USD 12.57 Billion
Nucleic Acid Therapeutics Market Size, Share, Growth Analysis, By Technology(Anti-sense and Anti-gene, Short Inhibitory Sequences, Gene Transfer Therapy, Nucleoside Analogs), By Application(Monogenetic Disorders, Thalassemia, Sickle Cell Anemia, Hemophilia), By Surgery(Hospitals and Academic & Research Institutes), By Region - Industry Forecast 2025-2032
Report ID:
SQMIG35A2868 |
Region:
Global |
Published Date: April, 2024
Pages:
210
|Tables:
100
|Figures:
76
Nucleic Acid Therapeutics Market Insights
Nucleic Acid Therapeutics Market size was valued at USD 12.57 Billion in 2023 and is poised to grow from USD 13.09 Billion in 2024 to USD 18.05 Billion by 2032, growing at a CAGR of 4.1% during the forecast period (2025-2032).
Genes are naturally made of chemicals called nucleic acids, which are also the main molecules that carry information to cells Deoxyribonucleic acid (DNA), ribonucleic acid (RNA), and synthetic nucleic acids are three types of nucleic acids. Endogenous nucleic acids are specifically recognized by Watson-Crick base pairing, mediating their universal mode of action. Nucleic acid-based drugs are used to treat many chronic diseases. It exhibits significant therapeutic effects in chronic conditions such as cancer, epilepsy, diabetes, tuberculosis and AIDS. For example, the nucleic acid therapeutics market has received a lot of interest lately as it appears to have a significant impact on the treatment of chronic diseases.
Global nucleic acid therapeutics market is expected to grow rapidly owing to several new therapies now approved and developed. Growth in pharmaceutical and healthcare industry, biopharmaceuticals, DNA therapeutics all contribute to the nucleic acid therapeutics market spike.
Market snapshot - 2025-2032
Global Market Size
Largest Segment
Anti-sense and Anti-gene
Fastest Growth
Gene Transfer Therapy
Growth Rate
4.1% CAGR
Global Nucleic Acid Therapeutics Market ($ Bn)
Country Share for North America Region (%)
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Nucleic Acid Therapeutics Market Segmental Analysis
Based on technology, the nucleic acid-based therapeutics market segmentation includes anti-sense and anti-gene, short inhibitory sequences, gene transfer therapy, nucleoside analogs, ribozymes, and aptamers. Based on application, the nucleic acid-based therapeutics market segmentation includes monogenetic disorders, thalassemia, sickle cell anemia, hemophilia, cystic fibrosis, multi-genetic disorders, cancer, diabetes, neurodegenerative diseases, cardiovascular diseases, oncology, cardiology etc. The nucleic acid-based therapeutics market data has been bifurcated by surgery into hospitals and academic & research institutes. The study provides market insights into North America, Europe, Asia-Pacific, Latin America, The Middle East and Africa.
Analysis by Technology
Technologically, the anti-sense anti-gene segment was expected to dominate the market by 2022, holding the largest market share in terms of global nucleic acid therapeutics market revenue. This is due to lack of diseases conditions such as cancer and increasing genetic disorders, which are major therapeutic targets for antisense and anti-gene therapy.
However, the gene transfer therapy segment is predicted to be the fastest growing segment during the forecast period, with the highest CAGR. This is due to the increased focus on personalized medicine and the potential of gene transfer therapy to treat a variety of genetic diseases, including rare genetic diseases.
Analysis by Application
In terms of consumption, the oncology segment is expected to dominate with the highest CAGR. Cancer detection is one of the most common imaging procedures worldwide. This is due to increasing knowledge of early detection of cancer, high prevalence of cancer, usefulness of diagnosis in the treatment and management of various cancers. Several pharmaceutical pipelines show oncology indication, and other factors help it spread upwards. Also, increasing investments in research and development of novel nuclear medicines for cancer therapy can help the sector grow.
The cardiovascular segment is expected to grow significantly over the forecast period owing to the increasing demand for CVD diagnosis. In March 2021, Bracco Diagnostics Inc. will have 100,000 shares and CardioNavix, LLC formed a partnership aimed at improving patient access to the new cardiac PET imaging system. This new system gives patients access to hospitals, physicians and diagnostic centers, for cardiac PET imaging. This initiative can reduce upfront costs and the risk of staff loss by encouraging clinicians to design & implement diagnostic tests. In terms of consumption, the oncology segment is expected to grow at the highest CAGR. Cancer detection is one of the most common imaging procedures worldwide. This is due to increasing knowledge of early detection of cancer, high prevalence of cancer, usefulness of diagnosis in the treatment and management of various cancers. Several pharmaceutical pipelines show oncology indication and other factors help it spread upwards. Also, increasing investments in research and development of novel nuclear medicines for cancer therapy can help the sector grow.
Global Nucleic Acid Therapeutics Market By Technology (%)
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Nucleic Acid Therapeutics Market Regional Insights
North America is predicted to lead the market owing to factors such as high prevalence of chronic diseases such as cancer and diabetes, growing availability of targeted and customized drugs, and supportive government efforts, according to January 2022 CDC National Diabetes Statistical Report More than 130 shows it people in the United States have diabetes. The United States dominates the North American markets.
Asia-Pacific region in the global nucleic acid therapeutics market is expected to grow at a rapid CAGR from 2024 to 2031. Increasing knowledge of nucleic acid testing and research institutions and deal analysis from western developed countries to countries developing in the field. The region is predicted to witness a higher CAGR than other regions in Asia-Pacific due to factors including corporate relocation. Moreover, the Chinese nucleic acid-based drug market held the largest market share, and the Indian nucleic acid-based drug market was the fastest growing market in the Asia-Pacific region.
