Narcolepsy Drugs Market Size, Share, Growth Analysis, By Disease Type(Daytime Extreme Sleepiness, Cataplexia, and Other Disease Type), By Therapeutics Type(Central Nervous System Stimulants, Tricyclic Antidepressants, Sodium Oxybate, Selective Serotonin Reuptake Inhibitor), By Region - Industry Forecast 2025-2032


Report ID: SQMIG35I2087 | Region: Global | Published Date: October, 2024
Pages: 219 |Tables: 90 |Figures: 75

Narcolepsy Drugs Market Insights

Narcolepsy Drugs Market size was valued at USD 3.7 Billion in 2023 and is poised to grow from USD 4.05 Billion in 2024 to USD 7.67 Billion by 2032, growing at a CAGR of 9.5% during the forecast period (2025-2032).

Increasing awareness regarding mental health and rising prevalence of multiple sleep disorders are projected to alter the global narcolepsy drugs market growth in the future. Rising number of people being diagnosed with narcolepsy, high investments in the development of novel narcolepsy drugs, and increasing demand for lifestyle improvement are key factors promoting the sales of narcolepsy drugs going forward. Expedition of the approval process for narcolepsy drugs by regulatory bodies and governments to satisfy the unmet medical needs of patients are also estimated to create new opportunities for narcolepsy drug companies in the long run. Moreover, advancements in drug discovery and development technologies are also expected to benefit the adoption of narcolepsy drugs on a global level. On the contrary, lack of awareness, side effects associated with the use of narcolepsy drugs, and competition from non-pharmacological therapies and treatments are slated to slow down narcolepsy drug demand across the study period and beyond.

US Narcolepsy Drugs Market  is poised to grow at a sustainable CAGR for the next forecast year.

Market snapshot - 2024–2031

Global Market Size

USD 3.4 billion

Largest Segment

Hospitals

Fastest Growth

Tricyclic Antidepressants

Growth Rate

9.60% CAGR

Global Narcolepsy Drugs Market ($ Bn)
Country Share for North America Region (%)

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Narcolepsy Drugs Market Segmental Analysis

Global Narcolepsy Drugs Market is segmented by Disease Type, Therapeutics Type, and region. Based on Disease Type, the market is segmented into Daytime Extreme Sleepiness, Cataplexia, and Other Disease Type. Based on Therapeutics Type, the market is segmented into Central Nervous System Stimulants, Tricyclic Antidepressants, Sodium Oxybate, Selective Serotonin Reuptake Inhibitor, and Other Therapeutic Type. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & and Africa.

Analysis by Therapeutics Type 

Sodium oxybate is forecasted to account for a substantial narcolepsy drugs market share in the future. High prescription of sodium oxybate therapeutics for most narcoleptic conditions by medical professionals and availability of favorable reimbursement for the same are expected to aid the dominance of this segment going forward. Extensive use of sodium oxybate therapeutics for the treatment of cataplexy in children and adults above the age of 7 also contributes to the high market share of this segment. However, sodium oxybate is also linked with serious side effects such as breathing issues, agitation, aggression, excessive drowsiness, nausea, etc., which could impede the share of this segment.  

Meanwhile, central nervous system stimulants are expected to account for the second-largest share of the global narcolepsy drugs industry going forward. Growing investments in the research and development of novel central nervous stimulants that can treat narcolepsy are expected to help create new opportunities for narcolepsy drug companies targeting this segment. These therapeutics work by stimulating wakefulness in the central nervous system. Modafinil (Provigil), Armodafinil (Nuvigil), and Solriamfetol are some of the most popularly used central nervous system stimulants for narcolepsy. The prime benefit of these therapeutics is that they have a less risk of causing habitual dependence as compared to other types of therapeutics.  

Analysis by Disease Type 

Daytime extreme sleepiness is projected to account for a major chunk of the global narcolepsy drugs market share in the future. The high adoption of sedentary lifestyles, increased stress and anxiety, and growing number of sleep disorders are expected to be key factors contributing to the dominance of this segment. Rising cases of narcolepsy around the world and increased public awareness regarding the same are also expected to bolster the high market share of daytime extreme sleepiness diseases. Providing narcolepsy drugs for the treatment of extreme sleepiness is becoming more and more important as people become aware of this condition around the world.  

Meanwhile, the cataplexia segment is expected to emerge as a highly opportune one for narcolepsy drug companies in the long run. Rising number of narcoleptic patients experiencing cataplexy i.e. sudden muscle weakness is expected to help create new business scope for narcolepsy drug suppliers targeting cataplexia in the future. Lack of orexins and sudden emotions are key factors resulting in high incidence of cataplexia among people around the world. Launch of new initiatives to promote awareness regarding cataplexy and investments in the development of therapeutics for the treatment of the same are also driving demand outlook. 

