Microbiome Sequencing Services Market Size, Share, Growth Analysis, By Service (Sample Preparation, Sequencing and Library Preparation), By Technology (Sequencing by Synthesis (SBS), Sequencing by Ligation (SBL)), By Region - Industry Forecast 2025-2032


Report ID: SQMIG35J2091 | Region: Global | Published Date: March, 2024
Pages: 219 |Tables: 90 |Figures: 76

Microbiome Sequencing Services Market Insights

Microbiome Sequencing Services Market size was valued at USD 1.54 Billion in 2023 and is poised to grow from USD 1.7 Billion in 2024 to USD 3.85 Billion by 2032, growing at a CAGR of 10.7% during the forecast period (2025-2032).

The rapid growth of the market can be associated with factors such as the innovation in genetic technology, the increasing awareness of the human microbiome in health, and the increase in the desire for personalized medicine. Research on the link between the human microbiome and health has also made people want to know more about the microbial communities present within the body and other regions, hence the growing need for microbiome sequencing services. Medicine is using microbiome analysis services. Since microbiome-based medications have been developed to treat various diseases, sequencing services have become more and more popular as a tool to aid in treatment strategies. Multi-omics approaches, which integrate information from transcriptomics, metabolomics, and genomes with microbiome sequencing, are becoming more and more popular. 

Such joint studies yield even better research outputs as they help one appreciate the bond between bacteria and human beings fully. Microbiome-based testing is an expanding field. Employing understanding and advanced techniques of microbiome sequencing services to trace microbes associated with diseases may shore up the likelihood of accurate and early diagnoses by clinicians. Most bioinformatics-related developments tend to follow in the wake of increases in the volume of microbial genomic data. To ascertain the species and functional pathways present in a microbiome, there is a need for more advanced information analysis systems that can deal with complex data sets on the microbiome. Microbiome sequencing applications are available in environmental studies as well as in agriculture. 

US Microbiome Sequencing Services Market is poised to grow at a sustainable CAGR for the next forecast year.

Market snapshot - 2024-2031

Global Market Size

USD 1.37 billion

Largest Segment

Whole-genome

Fastest Growth

Amplicon

Growth Rate

10.9% CAGR

Global Microbiome Sequencing Services Market ($ Bn)
Country Share for North America Region (%)

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Microbiome Sequencing Services Market Segmental Analysis

Global Microbiome Sequencing Services Market is segmented by service, technology, application, end user and region. Based on service, the market is segmented into Sample Preparation, Sequencing and Library Preparation, and Data Analysis. Based on technology, the market is segmented into sequencing by synthesis (SBS), sequencing by ligation (SBL), pyrosequencing, sanger sequencing and others. Based on application, the market is segmented into shotgun sequencing, targeted gene sequencing, RNA sequencing, whole genome sequencing and others. Based on end user, the market is segmented into pharmaceutical and biotechnology companies, academic and research institutes, hospitals and clinics and others. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.

Analysis by Technology 

As per categorization by technology, the market is classified as sequencing by synthesis, sequencing by ligation, pyrosequencing, sanger sequencing, and other technologies. Among these, sequencing by synthesis earned the largest share and continues to hold the dominant global microbiome sequencing services market share. Sequencing by synthesis (SBS) offers improved accuracy and allows for scaling microbial analysis across multiple samples of DNA. This technology is mainly also widely used as it enables the production of complex, dense sequencing data that is vital in studying intricate microbial populations. The ability to obtain such sequencing data has made it possible to explore the human microbiome more, hence informing provision of health care services, personalized medicine and environmental health applications. The accuracy, pricing and the increasing potential of this technology makes it the best technology for microbiome sequencing projects almost globally. 

