USD 951.72 million
Inhaled Nitric Oxide Market Size, Share, Growth Analysis, By Product type(Gas and Delivery System), By Application(Neonatal Respiratory Treatment, Asthma & COPD, Acute Respiratory Distress Syndrome and Malaria Treatment), By End User(Near-term & Pre-term Infants PPHN, Children & Adult ARDS, and Other Diseases), By Region - Industry Forecast 2025-2032
Report ID:
SQMIG35I2329 |
Region:
Global |
Published Date: April, 2024
Pages:
218
|Tables:
88
|Figures:
75
Inhaled Nitric Oxide Market Insights
Inhaled Nitric Oxide Market size was valued at USD 1027 Million in 2023 and is poised to grow from USD 1108.65 Million in 2024 to USD 1894.52 Million by 2032, growing at a CAGR of 7.95% during the forecast period (2025-2032).
A crucial chemical for maintaining multiorgan survival and vascular homeostasis is nitric oxide. Its antibacterial qualities, respiratory issues, and cardio-cerebrovascular benefits are all beneficial. Inhaled nitric oxide improves ventilation-perfusion matching and arterial oxygenation by expanding the circulating pulmonary arteries, which increases blood flow to the ventilated areas of the lungs. Supplementing with nitric oxide is a common practice among athletes and fitness enthusiasts. By improving blood flow, oxygen delivery, and muscle nutrient absorption, it improves exercise performance. The primary focus of the major industry actors is the pipeline connections that facilitate the transport of nitrogen, argon, hydrogen, carbon monoxide, and oxygen. The major actors in many end-user industries, such as the pharmaceutical and healthcare sectors, watch over the distribution process.
The increase in end-users around the world is anticipated to propel the inhaled nitric oxide market worldwide. The market for inhaled nitric oxide is expected to rise due to several factors, including rising awareness and acceptance of nitric oxide's use in the healthcare sector, rising rates of cardiovascular and respiratory disorders, technical developments, and research and clinical studies. The market is expected to grow as more medical professionals become aware of the benefits of inhaled nitric oxide and its usage rises. The need for inhaled nitric oxide will rise due to the increasing number of respiratory and cardiovascular diseases, as it will aid in therapy.
Market snapshot - 2025-2032
Global Market Size
Largest Segment
Gas
Fastest Growth
Delivery System
Growth Rate
7.95% CAGR
Global Inhaled Nitric Oxide Market ($ Bn)
Country Share for North America (%)
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Inhaled Nitric Oxide Market Segmental Analysis
The global inhaled nitric oxide market is segmented based on product type, application type, end user type and regional type. In terms of product type, the market is segmented into gas and delivery system. Based on application type, the market is bifurcated into neonatal respiratory treatment, asthma & COPD, acute respiratory distress syndrome and malaria treatment. Based on end user type, the market is bifurcated into near-term & pre-term Infants PPHN, children & adult ARDS and other diseases. Based on region, the market is segmented into North America, Europe, Asia Pacific, Central & South America and Middle East & Africa. Throughout the projected period, product types are anticipated to develop at the fastest rates.
Inhaled Nitric Oxide Market Analysis by Product
As per categorization by product type, the market is classified into gas and delivery system. Among these, gas types earned the largest share and continue to dominate the market. There is a lot of innovation and use of inhaled nitric oxide in the medical industry in the global market. Gas-inhaled nitric oxide is being used more and more to treat ailments such as respiratory distress syndrome and pulmonary hypertension, demonstrating its effectiveness and adaptability. Its expanding significance in clinical settings is shown by its use in neonatal care and as an adjuvant therapy for respiratory disorders. This pattern points to a bright future for inhaled nitric oxide as a treatment choice, which will fuel market growth.
Due to many variables, the inhaled nitric oxide delivery system is expected to develop at the fastest rate in the worldwide inhaled nitric oxide market. There is an increasing need for efficient treatment alternatives due to the rising prevalence of respiratory conditions such pulmonary hypertension and chronic obstructive pulmonary disease (COPD). The inhalation of nitric oxide propels the market's expansion at an accelerated pace since it provides a focused and effective delivery route with low systemic adverse effects and a speedy commencement of action.
Inhaled Nitric Oxide Market Analysis by Application
The global inhaled nitric oxide market is changing due to advancements in malaria and respiratory illnesses. Inhaled nitric oxide has shown promise in respiratory care as an additional therapy for both chronic obstructive pulmonary disease (COPD) and acute respiratory distress syndrome (ARDS). It can lower pulmonary hypertension and increase oxygenation. Furthermore, new studies demonstrate how effective it is in preventing lung problems linked to malaria, providing a fresh method of treating this potentially fatal form of illness and broadening its use in the treatment of infectious diseases.
