USD 619.56 million
Peptide Synthesis Market Size, Share, Growth Analysis, By Product (Equipment, Peptide Synthesizers), By Technology (Solid Phase Peptide Synthesis, Liquid Phase Peptide Synthesis), By Application (Personalized Therapeutics, Cancer, Metabolic), By End-use, By Region - Industry Forecast 2024-2031.
Report ID:
SQMIG35H2313 |
Region:
Global |
Published Date: November, 2024
Pages:
162
|Tables:
119
|Figures:
70
Peptide Synthesis Market Insights
Global Peptide Synthesis Market size was valued at USD 619.56 million in 2022 and is poised to grow from USD 700.11 million in 2023 to USD 1861.20 million by 2031, growing at a CAGR of 13.0% during the forecast period (2024-2031).
Peptides serve as signaling molecules that interact with specific receptors located on the cell membrane, initiating intracellular responses that regulate various physiological functions and metabolic processes. In recent years, peptides have gained prominence as potential therapeutic agents due to their improved metabolic stability, specificity for biological targets, and greater binding affinity. It is crucial to recognize that peptide-based therapies differ significantly from small molecule drugs and biologics in aspects such as pharmacological research, analytical and process development, impurity analysis, and structural recognition. The peptide synthesis market has experienced substantial growth in recent years, driven by the rising interest in peptide therapeutics.
Demand for peptide synthesis has increased significantly in the past decade and the approval of peptide-based diagnosis therapy solution has witnessed a spike post pandemic. Presently, more than 80 peptide therapeutics have received approval in various regions worldwide for the treatment of numerous chronic conditions, including cancer, chronic pain, diabetes, HIV, multiple sclerosis, and osteoporosis. Furthermore, since 2015, over 630 clinical trials have been actively undertaken to assess the therapeutic efficacy of peptide-based treatments.
Market snapshot - 2024-2031
Global Market Size
Largest Segment
Pharmaceutical & Biotechnology companies
Fastest Growth
Services
Growth Rate
13.0%
Global Peptide Synthesis Market ($ Bn)
Country Share for North America Region (%)
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Peptide Synthesis Market Segmental Analysis
Global Peptide Synthesis Market is segmented by Product & Services, Technology, end user and region. Based on Product & Services, the market is segmented into Reagents, Equipment, Services. Based on Technology, the market is segmented into Solid-Phase Peptide Synthesis, Solution-Phase Peptide Synthesis, Hybrid & Recombinant Technology. Based on end user, the market is segmented into Pharmaceutical & Biotechnology companies, CDMOs & CROs, Academic & Research Institutes. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & and Africa.
Analysis by Application
Based on application, the market is segmented into personalized therapeutics, cancer, metabolic, and cardiovascular disorder. The personalized therapeutics segment is dominating the peptide synthesis market with the largest market revenue share. Demand for personalized therapeutic is significantly high due to its extensive treatment of both chronic and non-chronic disease. The demand for personalized therapeutic increased significantly during the pandemic as peptide-based diagnostics and treatment was prevalent. Personalized solutions and personalized medicines have gained significant acceptance in the past couple of years as healthcare expenditure and the need for personalized treatment is on the rise. In addition, many insurance companies are also providing coverage for peptide-based therapeutics solutions, which is also driving market demand.
The cardiovascular disease application segment is expected to witness higher growth during the forecast period. Cardiovascular disease is one of the most prevalent diseases among the adult population and the largest cause of death. In 2021 cardiovascular disease caused more than 20 million deaths globally and accounted for almost one third of all deaths annually. Longer working hours, sedentary lifestyle, lack of sleep and poor diets are some of the major factors causing cardiovascular diseases. Peptide base biomarkers and therapeutic agents are being widely used in the diagnostic and prevention of cardiovascular disease. Vasoactive peptides are the most used peptides used in the modulation of cardiovascular disease.
Analysis by End-use
In terms of end-use the demand for peptide synthesis is segmented into pharmaceutical & biotechnology companies, contract research organizations, and academic & research institutes. The demand for peptide systems is the largest for pharmaceutical & biotechnology. The financial resources at the disposal of big pharma and biotech companies have increased steadily in the past decade. As a result, these companies have access to labs, cutting edge technology, and infrastructure is significantly high. In addition, the adoption of technology among pharmaceutical and biotechnology companies has also increase post pandemic and the use of peptide for imaging and diagnosis is also growing considerably and this trend is expected to continue during the forecast.
The demand for peptide synthesis is expected to grow the fastest for contract research organization end-use, during the forecast period. The number of contract research organizations has grown substantially in the developed economies and in the Asia-Pacific countries. Availability of skilled resources and funding is growing for contract research organizations. In addition, the market has witnessed a high degree of collaboration between the big pharma companies, government agencies and the contract research organization are boosting the demand for this end-use segment. The collaborations are also increasing the funding available at the disposable of the contract research organizations.
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Peptide Synthesis Market Regional Insights
North America is dominating the global peptide synthesis market due to higher healthcare expenditure and developed healthcare service offerings. North America is home to some of the largest pharmaceutical companies in the world. These players are investing significantly in R&D with the cumulative R&D cost of the pharmaceutical companies in the US accounting to more than USD 95 billion in 2023. The increasing prevalence of chronic diseases in North America is also increasing the demand for peptide synthesis in the region. In the US, more than half of the adult population was reported to suffer from at least one chronic disease.