Global Narcolepsy Drugs Market By End-user

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Narcolepsy Drugs Market Regional Insights

North America is estimated to emerge as the leader in terms of narcolepsy drug demand owing to high awareness regarding mental health and growing prevalence of narcolepsy. Growing investments in the research and development of novel narcolepsy drugs and surging incidence of sleep disorders are also aiding the dominance of North America. The United States and Canada are estimated to be the top markets for narcolepsy drug providers operating in this region. High availability of favorable reimbursement policies for narcolepsy treatment in North America is also anticipated to bolster the sales of narcolepsy drugs going forward.  

The Asia Pacific region is emerging as a highly opportune market for narcolepsy drug companies in the world. Launch of new initiatives to promote awareness regarding narcolepsy, high investments in healthcare infrastructure development, and high emphasis on improving quality of life are expected to promote sales of narcolepsy drugs in this region. China and India are expected to be the leading markets for narcolepsy drugs in the Asia Pacific region across the study period and beyond. High investments in sleep medicine R&D are also expected to create new opportunities for narcolepsy drug companies.

Global Narcolepsy Drugs Market By Region
  • Largest
  • Fastest

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Narcolepsy Drugs Market Dynamics

Narcolepsy Drugs Market Drivers

Growing Mental Health Awareness 

  • Mental health awareness has increased rapidly in recent years as the incidence of stress, anxiety, and other mental health disorders such as narcolepsy has also risen. Launch of new efforts and initiatives to solve these mental health issues and help patients affected from the same are expected to bolster the global narcolepsy drugs market outlook in the future.   

Emphasis on Lifestyle Improvement 

  • People affected by narcolepsy have significantly reduced quality of life as they experience extreme daytime sleepiness and sudden muscle weaknesses. Efforts to promote healthy lifestyles and reduce the sedentary nature of people’s life are expected to promote the sales of narcolepsy drugs over the coming years.  

Narcolepsy Drugs Market Restraints 

Limited Awareness in Developing Regions 

  • Awareness regarding symptoms and effects of narcolepsy is quite limited in most parts of the world, especially in developing and underdeveloped regions.  This lack of awareness causes most narcoleptic patients going undetected and void of treatment thereby hurting the demand for narcolepsy drugs as well. Awareness programs and campaigns can easily help in overcoming this restraint.  

Side Effects of Narcolepsy Treatment 

  • Extensive use of narcolepsy drugs has been linked to cardiovascular issues, nervous system disturbances, and also the risk of dependence leading to substance abuse as well. Increasing awareness regarding these ill effects associated with the use of narcolepsy drugs is projected to slow down the overall narcolepsy drugs market forecast in the long run.

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Narcolepsy Drugs Market Competitive Landscape

Narcolepsy drug providers are projected to focus on reducing their time-to-market by fast-tracking their approval process. Investing in R&D of novel narcolepsy drugs is also expected to be a key strategy for all narcolepsy drug companies in the future. Raising awareness regarding narcolepsy is expected to be crucial for narcolepsy drug providers looking to expand their business scope on a global level. 

Narcolepsy Drugs Market Top Player's Company Profiles

  • Jazz Pharmaceuticals plc 
  • Teva Pharmaceutical Industries Ltd. 
  • Bioprojet Pharma SARL 
  • Novartis International AG 
  • Takeda Pharmaceutical Company 
  • Avadel Pharmaceuticals 
  • Mylan N.V. (now part of Viatris) 
  • Aurobindo Pharma 
  • Glenmark Pharmaceuticals 
  • Lupin Pharmaceuticals 
  • Otsuka Pharmaceutical 
  • Biogen 
  • Theravance Biopharma 
  • Ligand Pharmaceuticals 
  • Flamel Technologies (now Avadel Pharmaceuticals) 
  • Biocodex 
  • Sun Pharmaceutical Industries 
  • Cipla Limited 
  • Dr. Reddy’s Laboratories 
  • Pfizer Inc. 

Narcolepsy Drugs Market Recent Developments

  • In June 2024, Harmony Biosciences, a company focused on developed treatments for rare diseases announced that it got an approval for supplemental New Drug Application (sNDA) for WAKIX® (pitolisant) tablets by the FDA. The treatment is designed for pediatric patients of age 6 or older.  
  • In June 2024, Taked Pharmaceuticals, a renowned pharmaceutical company from Japan revealed its Phase 2 clinical trial findings for a novel narcolepsy treatment. TAK-861 drug candidate was planned for a Phase 3 clinical trial in the end of 2024.  
  • In May 2023, Avadel Pharmaceuticals, a leading pharmaceutical company headquartered in Ireland announced that it had won the approval for its new treatment for narcolepsy and cataplexy. The United States Food and Drug Administration (FDA) approved Lumryz as a once-at-bedtime treatment for patients of age 7 or older.

Narcolepsy Drugs Key Market Trends

  • Orexin-based Therapies: Narcolepsy drug providers are projected to focus on the development of orexin-based therapies and treatments going forward. Orexin receptor agonists have shown promise in treating narcolepsy by targeting the underlying causes with fewer side effects as compared to traditional narcolepsy drugs available in the market. Investing in the R&D of orexin-based therapies is slated to be a top narcolepsy drugs market trend for the future.  
  • Personalized Medicine: narcolepsy drug companies can focus on developing personalized drugs and treatments for patients as preference for personalized medicine rises around the world. Tailored therapies based on individual genetic profiles and sleep patterns are gaining traction, improving treatment outcomes thereby also enhancing the overall quality of life for narcoleptic patients. 

