NGS Library Preparation Market Size, Share, Growth Analysis, By Product type(Reagents & Consumables, Instruments & Workstations), By Application(Disease Diagnostics, Drug Discovery, Other Applications.), By sequencing type(Targeted Genome Sequencing, Whole Genome Sequencing, Whole Exome Sequencing, Other Sequencing Types), By end user(Hospitals & Diagnostic Laboratories, Pharmaceutical and Biotechnology Companies, Academic Institutes & Research Centres, Others End Users), By Region - Industry Forecast 2025-2032


Report ID: SQMIG35J2081 | Region: Global | Published Date: February, 2024
Pages: 249 |Tables: 118 |Figures: 80

NGS Library Preparation Market Insights

NGS Library Preparation Market size was valued at USD 3.62 Billion in 2023 and is poised to grow from USD 4.16 Billion in 2024 to USD 12.52 Billion by 2032, growing at a CAGR of 14.8% during the forecast period (2025-2032).

Preparation of the library, sequencing, bioinformatics, and sample pre-processing are just a few of the steps that make up the typical NGS workflow. Preparing DNA or RNA samples to be compatible with a sequencer is one of the most important steps in the NGS workflow. It includes things like adapter ligation, library quantitation, and fragmentation of nucleic acids. For NGS analysis, numerous vendors offer a variety of NGS library preparation solutions. Next-generation sequencing (NGS) library preparation is a crucial process in the NGS workflow. Preparing the nucleic acid target so that it can be used with the sequencing system is this process. Prior to sequencing, the DNA and RNA samples must be isolated, fragmented, end-repaired, and covalently linked to adapters by ligation or tagmentation. In addition, various instruments, kits, and reagents for the preparation of NGS libraries are available on the market. A well-prepared NGS library's complexity should accurately reflect the sample's complexity, as well as any biases introduced during library preparation. Because the quality of the final DNA or RNA library can have a significant impact on NGS results, it is essential to reduce PCR or other amplification-induced biases while simultaneously maximizing complexity when preparing a DNA or RNA library for NGS.

NGS Library Preparation Market is poised to grow at a sustainable CAGR for the next forecast year.

Market snapshot - 2025-2032

Global Market Size

USD 3.15 billion

Largest Segment

Reagents & Consumables

Fastest Growth

Reagents & Consumables

Growth Rate

14.8% CAGR

Global NGS Library Preparation Market by Product type ($ Bn)
Country Share for North America Region (%)

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NGS Library Preparation Market Segmental Analysis

The NGS Library preparation market is segmented on the basis of product, application, sequencing type, end user and region. Whereas, By product is sub segmented into the Reagents & Consumables, Instruments & Workstations. By Application is sub segmented into the Disease Diagnostics, Drug Discovery, Other Applications. By Sequencing type is sub segmented into the Targeted Genome Sequencing, Whole Genome Sequencing, Whole Exome Sequencing, Other Sequencing Types. By end user is sub segmented into the Hospitals & Diagnostic Laboratories, Pharmaceutical and Biotechnology Companies, Academic Institutes & Research Centres, Others End Users. The region is segmented on the basis of North America, Europe, Asia Pacific, Latin America, Middle East and Africa.

NGS Library Preparation Market Analysis by Product type

In 2022, the reagents & consumables segment is estimated to account for the largest share of the ngs library preparation market. The recurrent demand for reagents and kits for NGS library preparation, the introduction of new library preparation kits, and the growing use of NGS in clinical diagnostics are some of the factors that account for this segment's substantial market share.

NGS Library Preparation Market Analysis by Application

In 2022, the disease diagnostics segment is estimated to account for the largest share of the ngs library preparation market. The high prevalence of cancer and other rare genetic disorders, the growing demand for early disease diagnosis, and the widespread use of NGS for cancer diagnostics all contribute to this segment's substantial market share.

Global NGS Library Preparation Market by Product type

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NGS Library Preparation Market Regional Insights

North America is estimated to account for the largest share of the ngs library preparation market. The widespread use of NGS-based diagnostic tests, substantial investments in research and development, and growing government support for and investments in the region's genome sequencing infrastructure all contribute to North America's dominant market share.

However, the NGS library preparation market is expected to expand at the fastest rate during the forecast period in Asia-Pacific. The development of the region's healthcare infrastructure, the government's increased focus on sequencing projects, the rising prevalence of various chronic and infectious diseases, the large number of patients with gene-associated disorders, and the expansion of research into personalized medicine are all contributing factors to the market's rapid expansion in Asia-Pacific.