Acute respiratory distress syndrome (ARDS) and asthma and COPD are expected to have the quickest rates of growth in the global inhaled nitric oxide market as of the pressing demand for efficient treatment solutions and the rising prevalence of these conditions. As a treatment for these ailments, inhaled nitric oxide exhibits encouraging outcomes, providing bronchodilatory effects in COPD and asthma and enhancing oxygenation and pulmonary vascular resistance in acute respiratory distress syndrome (ARDS). The need for inhaled nitric oxide in the treatment of various respiratory illnesses is anticipated to rise sharply, propelling market expansion, as personalized medicine and tailored therapies gain more attention.
Global Inhaled Nitric Oxide Market By Product (%)
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Inhaled Nitric Oxide Market Regional Insights
Throughout the anticipated period, North America is anticipated to maintain its prominent position in the global inhaled nitric oxide market. This is since there are recognized organizations for research and development as well as a modern healthcare infrastructure. To deliver inhaled nitric oxide therapy, North America offers sophisticated healthcare facilities, including clinics and hospitals, as well as the knowledge and resources to do so. During the anticipated period, the inhaled nitric oxide market is expected to grow at the quickest rate in Europe. This is due to the presence of significant regional players, continuing research, and clinical trials regarding the safety and effectiveness of inhaled nitric oxide. In Europe, pulmonary hypertension is a prevalent ailment that impacts many people.
Regional analyses show that the Middle East and Africa (MEA), Latin America, and Asia Pacific are the three regions where the global inhaled nitric oxide market is growing at the fastest rate. The growing healthcare infrastructure and increased incidence of respiratory illnesses in Asia Pacific are fueling market expansion. With rising awareness and healthcare spending, Latin America is seeing a rise in the use of cutting-edge medical treatments, such as inhaled nitric oxide. Due to the high prevalence of respiratory ailments in the MEA region, there is a growing demand for effective respiratory treatments, which has resulted in a quick uptake of inhaled nitric oxide therapies.
Global Inhaled Nitric Oxide Market By Geography
- Largest
- Fastest
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Inhaled Nitric Oxide Market Dynamics
Inhaled Nitric Oxide Market Drivers
To Combat Against Respiratory Diseases
- The market for inhaled nitric oxide is significantly driven by the rising prevalence of respiratory illnesses. The need for inhaled nitric oxide as a therapy option is anticipated to increase if these disorders continue to impact many people globally. Exposure to air pollution, cigarette smoke, and occupational risks are examples of environmental contaminants that can have a substantial impact on respiratory health and raise the chance of acquiring respiratory disorders. The ageing population's weakening immune systems and inherent changes in lung function make them more vulnerable to respiratory diseases. It is anticipated that the prevalence of respiratory illnesses would increase as the world's population ages.
Advancement in Respiratory Care
- Innovations in respiratory treatment are a major factor propelling the worldwide inhaled nitric oxide market. Acute respiratory distress syndrome (ARDS), chronic obstructive pulmonary disease (COPD), and pulmonary hypertension are among the disorders for which there is an increasing need for novel treatments as medical knowledge of respiratory diseases expands and technology advances. As inhaled nitric oxide can widen pulmonary arteries, enhance oxygenation, and lower pulmonary hypertension, it is a viable treatment option that is gaining traction and propelling the market.
Inhaled Nitric Oxide Market Restraints
Supervisory Hurdles
- Numerous regulatory requirements had to be met by the product. Pharmaceutical items must be standardised and approved, which is an expensive and time-consuming process that restricts the market and delays the creation of new medications and their release. Pricing and reimbursement for inhaled nitric oxide can provide significant regulatory challenges in certain healthcare systems. To guarantee payment for their goods and entry into the market, businesses must lead price talks with payers and navigate the intricate world of health technology assessment.
Availability of Nitric Oxide Gas Being Limited
- The restricted supply of nitric oxide gas is a major obstacle to the growth of the worldwide inhaled nitric oxide industry. Nitric oxide is not easily accessible in big quantities and must undergo intricate chemical reactions to be manufactured. Furthermore, the manufacture of high-purity nitric oxide gas necessitates specialised infrastructure and knowledge, which limits the available supply. Due to the restricted scalability of inhaled nitric oxide therapy, this limited availability might impede market growth and cause price swings, especially in areas with strong demand and inadequate supply infrastructure.
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Inhaled Nitric Oxide Market Competitive Landscape
Several significant worldwide firms vying for market supremacy define the competitive landscape of the global inhaled nitric oxide market. To improve their position in the industry, major firms like Novoteris, Linde plc, Praxair Inc., Mallinckrodt Pharmaceuticals, and Air Liquide are actively working on new products, forming strategic alliances, and merging. To take advantage of the rising demand for inhaled nitric oxide therapy globally, these companies are concentrating on broadening their product offerings and geographic reach.