Due to its proprieties that enhance the correct base calling and sequencing performance, sequencing by ligation (SBL) technology is projected to witness the maximum growth for worldwide microbiome sequencing services over the other technologies available. SBL device is able to produce high throughput as well as produce better resolution especially in decoding difficult genomic regions. As more details for analyzing and understanding the composition and function of the microbiomes become necessary for the healthcare and environmental analysis, SBL is also becoming an important tool for the analysis of complex structures of the microbiomes due to its provision of accurate long reads. Thus, its fast growth is being witnessed making SBL technology to be among the technologies that are enhancing the current state of microbiome sequencing in industries. 

Analysis by Application 

Shotgun sequencing is a cutting-edge innovation driving the global microbiome sequencing services market, offering unmatched depth and breadth in microbial community analysis. Random DNA sequencing, also known as shotgun sequencing, provides an all-encompassing portrait of a microbiome by making it possible to identify both applicable as well as non-applicable strains. It aids in visualizing complex microbiomes and infrequent taxa and hence is commonplace in borderline cases of invaded microbiome research especially, in matters of public health or environmental concerns. Globally, the shotgun sequencing market has been expanding and is likely to success due to its high resolution, versatility in handling different sample types as well as its emergence in personalized medicine ensuring its sustained expansion and penetrance. 

Among all the technologies related to microbiome sequencing services, RNA sequencing (RNA-Seq) is forecasted to grow the most rapid growth owing to its potential to reveal the functional dynamics of microbial populations. It is different from DNA sequencing, which only indicates the presence of microorganisms, as RNA-Seq investigates gene expression, thereby elucidating how microorganisms' function in a given environment. This is particularly valuable in human health, where RNA-Seq can uncover how microbes influence disease states. As researchers focus more on microbial functions and dynamics, RNA sequencing’s ability to uncover this critical data drives its rapid adoption and global microbiome sequencing services market growth. 

Global Microbiome Sequencing Services Market By Type

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Microbiome Sequencing Services Market Regional Insights

North America dominates the global microbiome sequencing services market due to its strong research infrastructure, advanced technological capabilities, and substantial investments in biotechnology and healthcare sectors. The region consists of prominent colleges, research institutes, and biotechnology companies that advocate for, and carry out, microbiome research, respectively especially in the region of genomics and personalized medicine. Additionally, there is a sound regulatory framework already in place in North America enabling the operations of marketing advanced sequencing technologies. In addition, high levels of healthcare awareness, increase in the need for personalized medicine and growth in government funding for research regarding microbiome are also contributing to the dominance of North America in microbiome sequencing services market. 

Europe is the fastest-growing region in the global microbiome sequencing services market due to increasing investment in biotechnology research, advancements in sequencing technologies, and a strong emphasis on personalized healthcare. The region has seen significant growth in microbiome research, particularly in the regions of disease prevention and treatment, due to collaborative efforts among academic institutions, research organizations, and private companies. Furthermore, policies set in place by the government that enhance scientific studies and healthcare inventions are contributing to the growth of the market. Europe’s strategies of embedding microbiome data in clinical practice are already yielding results and coupled with rising healthcare awareness are bound to propel the region to a boom in microbiome sequencing services. 

Global Microbiome Sequencing Services Market By Region
  • Largest
  • Fastest

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Microbiome Sequencing Services Market Dynamics

Microbiome Sequencing Services Market Drivers

Growing Demand for Personalized Medicine 

  • The global microbiome sequencing services market is being propelled by the progressive trend of personalized medicine. Since healthcare approaches are geared towards every individual, microbiome analysis is vital as it provides patient focused composition of microorganisms aiding in the diagnosis and management of the conditions. This leads to the increasing market for such solutions. 

Advancements in Sequencing Technologies 

  • The global microbiome sequencing services market is largely driven by the perpetual upgradation of sequencing technologies. Innovations like high throughput sequencing with many more capabilities and accuracy along with scaling down the costs has enabled more efficient and easily availability of microbiome analysis. These advancements in technology are speeding up research and diagnostic applications which in turn improve the outlook of the market. 

