Oligonucleotide Synthesis Market Size, Share, Growth Analysis, By Product(Oligonucleotide-based Drugs (Antisense Oligonucleotide-based drug, siRNA oligonucleotide-based drug, Other oligonucleotide-based drug), Synthesized Oligonucleotides (Primers), By Application(Therapeutic Applications (Disease Type (Neurological Disorders, Rare Diseases, Other Diseases)), Research Applications (PCR), By End User(Hospitals, Pharmaceutical & Biotechnology Companies, Diagnostic Laboratories, CROs and CMOs), By Region - Industry Forecast 2024-2031

Oligonucleotide Synthesis Market Drivers

Rising Application Scope of Oligonucleotides 

• Oligonucleotides play a key role in diagnostic tools such as PCR, qPCR, and next-generation sequencing (NGS) and demand for early diagnostics is increasing rapidly. This factor is projected to create new opportunities for oligonucleotide synthesis market growth going forward. 

Rising Demand for Gene Therapies 

• Oligonucleotides are essential in gene therapies, CRISPR-based gene editing, and personalized medicine. As use and acceptance of gene therapies for the treatment of multiple indications increases, it is also expected to benefit oligonucleotide synthesis demand outlook as well.  

Restraints 

High Costs of Synthesis 

• Oligonucleotide synthesis can be expensive, especially for high-purity or complex oligos required for therapeutic applications. The cost of purification and quality control further adds to the financial burden, limiting accessibility for smaller biotech firms. 

Ethical and Safety Concerns of Gene Therapies 

• The use of oligonucleotides in gene-editing technologies such as CRISPR has sparked ethical debates and safety concerns, particularly regarding unintended genetic modifications or long-term effects. These concerns may slow the adoption of some oligonucleotide-based applications.