Recombinant DNA Technology Market Size, Share, Growth Analysis, By Product(Medical (Therapeutic Agent, Human Protein, Vaccines), Non-Medical (Biotech Crops), By Component(Expression System (Mammalian, Bacteria, Yeast, Baculovirus/Insect)), By Application(Health and disease (Human, Animal), Food and Agriculture, Environment), By End User(Pharmaceutical and biotechnology companies, Research institutes, Others), By Region - Industry Forecast 2024-2031


Report ID: SQMIG35H2067 | Region: Global | Published Date: February, 2024
Pages: 242 |Tables: 124 |Figures: 77

Recombinant DNA Technology Market Insights

Recombinant DNA Technology Market size was valued at USD 141.96 billion in 2019 and is poised to grow from USD 152.79 billion in 2023 to USD 274.52 billion by 2031, growing at a CAGR of 7.6% in the forecast period (2024-2031).

The development of recombinant DNA (rDNA) technology has given scientists unprecedented control over genetic data. It is now used in a wide range of applications, including conventional and non-traditional. Without the aid of human donors, recombinant medications and therapeutics have indeed been produced with remarkable success over the past few years.

The commercial success of genetic modification insulin as a diabetes treatment is the classic example of this achievement. The biotech and pharmaceutical industries are exploring how rDNA techniques might be used in various facets of illness management. This is primarily done to combat the rising costs associated with chronic illnesses and stay up with the growing market for therapeutics.

Furthermore, by enabling it possible to produce a recombinant DNA molecule, the gradual development of rDNA techniques has opened up new avenues for improving biopharmaceutical development. The adoption of this technology is expected to be fueled by the presence of a strong biopharmaceuticals pipeline, especially the pipeline for recombinant proteins. The growth of the market is due primarily to the development of recombinant products using rDNA techniques in conjunction with CRISPR/Cas9 nuclease, ZFN, and TALEN enabling simple & precise genome editing with no restriction by organisms. Several review studies carried out by scientists have shown the efficacy of rDNA technology.

The growth of GM crop acreage globally is evidence of this technology's success in the agricultural and food sectors. Its use in other unusual applications, such as the production of biofuel and biopesticides to solve environmental issues, has indeed been inspired by this. Because of the ethical issues in numerous applications, such as gene therapy, the use of this technology has been contentious. Technology and morality have varied, discipline-specific concerns in the diverse fields of agriculture, the environment, and medicine.

US Recombinant DNA Technology Market is poised to grow at a sustainable CAGR for the next forecast year.

Market Snapshot - 2024-2031

Global Market Size

USD 141.96 billion

Largest Segment

Health and disease

Fastest Growth

Health and disease

Growth Rate

7.6% CAGR

Global Recombinant DNA Technology Market ($ Bn)
Country Share for North America Region (%)

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Recombinant DNA Technology Market Segmental Analysis

Global Recombinant DNA Technology Market is segmented based on Product, Component, Application, End User, and region. Based on Product, the market is segmented into Medical (Therapeutic Agent, Human Protein, Vaccines), Non-Medical (Biotech Crops, Specialty Chemicals, Others. Based on Component the market is segmented into Expression System (Mammalian, Bacteria, Yeast, Baculovirus/Insect), Cloning Vector. Based on Application, the market is segmented into Health and disease (Human, Animal), Food and Agriculture, Environment, Others. Based on End User, the market is segmented into Pharmaceutical and biotechnology companies, Research institutes, Others. Based on region, the global market is segmented into North America, Europe, Asia-Pacific, South America, and MEA.

Recombinant DNA Technology Market Analysis by Application

The health and disease application segment, which has historically dominated the market and is anticipated to increase in the next years, is predicted to have the greatest market share in the years to come. As there has been a high demand for a variety of goods produced using this technology in this industry, the sector is anticipated to grow favorably even in the upcoming years. These products were created to cure various human ailments and provide immunizations for them. Moreover, there has been an upsurge in the production of replacement enzymes using this technology.

This technology is used to cure a wide range of animals in addition to avoiding and treating many diseases that affect humans. The agriculture industry is under a lot of strain as a result of population expansion in both developed and developing nations. Farmers are using this technology in order to boost production and create good harvests. The agriculture and food sectors have seen great success with the application of this recombination process. The quality and quantity of the produce, which is expected to satisfy the demands of the expanding population, have awesome things to the use of this technology in the food and agriculture industry. The usage of this technology to produce biofuels is expected to rise significantly in the coming future because of the high demand for these fuels.

Recombinant DNA Technology Market Analysis by Component

Recognized as the two main components of this technology are the expression system and cloning vector. Due to ongoing research and development for effective protein expression and for its further large-scale isolation, expression systems accounted for the biggest share. Mammalian, bacterial, insect, and yeast expression systems are commonly employed. The growth of cell lines like HEK293 and Chinese Hamster Ovarian (CHO) has helped explain why mammalian expression systems account for such a large segment of the market.

