USD 8.45 billion
Protein Purification and Isolation Market Size, Share, Growth Analysis, By Type(Instruments, and Kits and Reagents), By End-user(Pharmaceutical and Biotechnology Companies, Academic and Research Institutes, Contract Research Organizations (CROs), and Others), By Technique(Chromatography, Electrophoresis, Western Blotting, Precipitation), By Region - Industry Forecast 2024-2031
Report ID:
SQMIG35H2093 |
Region:
Global |
Published Date: March, 2024
Pages:
219
|Tables:
93
|Figures:
76
Protein Purification and Isolation Market Insights
Global Protein Purification and Isolation Market size was valued at USD 8.45 billion in 2022 and is poised to grow from USD 9.37 billion in 2023 to USD 21.35 billion by 2031, growing at a CAGR of 10.85% during the forecast period (2024-2031).
The global protein purification and isolation market is experiencing growth due to increasing research efforts in the pharmaceutical and biotechnology sectors for the development of innovative drugs. This surge in research activities is driving the demand for protein purification and isolation techniques. Additionally, pharmaceutical manufacturers are making substantial investments in research and development, further fueling market growth. These techniques are essential for separating, concentrating, stabilizing, and removing contaminants such as endotoxins, viruses, and nucleic acids during protein research. They play a crucial role in determining the function, structure, and interactions of proteins. Various methods are regularly employed for protein purification and separation, including affinity chromatography, immunoprecipitation, proteomics, and enzyme assays. However, increased government funding for research and development has facilitated market recovery, and it is expected to grow steadily in the forecast period. Governments worldwide are increasingly investing in research and development and implementing initiatives to promote the growth of the pharmaceutical and biotechnology markets. They provide additional benefits through tax incentives, grants, and investment-friendly regulations. The pharmaceutical industry is particularly lucrative for protein purification and isolation solutions, given the significant investments in developing biomarker-specific molecules. Accurate isolation of proteins with a substantial amount of purified substrate is critical during the preclinical drug development phase.
Ongoing technological advancements are also driving the market for protein purification and isolation solutions. Magnetic and protein beads, as well as ligand tagging systems, are gaining preference over traditional methods like agarose beads and other resins. The adoption of automated analyzers is on the rise, further boosting the demand for purification and isolation solutions. The increasing importance of discovering novel ligands, such as protein-based therapeutic compounds, is a significant factor contributing to market expansion. Moreover, there is a growing demand for purification kits in rapid screening tests, a shift towards technologically advanced instrumentation, and the expansion of the proteomics market. However, challenges such as low acceptance rates of certain instruments, the difficulty of finding purification kits suitable for all purposes, and high tool costs hinder market growth. Nonetheless, the protein purification and isolation industry benefits from untapped growth markets and the increasing use of protein therapies.
US Protein Purification and Isolation Market is poised to grow at a sustainable CAGR for the next forecast year.
Market snapshot - 2024-2031
Global Market Size
Largest Segment
Instruments
Fastest Growth
Instruments
Growth Rate
10.85% CAGR
Global Protein Purification and Isolation Market ($ Bn)
Country Share for North America Region (%)
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Protein Purification and Isolation Market Segmental Analysis
Global Protein Purification and Isolation Market is segmented by type, end-user, technique and region. Based on type, the market can be segmented into instruments, and kits and reagents. Based on end-user, the market is segmented into pharmaceutical and biotechnology companies, academic and research institutes, contract research organizations (CROs), and others. Based on technique, the market is segmented into chromatography, electrophoresis, western blotting, precipitation, ultrafiltration and microfiltration, and others. Based on region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.
Protein Purification and Isolation Market Analysis by Type
By type, the market can be segmented into instruments, and kits and reagents. The Instruments segment holds a dominant position in the protein purification and isolation market. This segment comprises various equipment and instruments used for protein purification and isolation processes, including chromatography systems, centrifuges, electrophoresis systems, and filtration systems. The dominating position of the Instruments segment can be attributed to the increasing demand for technologically advanced and efficient instruments for protein purification and isolation. This is driven by the rising need for purified proteins in various research and development activities in the pharmaceutical, biotechnology, and academic sectors.
The Kits and Reagents segment is experiencing rapid growth within the protein purification and isolation market. This segment includes consumables and reagents required for protein purification and isolation processes, such as purification kits, resins, columns, and buffers. The Kits and Reagents segment is witnessing substantial growth due to several factors. Firstly, the increasing adoption of kits and reagents by researchers and scientists in academic and research institutes, as well as pharmaceutical and biotechnology companies, drives the demand. Secondly, the availability of ready-to-use kits and standardized reagents simplifies the protein purification and isolation process, saving time and effort.
Protein Purification and Isolation Market Analysis by End-user
By end-user, the market can be segmented into pharmaceutical and biotechnology companies, academic and research institutes, contract research organizations (CROs), and others. Pharmaceutical and biotechnology companies hold a dominating position in the protein purification and isolation market. These companies are involved in drug discovery, development, and production, and protein purification and isolation play a crucial role in their research and manufacturing processes. Pharmaceutical and biotechnology companies are the primary end-users of protein purification and isolation products. These companies invest heavily in research and development activities to discover and develop new drugs and therapies, driving the demand for protein purification and isolation technologies.
Contract Research Organizations (CROs) are experiencing rapid growth within the protein purification and isolation market. These specialized organizations provide protein purification and isolation services to pharmaceutical and biotechnology companies, academic institutions, and other research entities. The fastest growing segment is driven by the growing trend of outsourcing protein purification and isolation processes to CROs. Pharmaceutical and biotechnology companies, particularly smaller ones and startups, often rely on CROs to access specialized expertise and resources for protein purification and isolation. This enables them to focus on core drug discovery and development activities.
