T-cell Therapy Market
Report ID: SQMIG35H2210
T-cell Therapy Market Size, Share, Growth Analysis, By Modality(Research, Commercialized), By Type(CAR T-cell Therapy, T Cell Receptor (TCR)-based, Tumor Infiltrating Lymphocytes (TIL)-based), By Indication(Hematologic Malignancies, Solid Tumors, others), By End User, By Region - Industry Forecast 2024-2031
Report ID:
SQMIG35H2210 |
Region:
Global |
Published Date: February, 2024
Pages:
285
|Tables:
117
|Figures:
78
T-cell Therapy Market Insights
Global T-Cell Therapy Market size was valued at USD 2.83 billion in 2022 and is poised to grow from USD 3.83 billion in 2023 to USD 43.0 billion by 2031, growing at a CAGR of 35.3% during the forecast period (2024-2031).
One of the main causes of mortality across the globe is cancer. It is predicted that by the end of 2040, there will be an additional 27.5 million cancer cases worldwide, placing a significant financial, emotional, and physical burden on those who are affected, their families, communities, and national health systems. Although there are several treatments available to slow the disease's growth and prevent cancer cells from spreading throughout the body, achieving a long-lasting remission is challenging.
In this regard, immunotherapies, a more recent addition to the spectrum of anticancer treatments, have shown a lot of promise. T-cell therapies (more specifically, CAR-T therapies, TCR therapies, and TIL therapies) have emerged as a promising option among the current efforts made to develop more targeted anti-cancer therapies. This is due to their capacity to eradicate tumor cells from the body with a minimum of treatment-related side effects. Globally, cancer treatment has been transformed by this very effective and promising type of T-cell therapy, which uses the adaptable effector apparatus of the human immune system. This emerging therapeutic area is on its way to become one of the highest valuable markets within the biopharmaceutical sector, given the steadily rising number of cell treatments being developed and introduced.
US T-cell Therapy Market is poised to grow at a sustainable CAGR for the next forecast year.
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T-cell Therapy Market Segmental Analysis
Global T-Cell Therapy Market is segmented by therapy type, modality, indication, end-user and region. Based on therapy type, the market is segmented into CAR T-cell therapy, tumor-infiltrating lymphocytes (TIL) therapy and t cell receptor (TCR)-based therapy. Based on modality, the market is segmented into research use and clinical use. Based on indication, the market is segmented into hematologic malignancies, solid tumors, infectious diseases and autoimmune diseases. Based on end-user, the market is segmented into hospitals, cancer treatment centers and research institutes. Based on region, the market is segmented into North America, Europe, Asia Pacific, Latin America and Middle East & Africa.
T-cell Therapy Market Analysis by Modality
The research segment accounted for the highest market share during 2021 and accounted for approximately 76% of revenue share of global revenue in 2021. This can be attributed to the high number of products in the clinical development phase. Many research institutions, like Mayo Clinic, are actively involved in running CAR-T treatment programmes, promoting the approach as a better way to control cancer. The shift in emphasis on accelerate the development of CAR-T treatments to broaden the therapeutic application landscape is the product of many operating companies working with research groups throughout the world.
Regulating organisations, on the other hand, are working hard to promote the commercial use of these treatments in clinical and hospital settings. The Centers for Medicare and Medicaid Services (CMS) has unveiled standards regarding CAR-T cell treatment payment and coverage. Due to this policy, the money received climbed to 65% of the entire cost. This would encourage a rise in commercial income.
T-cell Therapy Market Analysis by Type
The segment of CAR T-cell held the largest market share in 2021 and accounted for approximately 83% of revenue share of global revenue. This is because there are now an increasing number of clinical studies for CAR-T therapy, and important actors in this field are becoming more involved. Clinical studies for CAR-T therapy items are being conducted by a sizable number of new players and academic institutions for both the same and different indications, strengthening the segment's dominance. The use of CAR-T treatments in the treatment of different tumours has increased as a result of improvements in CAR-T therapy production. By overcoming obstacles like resistance and side effects, emerging strategies like second- and next-generation CAR-T immunotherapy may increase the creation of organic income.
In addition, T-cell receptor-based treatments, which have the potential to treat solid tumours, are ranked second globally. For the treatment of melanoma, this area is attracting a lot of interest.
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T-cell Therapy Market Regional Insights
North America held the largest market share of Global T cell therapy Market in 2021 and accounted for the largest revenue share of around 41% in 2021. Strong research, a thriving industry, and a significant number of clinical trials for T-cell treatments being carried out in the U.S. have all significantly aided in the region's market supremacy. Additionally, the market has grown significantly as a result of the rising number of regulatory approvals in the U.S. and Canada as well as the region's shifting reimbursement environment. Additionally, the expansion of the regional market is aided by the large number of medical facilities that provide CAR-T cell therapy.
Asia Pacific region is expected to witness the fastest growth rate during the forecast period with growing markets like China leading the way. China now boasts the most registered clinical trials for CAR-T therapies, making it a viable market for these treatments in recent years. Focused efforts on government spending and reforms in the region have ultimately led to tremendous development of the market.