Additionally, it is expected that the adoption of plant expression systems for the creation of GM products in the upcoming years will be driven by current research investigations to investigate the potential of plants as an expression system. It is recognized that cloning vectors are the basis for the production of DNA inserts.

Global Recombinant DNA Technology Market By Application

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Recombinant DNA Technology Market Regional Insights

North America dominated the global market. The largest portion of the North American continent can be ascribed to the country's high concentration of biopharmaceutical manufacturing companies. Development aid has also been aided by the existence of powerful regulatory bodies that can keep an eye on the numerous ethical and scientific issues raised by the use of technology.

The availability of cost-effective manufacturing facilities in Asian countries such as China have attracted the attention of multinational corporations planning to shift their operations to this region. On a per capita basis, Japan is also one of the leading importers of food and feed made with modern biotechnology. In Japan, the GE agriculture regulatory framework is becoming more effective. In addition, there are no significant trade restrictions in place in Japan that would obstruct the export of GE items from Western countries. As a result, during the forecast period, Asia-Pacific is expected to have the fastest market growth in the region.

Global Recombinant DNA Technology Market By Region
  • Largest
  • Fastest

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Recombinant DNA Technology Market Dynamics

Recombinant DNA Technology Market Drivers

Increased Strategic Collaboration Among Industry Players

  • During the forecast period, market expansion is expected to be driven by increasing strategic collaborations between leading market players to advance recombinant DNA technology. To create novel therapeutics based on recombinant DNA technologies, key market players strategically work with large biopharmaceutical companies and research institutions. Such market-wide strategic alliances are anticipated to spur market expansion soon.

Increasing Technological Advancements in R&D Projects to Fuel Market Expansion

  • The production of fresh products is aided by the boom in technological advancements. The Recombinant DNA Technology Market is also growing as a result of increased research and development efforts for the treatment of severe diseases like cancer, diabetes, and other immunodeficiency disorders. The confluence of technology and medicine is making it possible to treat diseases by replacing faulty or sick genes in a person's blood with new, healthy ones. Moreover, the development of gene therapy as a result of recombinant technology improvements has been employed to cure hereditary illnesses. This will support the global recombinant DNA technology market growth during the forecast period.

Recombinant DNA Technology Market Restraints

High price and side effects of gene therapy

  • Market growth is being restricted by the expensive nature of gene therapy as well as side effects like Cytokine Release Syndrome (CRS) or neurotoxicity’s. The rise of the market is also anticipated to be constrained during the projection period by ethical, legal, and scientific restrictions related to gene therapy.

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Recombinant DNA Technology Market Competitive Landscape

These participants are working together in alliances to provide their services in a variety of life science fields. Also, as a realistic tactic to maintain competitiveness in the market, companies are growing constantly their manufacturing facilities.

Recombinant DNA Technology Market Top Player’s Company Profiles

  • Thermo Fisher Scientific Inc.
  • Merck KGaA
  • GenScript Biotech Corporation
  • Horizon Discovery Group plc
  • Lonza Group AG
  • Novartis AG
  • Integrated DNA Technologies, Inc.
  • Genentech, Inc.
  • Amgen Inc.
  • Biogen Inc.
  • Illumina, Inc.
  • Agilent Technologies, Inc.
  • Roche Holding AG
  • Qiagen N.V.
  • Eurofins Scientific SE
  • Takara Bio Inc.
  • Celgene Corporation
  • Bio-Rad Laboratories, Inc.
  • Gensight Biologics S.A.
  • Promega Corporation

Recombinant DNA Technology Market Recent Developments

  • In March 2022, For the purpose of preventing infection by any known subtype of the hepatitis B virus (HBV) in people 18 years of age and older, VBI Vaccines Inc. recombinant hepatitis B vaccine PreHevbrio was first given to Americans.
  • In February 2022, The European Medicines Agency's Committee for Medicinal Products for Human Use gave the 3-antigen hepatitis B (HBV) vaccine, marketed under the trade name PreHevbri, its seal of approval for adults seeking active immunization against infection brought on by any of the known subtypes of the hepatitis B virus.

Recombinant DNA Technology Key Market Trends

  • A large amount of public acceptance is now being acquired for the development of genetically modified crops in agriculture to increase yield and resistance to herbicides or pesticides. The genetically modified tomato CGN-89564-2 was among the first commercially available genetically engineered crop items to be granted a license for human consumption. Also dependent on DNA molecular marker technologies are the identification, evaluation, mining, and innovation of plant germplasm resources. Thus, it is expected that increasing RDT being used in food and agriculture will drive the original study segment's growth. Research on genetically modified organisms (GMOs), such as that on microorganisms that are regarded as bio degraders and generators of clean fuel, helps a wide range of additional sectors. Numerous human and plant illnesses are treated with genetically modified vaccinations. Recombinant DNA technology has opened up a variety of potential opportunities and prospects for creating a variety of therapeutic items with immediate effects in medical genetics and biomedicine. This is achieved by altering microbes, animals, and plants to produce medically valuable compounds.