Inhaled Nitric Oxide Market Top Player’s Company Profiles
- Perma Pure LLC (US)
- Merck KGaA (Germany)
- HALMA PLC (UK)
- Pieris Pharmaceuticals (US)
- Air Liquide Healthcare (France)
- Bellerophan Therapeutics Inc. (US)
- Mallinckrodt Pharmaceuticals (Novoteris) (US)
- Matheson Tri-Gas Inc. (US)
- BOC Healthcare (UK)
- Vero Biotech (US)
- Nu-Med Plus Inc. (US)
- Praxair Distribution Inc. (US)
- LINDE PLC (UK)
- Beyond Air
- Taiyo Nippon Sanso Corporation
- Praxair, Inc. (now part of Linde plc)
- Novoteris, LLC
- Nu-Med Plus, Inc.
Inhaled Nitric Oxide Market Recent Developments
- In February 2023, Vero Biotech announced that Genosyl, a second-generation anesthetic, has been approved by the FDA for use in functional rooms. Second-generation Genosyl was produced by Vero Biotech specifically for the administration of inhaled nitric oxide. The FDA just approved a third-generation gadget; however, it hasn't been tested using rebreathing anesthesia yet.
- In May 2023, the safety survey of the 10 mg dry powder amount safety cohort from the most recent multi-center placebo-organized phase 2a study was announced by Pieris Pharmaceuticals, Inc., a clinical-stage biotechnology company that advances new biotherapeutics throughout its proprietary Anticalin technology stage for a respiratory disorder and cancer.
- In August 2022, A two-year USD 600,000 Small Business Innovation Research (SBIR) grant was given to Zylo Therapeutics Inc. to help develop the company's unique topical medication that releases nitric oxide for the treatment of onychomycosis. The National Institute of Allergy and Infectious Diseases, a branch of the National Institutes of Health (NIH), is the sponsor of the funding.
Inhaled Nitric Oxide Key Market Trends
- Growing Impact of Asthma and COPD: Among the most prevalent respiratory illnesses impacting the public are asthma and COPD, both of which can be fatal and impair a patient's daily ability to breathe. Chronic asthma is a disorder that causes the lungs' air passageways to expand and constrict, which results in attacks of dyspnea, bronchospasm, and reversible airflow blockage. A significant increase in cigarette usage exacerbates the symptoms of COPD and asthma. Furthermore, because of increased industrialization, there are now more occurrences of COPD and asthma, which could drive up demand for inhaled nitric oxide during the projection period.
- Government and Non-Government Initiatives: The total revenue is rising because of an increase in the number of projects that both governmental and non-governmental organizations are launching. For example, the NACP programme of the CDC funded patient education in 2021. Initiatives like these are probably going to raise awareness of asthma, which in turn will encourage people to use inhaled nitric oxide to relieve their symptoms. This will propel the expansion of the market under study in the area.
Inhaled Nitric Oxide Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
As per SkyQuest analysis, the rising incidence of respiratory diseases is driving the global market for inhaled nitric oxide, and as these illnesses continue to have an influence on people's lives, so too will demand for this therapy. The market for inhaled nitric oxide is expected to rise as improvements in respiratory care continue to make it a viable therapy choice for ailments like pulmonary hypertension, chronic obstructive pulmonary disease, and acute respiratory distress syndrome (ARDS). Inhaled nitric oxide products have regulatory obstacles, such as the necessity for standardization and approval, which hinder innovation and postpone the goods' entry into the market. Furthermore, the scalability of inhaled nitric oxide therapy is hampered by limited availability of nitric oxide gas due to intricate manufacturing procedures and specialized infrastructure, which may hinder market expansion.
Major worldwide players contending for market supremacy, including Novoteris, Linde plc, Praxair Inc., Mallinckrodt Pharmaceuticals, and Air Liquide, form the competitive landscape of the global inhaled nitric oxide market. To strengthen their position in the market and take advantage of the increasing demand for inhaled nitric oxide therapy globally, these firms priorities innovation, strategic alliances, and mergers. They also place a strong emphasis on expanding their product portfolios and geographic reach. By encouraging the use of inhaled nitric oxide to reduce symptoms, government and non-government programmes to promote knowledge of asthma—like the CDC's NACP programme sponsoring patient education in 2021—are generating more income and may even spur market expansion in the area.
| Report Metric | Details |
|---|---|
| Market size value in 2023 | USD 1027 Million |
| Market size value in 2032 | USD 1894.52 Million |
| Growth Rate | 7.95% |
| Base year | 2024 |
| Forecast period | 2025-2032 |
| Forecast Unit (Value) | USD Million |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
|
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Inhaled Nitric Oxide Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Inhaled Nitric Oxide Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Inhaled Nitric Oxide Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Inhaled Nitric Oxide Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Inhaled Nitric Oxide Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Inhaled Nitric Oxide Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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