Global Protein Purification and Isolation Market By Type
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Protein Purification and Isolation Market Regional Insights
North America is the dominating region in the global protein purification and isolation market. The region's dominance can be attributed to several factors. Firstly, North America has a well-established and advanced healthcare infrastructure, which supports extensive research and development activities in the pharmaceutical and biotechnology sectors. The presence of major pharmaceutical companies and research institutions in the region further contributes to its dominance.
Asia Pacific is the fastest growing region in the global protein purification and isolation market. The region's rapid growth can be attributed to several factors. Firstly, Asia Pacific has a large population base, resulting in a high demand for improved healthcare and pharmaceutical products. The increasing prevalence of chronic diseases and the need for novel drugs drive the demand for protein purification and isolation techniques in the region.
Global Protein Purification and Isolation Market By Geography
- Largest
- Fastest
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Protein Purification and Isolation Market Dynamics
Protein Purification and Isolation MarketDrivers
Increasing demand for protein-based therapeutic compounds
- One significant driver of the global protein purification and isolation market is the increasing demand for protein-based therapeutic compounds. With advancements in biotechnology and a greater understanding of protein structures and functions, there is a growing emphasis on developing innovative protein-based drugs for various diseases. This rising significance of discovering novel ligands and the potential of protein therapies propel the demand for protein purification and isolation solutions, driving market expansion.
Protein Purification and Isolation Market Restraints
High cost associated with the tools and equipment
- One key restraint in the global protein purification and isolation market is the high cost associated with the tools and equipment used in the purification process. The sophisticated instruments and materials required for effective protein purification can be expensive, posing a financial challenge for smaller research laboratories and organizations with limited budgets. Additionally, maintaining purification kits that cater to diverse research purposes can be complex and costly. The high cost of tools and the difficulty in finding versatile purification kits hinder the growth potential of the market.
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Protein Purification and Isolation Market Competitive Landscape
The global protein purification and isolation market is characterized by intense competition among various companies. Market players focus on strategies such as mergers and acquisitions, collaborations, and product launches to gain a competitive edge. Ongoing technological advancements in protein purification and isolation techniques contribute to the competitive rivalry. Additionally, companies invest in research and development activities to develop innovative solutions and expand their product portfolios. Providing reliable and efficient purification solutions, maintaining regulatory compliance, and offering excellent customer support are vital factors for companies to establish a strong position in the market.
Protein Purification and Isolation Market Top Player’s Company Profiles
- GE Healthcare (US)
- Merck KGaA (Germany)
- Bio-Rad Laboratories (US)
- Agilent Technologies (US)
- Qiagen (Germany)
- BioVision Inc. (US)
- Promega Corporation (US)
- Abcam plc (UK)
- Takara Bio Inc. (Japan)
- Sartorius AG (Germany)
- PerkinElmer Inc. (US)
- Pall Corporation (US)
- Waters Corporation (US)
- Sigma-Aldrich Corporation (US)
- Miltenyi Biotec (Germany)
- Roche Diagnostics (Switzerland)
- BioLegend, Inc. (US)
- Lonza Group Ltd. (Switzerland)
- Novus Biologicals, LLC (US)
Protein Purification and Isolation Market Recent Developments
- In June 2023, PerkinElmer acquired Aurora Biotechnologies, a provider of protein expression and purification technologies, to enhance its protein research and analysis capabilities.
- In May 2023, Bio-Rad Laboratories launched the NGC Chromatography System, a compact and flexible system for protein purification in research and process development.
- In March 2023, Avantor, Inc. acquired Porton Biopharma Limited, a manufacturer of biopharmaceutical products, to expand its capabilities in the bioprocessing and protein purification market.
- In February 2023, Waters Corporation and Bruker Corporation formed a collaboration to develop mass spectrometry-based solutions for protein characterization and analysis.
- In January 2023, Sartorius announced the acquisition of a majority stake in Novasep's chromatography process equipment division, expanding its chromatography portfolio and strengthening its presence in the purification market.
Protein Purification and Isolation Key Market Trends
- One key market trend in the global protein purification and isolation market is the increasing adoption of automated analyzers. Automated systems offer advantages such as higher throughput, improved precision, and reduced manual labor. These analyzers streamline the purification process, enabling efficient protein isolation and minimizing human error. The rising demand for high-throughput purification methods in research laboratories and pharmaceutical companies is driving the trend of automated analyzers. This trend not only enhances workflow efficiency but also contributes to the overall growth and advancement of the protein purification and isolation market.
Protein Purification and Isolation Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
According to our global protein purification and isolation market analysis, the market is witnessing growth driven by factors such as growing research in the pharmaceutical and biotechnology sectors, increased investments in R&D, and government funding for research initiatives. Protein purification and isolation techniques play a vital role in separating, concentrating, and eliminating contaminants during protein research. North America dominates the market, benefiting from advanced healthcare infrastructure and significant investments in R&D. Asia Pacific is the fastest growing region due to its large population, increasing pharmaceutical industry, and rising investments in research and development. However, challenges such as high tool costs and the difficulty of finding versatile purification kits pose restraints to market growth. The trend of automated analyzers is gaining traction, improving workflow efficiency in protein purification processes.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 8.45 billion |
| Market size value in 2031 | USD 21.35 billion |
| Growth Rate | 10.85% |
| Base year | 2023 |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
|
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Protein Purification and Isolation Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Protein Purification and Isolation Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Protein Purification and Isolation Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Protein Purification and Isolation Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Protein Purification and Isolation Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Protein Purification and Isolation Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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