Microbubbles/Ultrasound Contrast Agents Market Size, Share, Growth Analysis, By Disease Area(Cardio-vascular, Abdominal, Others), By Application(Diagnostic imaging, Drug delivery, Others), By End Use(Diagnostic centers, Hospitals, Others), By Region(North America, Europe, Asia-Pacific, Latin America), By Region - Industry Forecast 2025-2032


Report ID: SQMIG35H2055 | Region: Global | Published Date: April, 2024
Pages: 219 |Tables: 119 |Figures: 78

Microbubbles/Ultrasound Contrast Agents Market Insights

Microbubbles/Ultrasound Contrast Agents Market size was valued at USD 1.94 Billion in 2023 and is poised to grow from USD 2.02 Billion in 2024 to USD 2.77 Billion by 2032, growing at a CAGR of 4.00% during the forecast period (2025-2032).

A substance that is typically transparent to X-ray and is utilized in medical imaging to accelerate the contrast of fluids or structures is referred to as contrast media or contrast agent. For contrast ultrasound imaging, microbubbles are utilized as a blood pool agent in radiology and cardiology. Applications like gene therapy, drug delivery, molecular imaging, and stem cell delivery make extensive use of them.

Using ligand molecules that are restricted to disease-specific molecular markers, microbubbles can also function. The microbubble-based ultrasound contrast agents' primary functions include monitoring the biomarker condition of the vascular endothelium, imaging inflammation, observing the vasculature of tumors, and other tasks.

Microbubbles are injected intravenously and function similarly to red blood cells in the blood's circulation. When gas bubbles are subjected to general frequency ultrasound pulses, their diameters can vary, resulting in a powerful echo from the perfused tissue area.

The echogenicity and soft tissue surrounding of gasses differ greatly. As a result, utilizing microbubble contrast agents for ultrasonic diagnosis enhances the ultrasound reflection or backscattering, resulting in a distinctive echocardiogram with increased contrast.

US Microbubbles/Ultrasound Contrast Agents Market is poised to grow at a sustainable CAGR for the next forecast year.

Market snapshot - 2025-2032

Global Market Size

USD 1.87 billion

Largest Segment

cardiovascular diseases

Fastest Growth

cardiovascular diseases

Growth Rate

4.00% CAGR

Global Microbubbles Ultrasound Contrast Agents Market 2021-2030 ($ Bn)
Country Share for Europe Region- 2021 (%)

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Microbubbles/Ultrasound Contrast Agents Market Segmental Analysis

Global Microbubbles/Ultrasound Contrast Agents Market is segmented by Disease Area, Application, End Use, and region. Based on Disease Area, the market can be segmented into Cardio-vascular, Abdominal, Others. Based on Application, the market is segmented into Diagnostic imaging, Drug delivery, Others. Based on End-Use , the market is segmented into Diagnostic centers, Hospitals, Others. Based on region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.

Analysis by Disease Area

Based on the Disease area, Due to an increase in the prevalence of various chronic cardiovascular diseases, an increase in the demand for microbubbles in echocardiography imaging procedures, an increase in the mortality rate associated with heart attacks and strokes, and an increase in the demand for advanced diagnosis technologies, the cardiovascular diseases segment is anticipated to expand at a significant rate over the course of the forecast period.

Analysis by Application

Based on the application, The market for microbubbles and ultrasound contrast agents was dominated by molecular imaging.This was mostly because more and more molecular imaging techniques based on ultrasound were using microbubbles to accurately diagnose various diseases.The use of microbubbles in molecular imaging applications is further encouraged by the rising demand for targeted therapies, the need to monitor the biomarker status of vascular endothelium, the visualization of tumor vasculature, and the imaging of inflammation and ischemia-reperfusion injury zones.

Global Microbubbles Ultrasound Contrast Agents Market By diseases 2021 (%)

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Microbubbles/Ultrasound Contrast Agents Market Regional Insights

Europe is anticipated to be dominant in the microbubbles/ultrasound contrast agents market. The growth of the global microbubbles/ultrasound contrast agents market in North America and Europe is driven by an increase in the geriatric population, an increase in the incidence and prevalence of chronic diseases, a well-established healthcare infrastructure, an increase in the cost of research and development, an increase in the adoption of advanced technologies, and higher healthcare expenditure in the regions. India and China are expected to dominate the microbubbles/ultrasound contrast agents market in Asia-Pacific during the forecast period due to their large patient bases, rising awareness, increased government efforts to improve public health, and developed healthcare infrastructure. Due to the increasing investments made by market participants in these regions, it is anticipated that the global market for microbubbles/ultrasound contrast agents will expand during the forecast period.