Microbiome Sequencing Services Market Restraints 

High Cost of Sequencing 

  • The high cost of microbiome sequencing services remains a significant restraint in the market. Even though technology has evolved significantly, the cost of sequencing equipment, reagents, and analysis can be often a limiting factor for small research institutions and clinics. This prevents easy uptake and use of the devices, restricting the growth potential of the business. 

Data Complexity and Interpretation 

  • Furthermore, the intricacy of each microbiome and the data it generates poses another challenge. Sequencing alone produces massive quantities of data that can only be effectively analyzed employing potent bioinformatics tools and specialists. Due to the absence of standardization, the heterogeneity associated with methods and their interpretations can inhibit the rapid uptake of the provision of microbiome sequencing services for clinical use. 

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Microbiome Sequencing Services Market Competitive Landscape

Several key players who provide robust sequencing technologies and services characterize the competitive environment of the global microbiome sequencing services market. Leading international companies like Illumina, Thermo Fisher Scientific, and BGI Genomics are at the forefront of high-throughput sequencing solutions. Other companies like Qiagen, Oxford Nanopore Technologies, and Zymo Research are also making their contribution towards the growth of the market with innovative products and increased service provision resulting in healthy competition and technological progression within the microbiome study sector. 

Top Player’s Company Profiles

  • Charles River Laboratories 
  • Eurofins Scientific 
  • BGI 
  • Microbiome Insights Inc. 
  • MR DNA 
  • Baseclear BV 
  • Clinical Microbiomics AS 
  • Zymo Research 
  • Rancho Biosciences 
  • Metabiomics 
  • CosmosID 
  • ZIFO 
  • Shanghai Realbio Technology (RBT) Co., Ltd. 
  • Second Genome

Recent Developments

  • In October 2024, Illumina made a statement regarding the capacity of its recently launched high-throughput sequencing platform, the NovaSeq X. Its primary purpose is to push further the possibilities of microbiome research regarding accuracy as well as efficiency speeds. This is further anticipated to propel the progress of microbiome sequencing and provide an effective means for researchers to delve deeper into the microbial flora. 
  • In September 2024, Thermo Fisher Scientific unveiled a next-generation microbiome analysis platform that integrates advanced DNA sequencing technologies with AI-driven analytics. This platform will facilitate the microarray data interpretation by allowing the researchers and clinicians to understand the microbial communities in-depth and derive more useful information about them which will enhance the accuracy of diagnosis and treatment approaches in personalized medicine. 
  • In August 2024, BGI Genomics introduced its MGISEQ-T7 sequencing system, which aimed to facilitate research, especially within microbial genomics. With increased speed and accuracy in DNA sequencing, this innovation will advance the study of the microbiome in clinical and environmental settings on a wider scale. The affordability level of the system is likely to make microbiome sequencing more available worldwide. 

Microbiome Sequencing Services Key Market Trends

  • Rising Integration of Artificial Intelligence in Microbiome Analysis: The global microbiome sequencing services market trends are seeing a drastic increase in the application of Artificial Intelligence and machine learning integrated technologies. Such tools assist with the enhanced analysis and understanding of more complex microbiome data towards better microbial functioning as well as health and disease preventive measures. 
  • Increasing Application of Microbiome Research in Personalized Medicine: Personalized medicine is a major driver for the growth of the global microbiome sequencing services market. In disciplines such as cancer treatment, gastrointestinal disorders, and immunotherapy, researchers and healthcare practitioners are using microbiome data to provide personalized care by devising treatment plans anchored on specific microbial profiles.

Microbiome Sequencing Services Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research. 

As per SkyQuest analysis, in conclusion, the global microbiome sequencing services industry is on the rise primarily due to technology developments, the rise in demand for personalized medicine, and the increasing awareness about the importance of human microbiome. Developments such as high-quality sequencing and incorporation of artificial intelligence are advancing research and therefore both clinical and environmental practices. 

