size was valued at USD 1.34 billion in 2022 and is poised to grow from USD 1.44 billion in 2023 to USD 2.42 billion by 2031, growing at a CAGR of 6.9% in the forecast period (2024-2031).
Nucleic acids can be found and localized in cells, histological sections, and other biological samples using the molecular biology technique known as in-situ hybridization (ISH). It has many uses in molecular diagnosis, gene editing, and recombinant DNA technology because it enables scientists to observe how nucleic acids are distributed throughout the genome of the target organism. Due to ISH's high sensitivity, accurate localization, and effective quantification of sample nucleic acids, as well as its use in more and more fields including molecular biology, immunology, developmental biology, hematopathology, and phylogenetic analysis, the market is growing in terms of revenue.
Researchers have been able to learn more about disease prognosis, drug discovery and development, and the use of biomarkers through the detection of mRNA molecules and the study of the functional state of cells, among other major applications. Several research institutions and organizations have engaged in extensive R&D over the past few years to create a technology that can analyze the molecular profiles of individual cells. For instance, Proximity Ligation in situ Hybridization, an in situ hybridization method developed by Bio-protocol. The method is praised for its high performance, affordability, rapid multiplexing, and ease of use.
US In Situ Hybridization ISH Market is poised to grow at a sustainable CAGR for the next forecast year.
Market Snapshot - 2024-2031
Global Market Size
Largest Segment
Fluorescent In Situ Hybridization (FISH)
Fastest Growth
Chromogenic In Situ Hybridization (CISH)
Growth Rate
6.9% CAGR
Global In Situ Hybridization ISH Market, 2024-2031 ($ Bn)
Country Share for North America Region- 2024 (%)
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In Situ Hybridization ISH Market Segmental Analysis
Global in situ hybridization (ISH) market is segmented based on the Technology, Product, Application, and region. Based on the Technology, the Global In Situ Hybridization (ISH) Market is segmented as FISH, and CISH. Based on the Product, the Global In Situ Hybridization ISH Market is segmented as Instruments, Kits & Probes, Software, and Service. Based on Application, the Global In Situ Hybridization ISH Market is segmented as Cancer, Cytogenetics, Developmental Biology, Infectious Diseases, and Other. Based on Region it is categorized into North America, Europe, Asia-Pacific, Latin America, and MEA.
In Situ Hybridization ISH Market Analysis by Technology
Based on the Technology, the in situ hybridization ISH market is bifurcated into FISH, and CISH. The market share that belongs to FISH is the largest. This can be attributed to the numerous applications, such as the ability to diagnose congenital illnesses like Down syndrome and Edwards syndrome. The use of FISH technology has increased as a result of the rising prevalence and diagnosis of these diseases, which is anticipated to hasten market expansion. Due to its advantages over FISH in terms of cost, dependability, and practicality, the CISH market segment has also amassed a sizeable portion of in situ hybridization over time. With the help of the technology, conventional peroxidase reactions can detect copies of the HER-2/neu oncogene. The CISH market is expected to grow at a faster rate than average over the course of the forecast period due to rising acceptance of CISH technology for HPV genotyping on cervical smears.
In Situ Hybridization ISH Market Analysis by Product
Based on Product the in situ hybridization ish market is segmented into Instruments, Kits & Probes, Software, and Service. The Instruments category held the most market share. The growing networks of diagnostic and research laboratories are responsible for the rising demand for instruments. In situ hybridization is also expected to grow as a result of an increase in the number of strategic initiatives taken by the players to diversify their product offerings. As an illustration, in April 2021, Bio-Techne Corporation declared that it would release new DNA scope assays and RNAscope technology in the commercial market. It will be used to identify changes in DNA's copy number and structural makeup. Launches of such new products would support market expansion.
In Situ Hybridization ISH Market Analysis by Application
Based on Application the in situ hybridization ISH market is segmented into Cancer, Cytogenetics, Developmental Biology, Infectious Diseases, and Other. The Cancer category held the most market share. It is anticipated that the growth will be fueled by an increase in the incidence rate of cancer cases. Around 1.9 million new cases of cancer are anticipated to be reported in the US in 2021, according to data released by the American Cancer Society. The need for in situ hybridization techniques for quick and accurate diagnosis is high due to the increase in cancer cases. Leading causes of cancer include an aging population, an increase in unhealthy lifestyles, poor health conditions, and the environment. Numerous organizations conduct research and support the advancement of cancer treatments. For instance, the grant program for cancer research at the American Institute for Cancer Research funded roughly 110 million USD in 2020–21.
Global In Situ Hybridization ISH Market By Technology, 2024(%)
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In Situ Hybridization ISH Market Regional Insights
North America is expected to control the in situ hybridization (ISH) market share. The presence of a sizable number of market participants and the regional government's encouragement of research projects are both responsible for the region's growth. Throughout the forecast period, the region will continue to dominate due to high healthcare costs and strict FDA and Health Canada regulations. The most patents are in the North American market, while the Asia-Pacific market has a higher marginal increase than other markets. Health Canada-funded research institutions and projects are likely to have a small but positive impact on the market. The market is anticipated to grow the fastest in Asia Pacific during the anticipated period. Over the course of the forecast period, increasing the involvement of local authorities in R&D is anticipated to be the main market driver. In the Asia Pacific region, China and India have the two fastest-growing economies.