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T-cell Therapy Market Dynamics
T-cell Therapy Market Driver
- Following the FDA's approval of Yescarta, Kymriah, and Tecartus, a number of businesses have switched from developing protein- and small-molecule-based therapeutics to adoptive therapies as their primary business model. The market for T-cell treatment has grown as a result of strategic expenditures made in this area by both public and commercial organisations.
- The effectiveness of CAR-T treatments is greatly influenced by the growing gene therapy business. Gene therapy is predicted to see steady increase as a result of rising investment levels. Additionally, T-cell-based mechanisms are frequently used in the cancer immunotherapy field due to a greater success rate, which further fuels the market's rise.
- Furthemore, the companies are pouring a lot of money into the research and development of CAR T-cell therapy, whether it be used alone or in conjunction with other treatments. The market for T-cell treatment will grow as a result of the recent expansion of the clinical trial landscape for different hematologic malignancies.
T-cell Therapy Market Restraint
- The significant ineffectiveness of CAR-T treatments to treat solid tumours and associated safety issues brought on by the highly immunosuppressive tumour microenvironment is restricting their market growth. As a result, operational players are working to put new strategies into place to address these issues and broaden the use in solid.
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T-cell Therapy Market Competitive Landscape
Global T cell therapy Market is fragmented and competitive due to the presence of major players. Companies are clamouring to invest in the creation of innovative CAR T-cell treatment due to the exponential increase in the use of precision medicine on a worldwide scale. To maintain a competitive edge and increase their market position in the worldwide Tcell therapy market, leading companies are increasingly focusing on implementing tactics such as adopting new technology, product developments, mergers and acquisitions, joint venture, alliances, and partnerships. In order to provide industries with the most effective and economical solutions, the major market players are also continually concentrating on R&D.
T-cell Therapy Market Top Player's Company Profiles
- Novartis (Switzerland)
- Gilead Sciences (USA)
- Bristol-Myers Squibb (USA)
- Kite Pharma (USA)
- Juno Therapeutics (USA)
- Adaptimmune (UK)
- Bluebird Bio (USA)
- Cellectis (France)
- Bellicum Pharmaceuticals (USA)
- Sangamo Therapeutics (USA)
- Atara Biotherapeutics (USA)
- Autolus Therapeutics (UK)
- Immatics (Germany)
- Allogene Therapeutics (USA)
- Mustang Bio (USA)
- Celyad Oncology (Belgium)
- Genocea Biosciences (USA)
- Iovance Biotherapeutics (USA)
T-cell Therapy Market Recent Developments
- In September 2022, Arsenal Biosciences, Inc. (ArsenalBio), a privately held firm that develops cutting-edge CAR T therapeutics for solid tumours and specialises in programmable cell therapy, today announced a multi-year partnership with Genentech, a member of the Roche Group. To find crucial success circuits in T cell-based therapeutics, the businesses will use ArsenalBio's patented technology for high-throughput screening and engineering of T cells.
- In September 2022, CRISPR Therapeutics, a biopharmaceutical company focused on developing revolutionary gene-based medicines for serious diseases, made the announced that The U.S. Food and Drug Administration (FDA) has designated CTX130TM, the company's wholly-owned allogeneic CAR T cell therapy targeting CD70, as a Regenerative Medicine Advanced Therapy (RMAT) for the treatment of Mycosis Fungoides and Sézary Syndrome.
T-cell Therapy Key Market Trends
- CAR T-cell therapies are being used in treatment of solid tumors. CAR T-cell treatment has demonstrated a considerable potential benefit in diffusing midline glioma, a deadly paediatric tumour that affects school-age children and young adults. A study using CAR T cells in animal models to promote prolonged eradication of diffuse midline glioma tumours produced encouraging findings, although some of the animals perished due to toxicity-related problems. For the therapy of brain tumours, intracerebroventricular (ICV) distribution of CAR T was much more effective and less toxic than systemic delivery was found later.
T-cell Therapy Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Co-relates, and Analyses the Data collected utilizing Primary Exploratory Research backed by the robust Secondary Desk research.
According to our Global T cell therapy Market analysis, the need for CAR T-cell treatment is anticipated to develop dramatically as a result of the growing elderly population and the rise in lymphoma and leukaemia cases worldwide. During the projection period for the global T-cell therapy market, it is expected to create lucrative prospects for growth due to the rise in awareness and rise in approval of novel CAR T-cell therapy treatments and promising medications currently in development. Furthermore, a growth in the demand for the best therapies for treating cancer, a rise in the incidence of the disease, advantageous payment policies for CAR T-cell therapy drugs in some countries, and an increase in public knowledge of these drugs. The market for T-cell treatment is rising due to the recent commercialization of CAR-T cell therapy and the fast growing clinical trial activities, both of which are anticipated to present profitable potential for market growth.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 2.83 billion |
| Market size value in 2031 | USD 43.0 billion |
| Growth Rate | 35.3% |
| Base year | 2023 |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
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| Customization scope | Free report customization with purchase. Customization includes:-
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on T-cell Therapy Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on T-cell Therapy Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the T-cell Therapy Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the T-cell Therapy Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the T-cell Therapy Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the T-cell Therapy Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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