Nonetheless, limitations such as costly requirements and intricate data analysis still exist. In the recent future, the evolution of the market; combination of different strategies, and proliferation of sequencing techniques will be key drivers of progress in precision medicine, diagnostics, and customization of health care products. 

Report Metric Details
Market size value in 2022 USD 1.37 billion
Market size value in 2031 USD 3.48 billion
Growth Rate 10.9%
Base year 2023
Forecast period 2024-2031
Forecast Unit (Value) USD Billion
Segments covered
  • Service
    • Sample Preparation, Sequencing and Library Preparation, Data Analysis
  • Technology
    • Sequencing by Synthesis (SBS), Sequencing by Ligation (SBL), Pyrosequencing, Sanger Sequencing, Others
  • Application
    • Shotgun Sequencing, Targeted Gene Sequencing, RNA Sequencing, Whole Genome Sequencing, Others
  • End User
    • Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, Hospitals and Clinics, Others
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Charles River Laboratories 
  • Eurofins Scientific 
  • BGI 
  • Microbiome Insights Inc. 
  • MR DNA 
  • Baseclear BV 
  • Clinical Microbiomics AS 
  • Zymo Research 
  • Rancho Biosciences 
  • Metabiomics 
  • CosmosID 
  • ZIFO 
  • Shanghai Realbio Technology (RBT) Co., Ltd. 
  • Second Genome
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Microbiome Sequencing Services Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Microbiome Sequencing Services Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Microbiome Sequencing Services Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Microbiome Sequencing Services Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Microbiome Sequencing Services Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Microbiome Sequencing Services Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Global Microbiome Sequencing Services Market size was valued at USD 1.37 billion in 2022 and is poised to grow from USD 1.52 billion in 2023 to USD 3.48 billion by 2031, growing at a CAGR of 10.9% during the forecast period (2024-2031).

Several key players who provide robust sequencing technologies and services characterize the competitive environment of the global microbiome sequencing services market. Leading international companies like Illumina, Thermo Fisher Scientific, and BGI Genomics are at the forefront of high-throughput sequencing solutions. Other companies like Qiagen, Oxford Nanopore Technologies, and Zymo Research are also making their contribution towards the growth of the market with innovative products and increased service provision resulting in healthy competition and technological progression within the microbiome study sector.  'Charles River Laboratories ', 'Eurofins Scientific ', 'BGI ', 'Microbiome Insights Inc. ', 'MR DNA ', 'Baseclear BV ', 'Clinical Microbiomics AS ', 'Zymo Research ', 'Rancho Biosciences ', 'Metabiomics ', 'CosmosID ', 'ZIFO ', 'Shanghai Realbio Technology (RBT) Co., Ltd. ', 'Second Genome'

The global microbiome sequencing services market is being propelled by the progressive trend of personalized medicine. Since healthcare approaches are geared towards every individual, microbiome analysis is vital as it provides patient focused composition of microorganisms aiding in the diagnosis and management of the conditions. This leads to the increasing market for such solutions. 

Rising Integration of Artificial Intelligence in Microbiome Analysis: The global microbiome sequencing services market trends are seeing a drastic increase in the application of Artificial Intelligence and machine learning integrated technologies. Such tools assist with the enhanced analysis and understanding of more complex microbiome data towards better microbial functioning as well as health and disease preventive measures. 

North America dominates the global microbiome sequencing services market due to its strong research infrastructure, advanced technological capabilities, and substantial investments in biotechnology and healthcare sectors. The region consists of prominent colleges, research institutes, and biotechnology companies that advocate for, and carry out, microbiome research, respectively especially in the region of genomics and personalized medicine. Additionally, there is a sound regulatory framework already in place in North America enabling the operations of marketing advanced sequencing technologies. In addition, high levels of healthcare awareness, increase in the need for personalized medicine and growth in government funding for research regarding microbiome are also contributing to the dominance of North America in microbiome sequencing services market. 

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