Recombinant DNA Technology Market SkyQuest Analysis

SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates and Analyses the Data collected by means of Primary Exploratory Research backed by the robust Secondary Desk research.

According to our global recombinant DNA technology market analysis, we found that the market is essential for improving health conditions, especially through the development of new pharmaceuticals and vaccines. Moreover, novel therapeutic modalities, monitoring tools, and diagnostic kits are being developed to enhance treatment tactics. The study of genetically modified organisms (GMOs) has also helped many other industries, including the production of clean fuel and microbial degradation by microorganisms. Vaccines made from genetic material are being developed to treat a variety of human and plant ailments. By altering microorganisms, animals, and plants to generate medications, recombinant DNA technology has provided a variety of potential innovation prospects for the creation of a broad range of therapeutic products with immediate benefit in medical genetics and biomedicine.

Report Metric Details
Market size value in 2023 USD 141.96 billion
Market size value in 2031 USD 274.52 billion
Growth Rate 7.6%
Forecast period 2024-2031
Forecast Unit (Value) USD Billion
Segments covered
  • Product
    • Medical (Therapeutic Agent, Human Protein, Vaccines), Non-Medical (Biotech Crops, Specialty Chemicals, Others.
  • Component
    • Expression System (Mammalian, Bacteria, Yeast, Baculovirus/Insect), Cloning Vector
  • Application
    • Health and disease (Human, Animal), Food and Agriculture, Environment, Others
  • End User
    • Pharmaceutical and biotechnology companies, Research institutes, Others
Regions covered North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA)
Companies covered
  • Thermo Fisher Scientific Inc.
  • Merck KGaA
  • GenScript Biotech Corporation
  • Horizon Discovery Group plc
  • Lonza Group AG
  • Novartis AG
  • Integrated DNA Technologies, Inc.
  • Genentech, Inc.
  • Amgen Inc.
  • Biogen Inc.
  • Illumina, Inc.
  • Agilent Technologies, Inc.
  • Roche Holding AG
  • Qiagen N.V.
  • Eurofins Scientific SE
  • Takara Bio Inc.
  • Celgene Corporation
  • Bio-Rad Laboratories, Inc.
  • Gensight Biologics S.A.
  • Promega Corporation
Customization scope

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  • Market dynamics & outlook
  • Region

Historical Year 2019

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Table Of Content

Executive Summary

Market overview

  • Exhibit: Executive Summary – Chart on Market Overview
  • Exhibit: Executive Summary – Data Table on Market Overview
  • Exhibit: Executive Summary – Chart on Recombinant DNA Technology Market Characteristics
  • Exhibit: Executive Summary – Chart on Market by Geography
  • Exhibit: Executive Summary – Chart on Market Segmentation
  • Exhibit: Executive Summary – Chart on Incremental Growth
  • Exhibit: Executive Summary – Data Table on Incremental Growth
  • Exhibit: Executive Summary – Chart on Vendor Market Positioning

Parent Market Analysis

Market overview

Market size

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • SWOT Analysis

KEY MARKET INSIGHTS

  • Technology Analysis
    • (Exhibit: Data Table: Name of technology and details)
  • Pricing Analysis
    • (Exhibit: Data Table: Name of technology and pricing details)
  • Supply Chain Analysis
    • (Exhibit: Detailed Supply Chain Presentation)
  • Value Chain Analysis
    • (Exhibit: Detailed Value Chain Presentation)
  • Ecosystem Of the Market
    • Exhibit: Parent Market Ecosystem Market Analysis
    • Exhibit: Market Characteristics of Parent Market
  • IP Analysis
    • (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
  • Trade Analysis
    • (Exhibit: Data Table: Import and Export data details)
  • Startup Analysis
    • (Exhibit: Data Table: Emerging startups details)
  • Raw Material Analysis
    • (Exhibit: Data Table: Mapping of key raw materials)
  • Innovation Matrix
    • (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
  • Pipeline product Analysis
    • (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
  • Macroeconomic Indicators

COVID IMPACT

  • Introduction
  • Impact On Economy—scenario Assessment
    • Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
  • Revised Market Size
    • Exhibit: Data Table on Recombinant DNA Technology Market size and forecast 2021-2027 ($ million)
  • Impact Of COVID On Key Segments
    • Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
  • COVID Strategies By Company
    • Exhibit: Analysis on key strategies adopted by companies

