Label Free Detection Market Size, Share, Growth Analysis, By Product (Consumables, Instruments), By Technology (Bio-Layer Interferometry, Differential Scanning Calorimetry), By Application, By End-User, By Region - Industry Forecast 2025-2032


Report ID: SQMIG35I2221 | Region: Global | Published Date: June, 2021
Pages: 242 |Tables: 126 |Figures: 77

Label Free Detection Market Insights

Label Free Detection Market size was valued at USD 1.4 Billion in 2023 and is poised to grow from USD 1.52 Billion in 2024 to USD 2.71 Billion by 2032, growing at a CAGR of 8.5% during the forecast period (2025-2032).

Integrated systems known as "label-free detection systems" are used to examine bimolecular interactions without the use of auto-fluorescence effects or labels. A quick and real-time approach to the discovery of new drugs is provided by these systems. Biochemical and cell-based assay detection are the most common applications for label-free detection.

The label-free detection market is being driven by a number of significant factors, one of which is the introduction of technologically advanced products. Over the period from 2021 to 2028, there will also be an increase in the number of academic-industrial partnerships supporting drug discovery programs, which will also contribute to the expansion of the global market.

The market expansion is also being aided by the rapid increase in funding for research and the high sensitivity of label-free technologies. One of the major contributors for the expansion of the label-free detection market is the expanding scope of pharmaceutical and biotechnology-related research and development activities. Over the forecast period, high industry growth will also be assured by the growing awareness among end-users about the benefits of using label-free detection methods.

US Label Free Detection Market  is poised to grow at a sustainable CAGR for the next forecast year.

Market snapshot - 2024-2031

Global Market Size

USD 1.5 billion

Largest Segment

Consumables

Fastest Growth

Consumables

Growth Rate

8.2% CAGR

Global Global Label Free Detection Market ($ Mn)
Country Share for North America Region (%)

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Label Free Detection Market Segmental Analysis

Global Label Free Detection Market is segmented by product, technology, application, end-user and region. Based on product, the market is segmented into consumables and instruments. Based on technology, the market is segmented into bio-layer interferometry, differential scanning calorimetry, isothermal titration calorimetry, surface plasmon resonance, mass spectrometry and other LFD technologies. Based on application, the market is segmented into binding kinetics, binding thermodynamics, endogenous receptor detection, hit confirmation, lead generation and other. Based on end-user, the market is segmented into pharmaceutical & biotechnology companies, academic & research institutes and contract research organizations. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.

Label Free Detection Market Analysis by Product Type

Based on the product type, Consumables accounted for the majority of the market in 2021. In addition, the same market segment is anticipated to grow at the highest CAGR between 2021 and 2028 as a result of ongoing advancements in label-free detection technologies and rising government investments in the biopharmaceutical and biotechnology sectors.

Label Free Detection Market Analysis by Technology

On the basis of technology, the surface plasmon resonance technology sector accounted for the majority of the market in 2021. In addition, the same market segment is anticipated to exhibit the highest CAGR from 2021 to 2028. This growth is due to the technology's high sensitivity and extensive use in regulating specificity, affinity, and kinetic parameters during macromolecule binding.

Global Label Free Detection Market By product type (%)

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Label Free Detection Market Regional Insights

North America held the largest global label free detection market share in 2021. The extensive funding provided by the region's government and the proliferation of technological advancements have contributed to the region's expansion.

The growth of the Label-Free Detection Market in North America is further fueled by the rise in the prevalence of diseases, extensive partnerships between pharmaceutical companies and academic institutions, the presence of numerous pharmaceutical and biotechnological companies employing label-free techniques like bio-layer interferometry (BLI) and surface plasmon resonance (SPR), and the development of drug discovery programs.

Asia-Pacific region is estimated to be the region with the fastest CAGR rate over the forecast period. The increased awareness of label-free techniques like bio-layer interferometry (BLI) and surface plasmon resonance (SPR) and the rise in government initiatives to improve healthcare infrastructure are two contributing factors to this expansion.The growth of the Label-Free Detection Market in the Asia-Pacific region is further fueled by the skyrocketing investments made in biotechnology and drug discovery.