Global In Situ Hybridization ISH Market By Geography, 2024-2031
- Largest
- Fastest
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In Situ Hybridization ISH Market Dynamics
In Situ Hybridization ISH Market Driver
- Over the past few years, there has been an increase in cancer cases worldwide. Recurrent genomic abnormalities have been identified as potential initiating factors for a number of cancers as a result of extensive research on human diseases over the past few decades. The integration of cytogenetic assays, such as ISH, with DNA FISH and IHC completes the set of in situ tools available to researchers for the creation, discovery, and application of next-generation diagnostic techniques. A special insight into the interaction between cancer cells and the tumour microenvironment while the cancer is progressing is provided by direct imaging of gene expression in situ at the RNA level. According to GLOBOCAN, there were 43.8 million cancer patients worldwide in 2018 and 9.6 million cancer-related deaths. In 2018, there were roughly 18.1 million new cases reported. By 2040, the number of cases of cancer could rise to 29.5 million, with a mortality rate of 16.5 million. Furthermore, compared to earlier estimates of 400,000, the incidence of haemophilia has tripled to reach 1,125,000, according to research from McMaster University (Canada). France, Canada, Italy, Australia, the UK, and New Zealand are the nation’s most severely impacted. The market will probably benefit from this increase.
- Increased use of the in-situ hybridization technique in research facilities and laboratories for conducting pharmacodynamics studies and diagnosing chromosomal abnormalities, infectious diseases, and cancer are factors driving growth. Other factors driving growth include rising healthcare spending, the high prevalence of chronic diseases, such as Alzheimer's disease and cancer.
In Situ Hybridization ISH Market Restraint
- Short-lived fluorophore molecules and difficulties in identifying individuals in samples with few copies of nucleic acids are two major factors anticipated to significantly slow market revenue growth. Since the signal's fluorescence rapidly decreases with passing time, FISH is a time-dependent detection method. Additionally, FISH is less sensitive for the detection of unbalanced translocations and is unable to detect low clonal cells for minimal residual disease following cancer treatment. In-situ hybridization's lower sensitivity compared to immunohistochemistry, the relatively low number of false-positive results, and sample contamination during PCR are some additional factors limiting market revenue growth. In-situ hybridization has become less popular as a commercial technique for diagnosing diseases with low titer loads of pathogens due to its high detection threshold.
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In Situ Hybridization ISH Market Competitive Landscape
Global in situ hybridization (ISH) market is highly competitive and somewhat fragmented. To maintain a competitive edge, the major industry participants are continually implementing various growth strategies. Innovations, mergers, and acquisitions, collaborations and partnerships are adopted by these players to thrive in the competitive market. In order to provide industries with the most effective and economical solutions, the major market players are also continually concentrating on R&D.
In Situ Hybridization ISH Market Top Player's Company Profiles
- Abbott Laboratories
- Agilent Technologies
- Bio-Rad Laboratories, Inc.
- Danaher Corporation
- F. Hoffmann-La Roche AG
- GE Healthcare
- Merck KGaA
- Oxford Gene Technology
- PerkinElmer, Inc.
- Qiagen N.V.
- Sakura Finetek USA, Inc.
- Sigma-Aldrich Corporation
- Thermo Fisher Scientific, Inc.
- Exiqon A/S
- Bio-Techne Corporation
- Abillionova Corporation
- Advanced Cell Diagnostics
- BioGenex Laboratories, Inc.
- Leica Biosystems Nussloch GmbH
- ZytoVision GmbH
In Situ Hybridization ISH Market Recent Developments
- In May 2022, Abbott has launched the HBsAg Next Qualitative Assay for early detection of the Hepatitis B virus (HBV) in India. Early identification of HBV infections not only helps in preventing or delaying progression of advanced liver diseases but also reduces the risk of transmission.
- In April 2022, Thermo Fisher Scientific on Thursday launched its new research and development and engineering facility in Hyderabad.
In Situ Hybridization ISH Key Market Trends
- With the goal of increasing the sensitivity of in situ hybridization methods, the market is observing developments at a highly encouraging rate. In situ hybridization techniques' range of applications have recently expanded thanks to innovations like strand displacement amplification and molecular beacons. Due to their ability to identify targets with low copy numbers of nucleic acids in samples, some of these cutting-edge techniques have significantly expanded the utility of in situ hybridization in the fields of research and diagnostic pathology.
In Situ Hybridization ISH Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected utilizing Primary Exploratory Research backed by the robust Secondary Desk research.
According to our Global In Situ Hybridization (ISH) Market Analysis, in terms of Technology, The market share that belongs to FISH is the largest. This can be attributed to the numerous applications, such as the ability to diagnose congenital illnesses like Down syndrome and Edwards syndrome. In terms of application, The Cancer category held the most market share. It is anticipated that the growth will be fueled by an increase in the incidence rate of cancer cases.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 1.34 billion |
| Market size value in 2031 | USD 2.42 billion |
| Growth Rate | 6.9% |
| Base year | 2023 |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
|
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on In Situ Hybridization ISH Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on In Situ Hybridization ISH Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the In Situ Hybridization ISH Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the In Situ Hybridization ISH Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the In Situ Hybridization ISH Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the In Situ Hybridization ISH Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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