MARKET DYNAMICS & OUTLOOK

  • Market Dynamics
    • Exhibit: Impact analysis of DROC, 2021
      • Drivers
      • Opportunities
      • Restraints
      • Challenges
  • Regulatory Landscape
    • Exhibit: Data Table on regulation from different region
  • SWOT Analysis
  • Porters Analysis
    • Competitive rivalry
      • Exhibit: Competitive rivalry Impact of key factors, 2021
    • Threat of substitute products
      • Exhibit: Threat of Substitute Products Impact of key factors, 2021
    • Bargaining power of buyers
      • Exhibit: buyers bargaining power Impact of key factors, 2021
    • Threat of new entrants
      • Exhibit: Threat of new entrants Impact of key factors, 2021
    • Bargaining power of suppliers
      • Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
  • Skyquest special insights on future disruptions
    • Political Impact
    • Economic impact
    • Social Impact
    • Technical Impact
    • Environmental Impact
    • Legal Impact

Market Size by Region

  • Chart on Market share by geography 2021-2027 (%)
  • Data Table on Market share by geography 2021-2027(%)
  • North America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • USA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Canada
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Europe
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Germany
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Spain
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • France
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • UK
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Europe
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Asia Pacific
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • China
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • India
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Japan
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Korea
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of Asia Pacific
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Latin America
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • Brazil
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of South America
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
  • Middle East & Africa (MEA)
    • Chart on Market share by country 2021-2027 (%)
    • Data Table on Market share by country 2021-2027(%)
    • GCC Countries
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • South Africa
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)
    • Rest of MEA
      • Exhibit: Chart on Market share 2021-2027 (%)
      • Exhibit: Market size and forecast 2021-2027 ($ million)

KEY COMPANY PROFILES

  • Competitive Landscape
    • Total number of companies covered
      • Exhibit: companies covered in the report, 2021
    • Top companies market positioning
      • Exhibit: company positioning matrix, 2021
    • Top companies market Share
      • Exhibit: Pie chart analysis on company market share, 2021(%)

Methodology

For the Recombinant DNA Technology Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:

1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.

2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Recombinant DNA Technology Market.

3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.

4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.

Analyst Support

Customization Options

With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Recombinant DNA Technology Market:

Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.

Regional Analysis: Further analysis of the Recombinant DNA Technology Market for additional countries.

Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.

Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.

Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.

Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.

Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.

Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.

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FAQs

Recombinant DNA Technology Market size was valued at USD 141.96 billion in 2019 and is poised to grow from USD 152.79 billion in 2023 to USD 274.52 billion by 2031, growing at a CAGR of 7.6% in the forecast period (2024-2031).

These participants are working together in alliances to provide their services in a variety of life science fields. Also, as a realistic tactic to maintain competitiveness in the market, companies are growing constantly their manufacturing facilities. 'Thermo Fisher Scientific Inc.', 'Merck KGaA', 'GenScript Biotech Corporation', 'Horizon Discovery Group plc', 'Lonza Group AG', 'Novartis AG', 'Integrated DNA Technologies, Inc.', 'Genentech, Inc.', 'Amgen Inc.', 'Biogen Inc.', 'Illumina, Inc.', 'Agilent Technologies, Inc.', 'Roche Holding AG', 'Qiagen N.V.', 'Eurofins Scientific SE', 'Takara Bio Inc.', 'Celgene Corporation', 'Bio-Rad Laboratories, Inc.', 'Gensight Biologics S.A.', 'Promega Corporation'

During the forecast period, market expansion is expected to be driven by increasing strategic collaborations between leading market players to advance recombinant DNA technology. To create novel therapeutics based on recombinant DNA technologies, key market players strategically work with large biopharmaceutical companies and research institutions. Such market-wide strategic alliances are anticipated to spur market expansion soon.

A large amount of public acceptance is now being acquired for the development of genetically modified crops in agriculture to increase yield and resistance to herbicides or pesticides. The genetically modified tomato CGN-89564-2 was among the first commercially available genetically engineered crop items to be granted a license for human consumption. Also dependent on DNA molecular marker technologies are the identification, evaluation, mining, and innovation of plant germplasm resources. Thus, it is expected that increasing RDT being used in food and agriculture will drive the original study segment's growth. Research on genetically modified organisms (GMOs), such as that on microorganisms that are regarded as bio degraders and generators of clean fuel, helps a wide range of additional sectors. Numerous human and plant illnesses are treated with genetically modified vaccinations. Recombinant DNA technology has opened up a variety of potential opportunities and prospects for creating a variety of therapeutic items with immediate effects in medical genetics and biomedicine. This is achieved by altering microbes, animals, and plants to produce medically valuable compounds.

North America dominated the market. The largest portion of the North American continent can be ascribed to the country's high concentration of biopharmaceutical manufacturing companies. Development aid has also been aided by the existence of powerful regulatory bodies that can keep an eye on the numerous ethical and scientific issues raised by the use of technology.

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