Global Label Free Detection Market By Geography
  • Largest
  • Fastest

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Label Free Detection Market Dynamics

Label Free Detection Market Drivers

Evolution of Life Science to Bolster Demand for Label Free Detection Market

  • Companies in the market should have access to a variety of development opportunities as a result of the growth of life sciences research in emerging markets and the development of more sensitive non-marker technologies. Some market drivers for label-free detection include the introduction of cutting-edge technology products and the rise in the use of efficient product delivery. The market for label-free detection presents numerous opportunities for investigating molecule-interaction interactions without labels' quenching effects. Label-free technologies, which are relatively new to the well-established field of high throughput screening, offer opportunities for probing biomolecular interactions without the spatial interference, autofluorescence, or quenching effects of labels.

Label Free Detection Market Restraints

High Cost Associated with Instruments might Hinder Market Growth

  • The market expansion is significantly hampered by the instruments needed for label-free detection's high cost. Another significant factor preventing the global label free detection market from growing to its full potential is a lack of awareness of the advantages of label free detection.

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Label Free Detection Market Competitive Landscape

Global label free detection market is fragmented in nature as new players are entering the market. These players are adopting numerous strategies such as product launches, joint ventures, mergers and acquisitions, and research and development to gain an edge over their competitors and stay ahead in the competition.

Label Free Detection Market Top Player’s Company Profile

  • Agilent Technologies, Inc. (USA) 
  • Danaher Corporation (USA) 
  • PerkinElmer, Inc. (USA) 
  • GE Healthcare (USA) 
  • Thermo Fisher Scientific Inc. (USA) 
  • Bio-Rad Laboratories, Inc. (USA) 
  • F. Hoffmann-La Roche AG (Switzerland) 
  • Horiba, Ltd. (Japan) 
  • Malvern Panalytical Ltd. (UK) 
  • Bruker Corporation (USA) 
  • Waters Corporation (USA) 
  • Shimadzu Corporation (Japan) 
  • Corning Incorporated (USA) 
  • Hitachi High-Tech Corporation (Japan) 
  • Molecular Devices, LLC (USA) 
  • Sartorius AG (Germany) 
  • BiOptix Analytical LLC (USA) 
  • Attana AB (Sweden) 
  • XanTec Bioanalytics GmbH (Germany)

Label Free Detection Market Recent Developments

  • In January 2022, Waters Corporation announced that it has acquired the technology assets and intellectual property rights of Megadalton Solutions, Inc., an early-stage developer of Charge Detection Mass Spectrometry (CDMS) technology and services.
  • In August 2021, Agilent Technologies Inc. announced the launch of the Agilent Seahorse XF Pro Analyzer, featuring new pharma-oriented workflow solutions incorporating advanced experimental design and analysis tools.

Label Free Detection Key Market Trends

  • Collaborations will Provide Market to Flourish during Forecast Period: The Label-Free Detection market is expanding due to technological advancements and collaborations. Bio-layer interferometry (BLI) and surface plasmon resonance (SPR) are two commonly used methods for label-free detection. The first commercially available optically based, single-mode benchtop model for cell-based and biochemical assays is the novel Corning® Epic® BT. Corning's benchtop label-free detection system has a packed design, a lower price point, clear data collection software, and a comprehensive microplate investigation using charge-coupled device (CCD) wavelength shift discovery. The novel system improves assay capabilities and makes it simple for researchers, including academic labs, to access the Epic technology. Advinus Therapeutics was chosen by Corning as a partner for preparing the Corning Epic® label-free detection technology for sale in India. Advinus was able to use Epic for its own drug discovery programs and for providing assay development and screening services to clients in India and around the world thanks to their partnership. The Label-Free Detection Market is expanding thanks to collaborations and technological advancements of this kind.

Label Free Detection Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected using Primary Exploratory Research backed by robust Secondary Desk research.

According to our global label free detection market analysis, the market is experiencing huge progress and development due to investment in R&D activities. Research programs and collaborations will bring forth more opportunities for players. Investing in product portfolio expansion and product launches will allow players to capture a larger consumer base.