Global Nucleic Acid Therapeutics Market By Geography
- Largest
- Fastest
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Nucleic Acid Therapeutics Market Dynamics
Drivers
Rising Advancements in Molecular Technologies
- Advances in molecular technologies and ongoing research on omics have led many companies to invest heavily in it. The nucleic acid-based therapeutics market is highly competitive and market share is gained through multiple business strategies. Acquisitions, partnerships or collaborations are key sources of revenue in the marketplace. For example, in August 2022, Merck & Co. will launch a $1. announced a new therapeutic RNA collaboration with Orna Therapeutics. This collaboration includes the discovery, development and commercialization of novel RNA-based therapies for vaccines, infectious diseases, and oncology programs.
Rise in the Chronic Diseases
- Increasing investment in nucleic acid therapeutics due to high prevalence of chronic diseases, genetic and others is expected to boost market growth for example, in March 2023, Switch Therapeutics acquired $52 million in a Series, a funding round co-led by Insight Partners and UCB Ventures. The company used these funds to select and promote siRNA therapies for therapeutic neurological disorders and advance its RNAi technology market players invest in nucleic acid-based therapeutics R&D to expand products in the nucleic acid-based in therapy. For example, in January 2023, Agilent Technologies Inc. will have 100,000 shares. invested $725 million in nucleic acid products. The investment will double the production capacity for active pharmaceutical ingredients (API).
Restraints
Delivery Challenges
- Successful delivery of nucleic acid therapies to target cells remains a major hurdle. Ensuring that therapeutic agents reach the target tissue or cells while avoiding off-target effects can be challenging.
Immunodeficiency
- Nucleic acid therapy can activate the immune system, which can lead to adverse or decreased side effects. Immunosuppressive strategies are essential for the success of these therapies.
Safety Issues
- The long-term safety of nucleic acid therapies, especially gene therapy, is a concern. The possibility of unintended consequences, such as insertion mutagenesis or delayed immune responses, needs to be carefully investigated and addressed.
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Nucleic Acid Therapeutics Market Competitive Landscape
The competitive environment of the Global Nucleic Acid Therapeutics Market is dynamic and characterized by the presence of a mix of well-established brands, emerging players, and niche producers. Innovation is a key competitive factor.
Top Player’s Company Profiles
- agtc
- Wave Life Science Ltd.
- Imugene
- Aileron Therapeutics Inc.
- Akcea Therapeutics
- BioNTech SE
- Biocon
- Biomedica
- Protagonist Therapeutics Inc.
- Replicate Bioscience Inc.
- Eli Lily and Company
- Copernicus Therapeutics Inc.
- Invio Pharmaceuticals Inc.
- Benitec Biopharma
- Alnylam Pharmaceuticals
- Zydus Cadila
- Excision BioTherapeutics
- Pfizer Inc.
- Rhythm Pharmaceuticals Inc.
- Axcella Health Inc.
Recent Developments
- August 2022 Merck & Co. and Orna Therapeutics, Inc. will develop and commercialize a new class of therapeutic RNAs for the treatment of infectious cancers.
- January 2022 The bivalent modified COVID-19 vaccine for Omicron BA.4/BA.5 will begin clinical trials, according to Pfizer Inc. and Biontech SE shows.
- American biotechnology company Ionis Pharmaceuticals, Inc. reported in January 2022 that tofersen, an experimental antipsychotic drug for the treatment of superoxide dismutase one amyotrophic lateral sclerosis, received FDA approval (SOD1-ALS).
Nucleic Acid Therapeutics Key Market Trends
- Increased Investment in Healthcare Services to Increase Market Growth: Increased investment in healthcare has also accelerated the pace of research into many diseases and illnesses. Research efforts to improve health facilities have increased due to the increasing prevalence of genetic abnormalities and chronic diseases in the population.
- Rise in the Incidence of Chronic Diseases: Rising rates of chronic diseases, including cancer and heart disease, and increasing costs of nucleic acid therapies are driving market growth. The Soros Economic Development Fund (SEDF) announced in May 2022 that it has invested $1 million 100 will support Kovacs efforts to increase COVID coverage -19 vaccination for low- and middle-income countries. Dollars will help for example, the Kingdom of Saudi Arabia (KSA) announced in October 2022 that it will spend $36.8 Billion or about 14.4% of the 2022 budget, on health promotion Consequently, investment in health about the rise in growth provided lucrative opportunities for market CAGR.
Nucleic Acid Therapeutics Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
The growth of the global nucleic acid therapeutics market is anticipated to be restrained due to lack of experience, technology and their high cost as developed and emerging economies play a dominant role in the research and development of new therapies, it appears that research will continue to expand this market in the future. High development costs, as well as expensive treatments and technologies were some of the major factors limiting industry expansion. Other factors driving the expansion of nucleic acid therapeutics market across the globe are, rapid attraction and speed to market, strong demand for products, and increasing focus of pharmaceutical companies in nucleic acid therapeutics.
| Report Metric | Details |
|---|---|
| Market size value in 2023 | USD 12.57 Billion |
| Market size value in 2032 | USD 18.05 Billion |
| Growth Rate | 4.1% |
| Base year | 2024 |
| Forecast period | 2025-2032 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Nucleic Acid Therapeutics Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Nucleic Acid Therapeutics Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Nucleic Acid Therapeutics Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Nucleic Acid Therapeutics Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Nucleic Acid Therapeutics Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Nucleic Acid Therapeutics Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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