Global Microbubbles Ultrasound Contrast Agents Market By Geography, 2021-2030
  • Largest
  • Fastest

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Microbubbles/Ultrasound Contrast Agents Market Dynamics

Drivers

Advancement of Technology to Bolster Market Growth

  • The use of microbubbles and ultrasound contrast agents in molecular imaging is further driven by the growing demand for targeted therapies and the need to monitor the status of the biomarker in the vascular endothelium. During the forecast period, the microbubbles/ultrasound contrast agents market is anticipated to expand due to advancements in ultrasound technologies, an increase in the demand for targeted diagnostic tools, the advantages of microbubbles/ultrasound contrast agents over traditional diagnostic tools, and an increase in the prevalence of chronic diseases.

Restraints

Short Lifespan to Hinder Market Growth

  • The short lifespan of microbubbles, which is a major drawback, is expected to stifle the market's expansion over the forecast period.

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Microbubbles/Ultrasound Contrast Agents Market Competitive Landscape

The major players covered in the microbubble contrast media market , while GE Healthcare is committed to providing a broad comprehensive portfolio of CM products that help meet your patient and procedural needs across a multitude of modalities.

Top Players Company Profiles

  • General Electric Company
  • Bracco Imaging S.p.A.
  • Lantheus Holdings, Inc.
  • Daiichi Sankyo Company, Limited
  • Bayer AG
  • Fujifilm Holdings Corporation
  • Sanofi S.A.
  • Siemens Healthineers AG
  • Guerbet Group
  • nanoPET Pharma GmbH
  • MBI Co., Ltd.
  • Trivitron Healthcare
  • Unilife Corporation
  • PTW Freiburg GmbH
  • Esaote SpA
  • Mindray Medical International Limited
  • Samsung Electronics Co., Ltd.
  • Shimadzu Corporation
  • Philips Healthcare
  • Canon Medical Systems Corporation

Recent Developments

  • In 2022, The University of Texas MD Anderson Cancer Center Researchers developed an ultrasound-guided cancer immunotherapy platform that generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade. The findings from the preclinical study were published in Nature Nanotechnology.

Microbubbles/Ultrasound Contrast Agents Key Market Trends

  • In cardiology and radiology, microbubbles are utilized as blood-pool agents for contrast ultrasound imaging. They are now being recognized for their potential as targeted agents for molecular imaging. Using ligand molecules that bind to disease-related molecular markers, microbubbles can be made functional. Monitoring the biomarker status of vascular endothelium, visualizing tumor vasculature, and imaging inflammation and ischemia-reperfusion injury zones and thrombi are all potential clinical applications of molecular imaging with microbubble-based ultrasound contrast agents.

Microbubbles/Ultrasound Contrast Agents Market SkyQuest Analysis

Sky Quest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected using Primary Exploratory Research backed by robust Secondary Desk research.

According to our Global Microbubbles/Ultrasound Contrast Agents Market analysis, A large portion of North America's market share is primarily explained by the region's ageing population, rising chronic disease rates, well-developed healthcare system with a widespread network of suppliers and distributors, higher adoption of cutting-edge technologies, rising technological advancements in healthcare, and higher healthcare spending overall, particularly in the U.S.

But during the forecast period, the Asia-Pacific region is expected to grow the fastest. This is largely because of rising healthcare spending, better healthcare infrastructure, rising living standards with rising income of middle class population, growing healthcare awareness, and an aging population that will lead to an increase in chronic disease prevalence in Asian countries.