Report Metric Details
Market size value in 2022 USD 1.5 billion
Market size value in 2031 USD 3.05 billion
Growth Rate 8.2%
Base year 2023
Forecast period 2024-2031
Forecast Unit (Value) USD Billion
Segments covered
  • Product
    • Consumables, Instruments
  • Technology
    • Bio-Layer Interferometry, Differential Scanning Calorimetry, Isothermal Titration Calorimetry, Surface Plasmon Resonance, Mass Spectrometry, Other LFD Technologies
  • Application
    • Binding Kinetics, Binding Thermodynamics, Endogenous Receptor Detection, Hit Confirmation, Lead Generation, Others
  • End user
    • Pharmaceutical & Biotechnology Companies, Academic & Research Institutes, Contract Research Organizations
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Agilent Technologies, Inc. (USA) 
  • Danaher Corporation (USA) 
  • PerkinElmer, Inc. (USA) 
  • GE Healthcare (USA) 
  • Thermo Fisher Scientific Inc. (USA) 
  • Bio-Rad Laboratories, Inc. (USA) 
  • F. Hoffmann-La Roche AG (Switzerland) 
  • Horiba, Ltd. (Japan) 
  • Malvern Panalytical Ltd. (UK) 
  • Bruker Corporation (USA) 
  • Waters Corporation (USA) 
  • Shimadzu Corporation (Japan) 
  • Corning Incorporated (USA) 
  • Hitachi High-Tech Corporation (Japan) 
  • Molecular Devices, LLC (USA) 
  • Sartorius AG (Germany) 
  • BiOptix Analytical LLC (USA) 
  • Attana AB (Sweden) 
  • XanTec Bioanalytics GmbH (Germany)
Customization scope

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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Label Free Detection Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Label Free Detection Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Label Free Detection Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Label Free Detection Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Label Free Detection Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Label Free Detection Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Global Label Free Detection Market size was valued at USD 1.5 billion in 2022 and is poised to grow from USD 1.62 billion in 2023 to USD 3.05 billion by 2031, growing at a CAGR of 8.2% during the forecast period (2024-2031).

Global label free detection market is fragmented in nature as new players are entering the market. These players are adopting numerous strategies such as product launches, joint ventures, mergers and acquisitions, and research and development to gain an edge over their competitors and stay ahead in the competition. 'Agilent Technologies, Inc. (USA) ', 'Danaher Corporation (USA) ', 'PerkinElmer, Inc. (USA) ', 'GE Healthcare (USA) ', 'Thermo Fisher Scientific Inc. (USA) ', 'Bio-Rad Laboratories, Inc. (USA) ', 'F. Hoffmann-La Roche AG (Switzerland) ', 'Horiba, Ltd. (Japan) ', 'Malvern Panalytical Ltd. (UK) ', 'Bruker Corporation (USA) ', 'Waters Corporation (USA) ', 'Shimadzu Corporation (Japan) ', 'Corning Incorporated (USA) ', 'Hitachi High-Tech Corporation (Japan) ', 'Molecular Devices, LLC (USA) ', 'Sartorius AG (Germany) ', 'BiOptix Analytical LLC (USA) ', 'Attana AB (Sweden) ', 'XanTec Bioanalytics GmbH (Germany)'

Companies in the market should have access to a variety of development opportunities as a result of the growth of life sciences research in emerging markets and the development of more sensitive non-marker technologies. Some market drivers for label-free detection include the introduction of cutting-edge technology products and the rise in the use of efficient product delivery. The market for label-free detection presents numerous opportunities for investigating molecule-interaction interactions without labels' quenching effects. Label-free technologies, which are relatively new to the well-established field of high throughput screening, offer opportunities for probing biomolecular interactions without the spatial interference, autofluorescence, or quenching effects of labels.

Collaborations will Provide Market to Flourish during Forecast Period: The Label-Free Detection market is expanding due to technological advancements and collaborations. Bio-layer interferometry (BLI) and surface plasmon resonance (SPR) are two commonly used methods for label-free detection. The first commercially available optically based, single-mode benchtop model for cell-based and biochemical assays is the novel Corning® Epic® BT. Corning's benchtop label-free detection system has a packed design, a lower price point, clear data collection software, and a comprehensive microplate investigation using charge-coupled device (CCD) wavelength shift discovery. The novel system improves assay capabilities and makes it simple for researchers, including academic labs, to access the Epic technology. Advinus Therapeutics was chosen by Corning as a partner for preparing the Corning Epic® label-free detection technology for sale in India. Advinus was able to use Epic for its own drug discovery programs and for providing assay development and screening services to clients in India and around the world thanks to their partnership. The Label-Free Detection Market is expanding thanks to collaborations and technological advancements of this kind.

North America held the largest global label free detection market share in 2021. The extensive funding provided by the region's government and the proliferation of technological advancements have contributed to the region's expansion.

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