Global NGS Library Preparation Market By Region
  • Largest
  • Fastest

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NGS Library Preparation Market Dynamics

NGS Library Preparation Market Drivers

Increasing Investment to Develop Diagnostics to Bolster Market Growth

  • The decreasing costs of sequencing, the rising incidence of genetic disorders, the growing use of NGS in diagnostics, and the rising amount spent on R&D and healthcare are all driving the market for NGS library preparation. Additionally, this market is anticipated to benefit significantly from the growing number of applications for next-generation sequencing and the growing number of businesses working together to develop library preparation protocols.

NGS Library Preparation Market Restraints

Financial Sponsorship to Hinder Market Growth

  • It is anticipated that budgetary constraints in developing nations will significantly impede the expansion of this market. Additionally, major obstacles to the expansion of this market include concerns regarding diagnostic testing regulatory and standardization as well as the limited expertise and sequencing capabilities of mid- and small-sized laboratories.

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NGS Library Preparation Market Competitive Landscape

Major competitors in the industry use a variety of important expansion strategies, including collaborating with existing manufacturers, making acquisitions, and obtaining regulatory approvals for new sample products.

NGS Library Preparation Market Top Players Company Profiles

  • Illumina, Inc.
  • Thermo Fisher Scientific Inc.
  • Agilent Technologies Inc.
  • Qiagen N.V.
  • F. Hoffmann-La Roche AG
  • PerkinElmer Inc.
  • Bio-Rad Laboratories, Inc.
  • Oxford Nanopore Technologies Ltd.
  • Beckman Coulter Inc.
  • Becton, Dickinson and Company
  • Fluidigm Corporation
  • Pacific Biosciences of California Inc.
  • New England Biolabs Inc.
  • Hamilton Company
  • Tecan Group Ltd.
  • Takara Bio Inc.
  • Swift Biosciences Inc.
  • Genohm SA
  • Kapa Biosystems, Inc.
  • WaferGen Bio-systems, Inc.

NGS Library Preparation Market Recent Developments

  • In March 2022, Beckman Coulter, Inc. launched CellMekSPS, which is a fully automated sample preparation system that is used for clinical flow cytometry. This fully automated system offers an on-demand multitude of sample types processing that can help laboratories expand testing capabilities.
  • In June 2022, Bio-Rad Laboratories, Inc. launched its SEQuoia Express Stranded RNA Library Prep Kit at the AGBT 2022. This kit is highly efficient for optimal RNA Sequencing Library Preparation and can be used for comprehensive transcriptome profiling.
  • In April 2022, OPENTRONS launched four new OT-2 workstations for all types of applications, including NGS, PCR, and protein purification. Its NGS workstation automates multiple steps of the pre-sequencing, including library preparations. This expansion is expected to increase the accessibility of automation products to customers.

NGS Library Preparation Key Market Trends

  • The manual preparation of the NGS library takes a lot of time and effort, and it requires a lot of experience and attention to detail. However, researchers are now able to save valuable man-hours by utilizing automated and robotic library preparation solutions. Additionally, sequencing library preparation can be automated to increase throughput, reduce hands-on time, and minimize errors.

NGS Library Preparation Market SkyQuest Analysis

Sky Quest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected using Primary Exploratory Research backed by robust Secondary Desk research.

According to our global NSG library preparation market analysis, The increasing prevalence of genetic disorders, the falling cost of sequencing, the expanding use of NGS in diagnostics, and the rising R&D expenditures all contribute to the market's expansion. Additionally, there will likely be significant market expansion potential due to the expanding uses of next-generation sequencing and the growing number of corporate partnerships for the development of library preparation techniques.

Report Metric Details
Market size value in 2023 USD 3.62 Billion
Market size value in 2032 USD 12.52 Billion
Growth Rate 14.8%
Base year 2024
Forecast period 2025-2032
Forecast Unit (Value) USD Billion
Segments covered
  • Product type
    • Reagents & Consumables, Instruments & Workstations
  • Application
    • Disease Diagnostics, Drug Discovery, Other Applications.
  • sequencing type
    • Targeted Genome Sequencing, Whole Genome Sequencing, Whole Exome Sequencing, Other Sequencing Types
  • end user
    • Hospitals & Diagnostic Laboratories, Pharmaceutical and Biotechnology Companies, Academic Institutes & Research Centres, Others End Users
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Illumina, Inc.
  • Thermo Fisher Scientific Inc.
  • Agilent Technologies Inc.
  • Qiagen N.V.
  • F. Hoffmann-La Roche AG
  • PerkinElmer Inc.
  • Bio-Rad Laboratories, Inc.
  • Oxford Nanopore Technologies Ltd.
  • Beckman Coulter Inc.
  • Becton, Dickinson and Company
  • Fluidigm Corporation
  • Pacific Biosciences of California Inc.
  • New England Biolabs Inc.
  • Hamilton Company
  • Tecan Group Ltd.
  • Takara Bio Inc.
  • Swift Biosciences Inc.
  • Genohm SA
  • Kapa Biosystems, Inc.
  • WaferGen Bio-systems, Inc.