Report Metric Details
Market size value in 2023 USD 1.94 Billion
Market size value in 2032 USD 2.77 Billion
Growth Rate 4.00%
Base year 2024
Forecast period 2025-2032
Forecast Unit (Value) USD Billion
Segments covered
  • Disease Area
    • Cardio-vascular, Abdominal, Others
  • Application
    • Diagnostic imaging, Drug delivery, Others
  • End Use
    • Diagnostic centers, Hospitals, Others
  • Region
    • North America, Europe, Asia-Pacific, Latin America, and Middle East & Africa
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • General Electric Company
  • Bracco Imaging S.p.A.
  • Lantheus Holdings, Inc.
  • Daiichi Sankyo Company, Limited
  • Bayer AG
  • Fujifilm Holdings Corporation
  • Sanofi S.A.
  • Siemens Healthineers AG
  • Guerbet Group
  • nanoPET Pharma GmbH
  • MBI Co., Ltd.
  • Trivitron Healthcare
  • Unilife Corporation
  • PTW Freiburg GmbH
  • Esaote SpA
  • Mindray Medical International Limited
  • Samsung Electronics Co., Ltd.
  • Shimadzu Corporation
  • Philips Healthcare
  • Canon Medical Systems Corporation

Recent Developments

  • In 2022, The University of Texas MD Anderson Cancer Center Researchers developed an ultrasound-guided cancer immunotherapy platform that generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade. The findings from the preclinical study were published in Nature Nanotechnology.
Customization scope

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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Microbubbles/Ultrasound Contrast Agents Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Microbubbles/Ultrasound Contrast Agents Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Microbubbles/Ultrasound Contrast Agents Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Microbubbles/Ultrasound Contrast Agents Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Microbubbles/Ultrasound Contrast Agents Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Microbubbles/Ultrasound Contrast Agents Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Microbubbles/Ultrasound Contrast Agents Market size was valued at USD 1.94 Billion in 2023 and is poised to grow from USD 2.02 Billion in 2024 to USD 2.77 Billion by 2032, growing at a CAGR of 4.00% during the forecast period (2025-2032).

The major players covered in the microbubble contrast media market , while GE Healthcare is committed to providing a broad comprehensive portfolio of CM products that help meet your patient and procedural needs across a multitude of modalities. 'General Electric Company', 'Bracco Imaging S.p.A.', 'Lantheus Holdings, Inc.', 'Daiichi Sankyo Company, Limited', 'Bayer AG', 'Fujifilm Holdings Corporation', 'Sanofi S.A.', 'Siemens Healthineers AG', 'Guerbet Group', 'nanoPET Pharma GmbH', 'MBI Co., Ltd.', 'Trivitron Healthcare', 'Unilife Corporation', 'PTW Freiburg GmbH', 'Esaote SpA', 'Mindray Medical International Limited', 'Samsung Electronics Co., Ltd.', 'Shimadzu Corporation', 'Philips Healthcare', 'Canon Medical Systems Corporation', 'In 2022, The University of Texas MD Anderson Cancer Center Researchers developed an ultrasound-guided cancer immunotherapy platform that generates systemic antitumor immunity and improves the therapeutic efficacy of immune checkpoint blockade. The findings from the preclinical study were published in Nature Nanotechnology.'

The use of microbubbles and ultrasound contrast agents in molecular imaging is further driven by the growing demand for targeted therapies and the need to monitor the status of the biomarker in the vascular endothelium. During the forecast period, the microbubbles/ultrasound contrast agents market is anticipated to expand due to advancements in ultrasound technologies, an increase in the demand for targeted diagnostic tools, the advantages of microbubbles/ultrasound contrast agents over traditional diagnostic tools, and an increase in the prevalence of chronic diseases.

In cardiology and radiology, microbubbles are utilized as blood-pool agents for contrast ultrasound imaging. They are now being recognized for their potential as targeted agents for molecular imaging. Using ligand molecules that bind to disease-related molecular markers, microbubbles can be made functional. Monitoring the biomarker status of vascular endothelium, visualizing tumor vasculature, and imaging inflammation and ischemia-reperfusion injury zones and thrombi are all potential clinical applications of molecular imaging with microbubble-based ultrasound contrast agents.

Europe is anticipated to be dominant in the microbubbles/ultrasound contrast agents market. The growth of the global microbubbles/ultrasound contrast agents market in North America and Europe is driven by an increase in the geriatric population, an increase in the incidence and prevalence of chronic diseases, a well-established healthcare infrastructure, an increase in the cost of research and development, an increase in the adoption of advanced technologies, and higher healthcare expenditure in the regions. India and China are expected to dominate the microbubbles/ultrasound contrast agents market in Asia-Pacific during the forecast period due to their large patient bases, rising awareness, increased government efforts to improve public health, and developed healthcare infrastructure. Due to the increasing investments made by market participants in these regions, it is anticipated that the global market for microbubbles/ultrasound contrast agents will expand during the forecast period.

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Microbubbles/Ultrasound Contrast Agents Market

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