Narcolepsy Drugs Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.  

As per SkyQuest analysis, growing incidence of narcolepsy and rising emphasis on mental health around the world are projected to boost sales of narcolepsy drugs in the future. However, limited awareness in developing regions and side effects associated with high use of narcolepsy drugs are expected to slow down the demand for narcolepsy drugs over the coming years. Availability of favorable reimbursement policies and high incidence of narcolepsy are helping North America spearhead the global narcolepsy drugs market forecast. Use of personalized medicine and development of orexin-based treatment are slated to be key opportunities for narcolepsy drug providers.

Report Metric Details
Market size value in 2022 USD 3.4 billion
Market size value in 2031 USD 7 billion
Growth Rate 9.5%
Base year 2023
Forecast period 2024–2031
Forecast Unit (Value) USD Billion
Segments covered
  • Disease Type
    • Daytime Extreme Sleepiness, Cataplexia, and Other Disease Type
  • Therapeutics Type
    • Central Nervous System Stimulants, Tricyclic Antidepressants, Sodium Oxybate, Selective Serotonin Reuptake Inhibitor, and Other Therapeutic Type
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Jazz Pharmaceuticals plc 
  • Teva Pharmaceutical Industries Ltd. 
  • Bioprojet Pharma SARL 
  • Novartis International AG 
  • Takeda Pharmaceutical Company 
  • Avadel Pharmaceuticals 
  • Mylan N.V. (now part of Viatris) 
  • Aurobindo Pharma 
  • Glenmark Pharmaceuticals 
  • Lupin Pharmaceuticals 
  • Otsuka Pharmaceutical 
  • Biogen 
  • Theravance Biopharma 
  • Ligand Pharmaceuticals 
  • Flamel Technologies (now Avadel Pharmaceuticals) 
  • Biocodex 
  • Sun Pharmaceutical Industries 
  • Cipla Limited 
  • Dr. Reddy’s Laboratories 
  • Pfizer Inc. 
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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Narcolepsy Drugs Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Narcolepsy Drugs Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Narcolepsy Drugs Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Narcolepsy Drugs Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Narcolepsy Drugs Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Narcolepsy Drugs Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

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FAQs

Global Narcolepsy Drugs Market size was valued at around USD 3.4 billion in 2022 and is expected to rise from USD 3.7 billion in 2023 to reach a value of USD 7 billion by 2031, at a CAGR of 9.5% over the forecast period (2024–2031).

Narcolepsy drug providers are projected to focus on reducing their time-to-market by fast-tracking their approval process. Investing in R&D of novel narcolepsy drugs is also expected to be a key strategy for all narcolepsy drug companies in the future. Raising awareness regarding narcolepsy is expected to be crucial for narcolepsy drug providers looking to expand their business scope on a global level.  'Jazz Pharmaceuticals plc ', 'Teva Pharmaceutical Industries Ltd. ', 'Bioprojet Pharma SARL ', 'Novartis International AG ', 'Takeda Pharmaceutical Company ', 'Avadel Pharmaceuticals ', 'Mylan N.V. (now part of Viatris) ', 'Aurobindo Pharma ', 'Glenmark Pharmaceuticals ', 'Lupin Pharmaceuticals ', 'Otsuka Pharmaceutical ', 'Biogen ', 'Theravance Biopharma ', 'Ligand Pharmaceuticals ', 'Flamel Technologies (now Avadel Pharmaceuticals) ', 'Biocodex ', 'Sun Pharmaceutical Industries ', 'Cipla Limited ', 'Dr. Reddy’s Laboratories ', 'Pfizer Inc. '

Mental health awareness has increased rapidly in recent years as the incidence of stress, anxiety, and other mental health disorders such as narcolepsy has also risen. Launch of new efforts and initiatives to solve these mental health issues and help patients affected from the same are expected to bolster the global narcolepsy drugs market outlook in the future.   

Orexin-based Therapies: Narcolepsy drug providers are projected to focus on the development of orexin-based therapies and treatments going forward. Orexin receptor agonists have shown promise in treating narcolepsy by targeting the underlying causes with fewer side effects as compared to traditional narcolepsy drugs available in the market. Investing in the R&D of orexin-based therapies is slated to be a top narcolepsy drugs market trend for the future.  

North America is estimated to emerge as the leader in terms of narcolepsy drug demand owing to high awareness regarding mental health and growing prevalence of narcolepsy. Growing investments in the research and development of novel narcolepsy drugs and surging incidence of sleep disorders are also aiding the dominance of North America. The United States and Canada are estimated to be the top markets for narcolepsy drug providers operating in this region. High availability of favorable reimbursement policies for narcolepsy treatment in North America is also anticipated to bolster the sales of narcolepsy drugs going forward.  

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