NGS Library Preparation Market Recent Developments

  • In March 2022, Beckman Coulter, Inc. launched CellMekSPS, which is a fully automated sample preparation system that is used for clinical flow cytometry. This fully automated system offers an on-demand multitude of sample types processing that can help laboratories expand testing capabilities.
  • In June 2022, Bio-Rad Laboratories, Inc. launched its SEQuoia Express Stranded RNA Library Prep Kit at the AGBT 2022. This kit is highly efficient for optimal RNA Sequencing Library Preparation and can be used for comprehensive transcriptome profiling.
  • In April 2022, OPENTRONS launched four new OT-2 workstations for all types of applications, including NGS, PCR, and protein purification. Its NGS workstation automates multiple steps of the pre-sequencing, including library preparations. This expansion is expected to increase the accessibility of automation products to customers.
Customization scope

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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on NGS Library Preparation Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on NGS Library Preparation Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the NGS Library Preparation Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the NGS Library Preparation Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the NGS Library Preparation Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the NGS Library Preparation Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

NGS Library Preparation Market size was valued at USD 3.62 Billion in 2023 and is poised to grow from USD 4.16 Billion in 2024 to USD 12.52 Billion by 2032, growing at a CAGR of 14.8% during the forecast period (2025-2032).

Major competitors in the industry use a variety of important expansion strategies, including collaborating with existing manufacturers, making acquisitions, and obtaining regulatory approvals for new sample products. 'Illumina, Inc.', 'Thermo Fisher Scientific Inc.', 'Agilent Technologies Inc.', 'Qiagen N.V.', 'F. Hoffmann-La Roche AG', 'PerkinElmer Inc.', 'Bio-Rad Laboratories, Inc.', 'Oxford Nanopore Technologies Ltd.', 'Beckman Coulter Inc.', 'Becton, Dickinson and Company', 'Fluidigm Corporation', 'Pacific Biosciences of California Inc.', 'New England Biolabs Inc.', 'Hamilton Company', 'Tecan Group Ltd.', 'Takara Bio Inc.', 'Swift Biosciences Inc.', 'Genohm SA', 'Kapa Biosystems, Inc.', 'WaferGen Bio-systems, Inc.', 'In March 2022, Beckman Coulter, Inc. launched CellMekSPS, which is a fully automated sample preparation system that is used for clinical flow cytometry. This fully automated system offers an on-demand multitude of sample types processing that can help laboratories expand testing capabilities.', 'In June 2022, Bio-Rad Laboratories, Inc. launched its SEQuoia Express Stranded RNA Library Prep Kit at the AGBT 2022. This kit is highly efficient for optimal RNA Sequencing Library Preparation and can be used for comprehensive transcriptome profiling.', 'In April 2022, OPENTRONS launched four new OT-2 workstations for all types of applications, including NGS, PCR, and protein purification. Its NGS workstation automates multiple steps of the pre-sequencing, including library preparations. This expansion is expected to increase the accessibility of automation products to customers.'

The decreasing costs of sequencing, the rising incidence of genetic disorders, the growing use of NGS in diagnostics, and the rising amount spent on R&D and healthcare are all driving the market for NGS library preparation. Additionally, this market is anticipated to benefit significantly from the growing number of applications for next-generation sequencing and the growing number of businesses working together to develop library preparation protocols.

The manual preparation of the NGS library takes a lot of time and effort, and it requires a lot of experience and attention to detail. However, researchers are now able to save valuable man-hours by utilizing automated and robotic library preparation solutions. Additionally, sequencing library preparation can be automated to increase throughput, reduce hands-on time, and minimize errors.

North America is estimated to account for the largest share of the ngs library preparation market. The widespread use of NGS-based diagnostic tests, substantial investments in research and development, and growing government support for and investments in the region's genome sequencing infrastructure all contribute to North America's dominant market share.

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