Demand for peptide synthesis is expected to grow the fastest in the Asia Pacific region. Asia Pacific region is the hub of contract manufacturing for pharmaceutical companies. Developing companies in the region such as China and India are investing significantly on providing facility and infrastructure for contract manufacturing. In addition, availability of trained human resources and the cheaper cost involved in approval and development of peptide synthesis is expected to fuel the demand for market during the forecast period. Growing healthcare budget and improving healthcare insurance coverage in developing economies in the region is also driving the end use demand.
Global Peptide Synthesis Market Market By Geography
- Largest
- Fastest
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Peptide Synthesis Market Dynamics
Drivers
Growing Demand for Imaging Based Diagnosis
- Imaging technology demand is growing substantially for accurate diagnosis of chronic diseases. Peptide synthesis market was valued at more than USD 30 billion in 2023. Use of biosensors and biomarkers for both invasive and non-invasive diagnosis is also very prevalent. Peptide based biosensors and biomarkers are experiencing massive demand growth fueling the market for peptide synthesis.
Increasing Acceptance of Personalized Medicine and Therapeutics
- Healthcare expenditure is increasing significantly in developed economies in North America and Europe. Due to the higher healthcare expenditure, the acceptance of more expensive alternate treatments such as personalized medicine is growing. Peptide based personalized medicine and therapeutics solutions are expected to gain momentum and drive the market demand during the forecast period.
Restraints
Lack of Standardization
- Pharmaceutical companies are spending significant resources on the development of peptide based therapeutic products, but the manufacturing is predominantly managed by contract manufacturing companies. Most of these contract manufacturing companies operate out of developed economies due to the low cost of production and does to adhere to the standardization guidelines or to the safety standards.
Strict Regulatory Framework
- Pharmaceutical companies on average spent an upwards of USD 50 million on development, clinical trial and approval process for a drug or therapeutic solution as the regulations are very strict and adhering to those is cost intensive. This has caused an entry barrier to many companies, and peptide-based solutions have become expensive for the end users.
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Peptide Synthesis Market Competitive Landscape
Peptide synthesis is a capital extensive business with a high entry barrier in terms of regulations and approvals. The market is dominated by major global players with many contract manufacturing companies expanding their operations in developing regions due to the low production cost advantages. Companies are spending significant resources on development and approval of new peptide based diagnostic and therapeutic products. Hence R&D initiatives and technology collaborations are the key business strategies witnessed in the market.
Top Player’s Company Profile
- MERCK KGAA
- THERMO FISHER SCIENTIFIC
- GENSCRIPT BIOTECH CORPORATION
- BACHEM HOLDING AG
- KANEKA CORPORATION
- BIOTAGE AB
- SYNGENE INTERNATIONAL LIMITED
- MESA LABORATORIES, INC.
- CEM CORPORATION
- PROTEOGENIX
- BIO-SYNTHESIS INC.
- DALTON PHARMA SERVICES
- AAPPTEC
- VIVITIDE
- ANYGEN CO., LTD.
- ADVANCED CHEMTECH
- LUXEMBOURG BIO TECHNOLOGIES LTD.
- JPT PEPTIDE TECHNOLOGIES GMBH
- AMBIOPHARM INC.
- AURIGENE PHARMACEUTICAL SERVICES LTD
Recent Developments
- In July 2023, Merch completed the acquisition of Asymchem. Asymchem is a US based contract manufacturer of pharmaceutical solutions including peptide solutions.
- In June 2023, Merck's partnered with IRBM, an innovative contract manufacturing organization. This partnership will help IRBM develop and manufacture peptide for therapeutic application outside US and Canada.
- In May 2023, PolyPeptide Group entered into an agreement with Numaferm. Numaferm is a biotechnology company, and this partnership will help the companies develop peptide manufacturing process for peptide based therapeutic application.
Peptide Synthesis Key Market Trends
- Substantial Growth in Pharmaceutical Industry: Pharmaceutical industry demand is increasing steadily, and R&D spending is increasing at an even higher growth rate. According to a survey conducted by the US Censos Bureau in 2020, expenditure on pharmaceutical R&D has increased by more than 25% in the past decade. This is providing more budget for development of peptide synthesis solutions and processes.
- Rise in the Peptide Based Therapeutics Demand during Pandemic: Peptide based therapeutics witness an uptick in demand during the pandemic due to its use for the diagnosis and treatment of Covid-19. Large number of pharmaceutical companies ramped up the development of new peptide therapeutics products and as a result number of peptides receiving FDA approvals during and post pandemic increased significantly.
Peptide Synthesis Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
As per SkyQuest analysis, the global peptide synthesis market is extremely opportunistic and competitive due to higher growth potential in terms of technology and product development. Peptide synthesis is a capital extensive market with major players investing significant resources in R&D and FDA approvals. The developing economies are investing more in contract manufacturing of peptide-based solutions.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 619.56 million |
| Market size value in 2031 | USD 1861.20 million |
| Growth Rate | 13.0% |
| Base year | 2023 |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Million |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
|
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Peptide Synthesis Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Peptide Synthesis Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Peptide Synthesis Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Peptide Synthesis Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Peptide Synthesis Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Peptide Synthesis Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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