USD 2.10 Billion
Tangential Flow Filtration Market Size, Share, Growth Analysis, By Product(Single-use Tangential Flow Filtration Systems, Reusable Tangential Flow Filtration Systems, Membrane Filters, and Filtration Accessories), By Technology(Ultrafiltration, Microfiltration, Nanofiltration, and Others), By Application(Protein Purification, Vaccine and Viral Vectors, Antibody Purification, Raw Material Filtration), By End-use(Pharmaceutical & Biotechnology Companies, Contract Research Organizations & Contract Manufacturing Organizations, and Academic Institutes & Research Laboratories), By Region - Industry Forecast 2025-2032
Report ID:
SQMIG35H2128 |
Region:
Global |
Published Date: April, 2024
Pages:
219
|Tables:
121
|Figures:
77
Tangential Flow Filtration Market Insights
Tangential Flow Filtration Market size was valued at USD 2.34 Billion in 2023 and is poised to grow from USD 2.61 Billion in 2024 to USD 6.26 Billion by 2032, growing at a CAGR of 11.53% during the forecast period (2025-2032).
Tangential flow filtration market is a vital segment belonging to the biotechnology and bioprocessing industries. The tangential flow filtration industry is substantially driven by factors like improvements in membrane technology, rise of biopharmaceuticals, and growing demand for water purification in diverse application areas. The rising demand for biosimilars and biologics is fueling the tangential flow filtration market growth, since these products need effective purification techniques. Modernizations in membrane designs and materials is enhancing product yield and efficiency. The market is also impacted by the rise in research and development and the demand for high-throughput processing. Increased investment in biotech research is fueling the demand for tangential flow filtration systems in pilot plants and laboratories. Furthermore, tangential flow filtration enables high-throughput processing that makes it appropriate for extensive production.
Nonetheless, the market is hindered by significant initial investment, operational complexity, and membrane fouling. The capital cost of these tangential flow filtration and related membranes could be high. This may be an obstacle for smaller companies to adopt and use them efficiently. Also, technical experts needed to maintain and operate these systems may restrict their use in a few settings. Moreover, over time, the membranes may turn fouled, which could result in increased maintenance costs and reduced efficiency. Yet, the tangential flow filtration market is opportune to factors like growing integration with AI, trend towards personalized medicine, and focus on sustainable practices.
US Tangential Flow Filtration Market is poised to grow at sustainable CAGR for the next forecast year.
Market snapshot - 2024-2031
Global Market Size
Largest Segment
Microfiltration
Fastest Growth
Microfiltration
Growth Rate
11.53% CAGR
Global Tangential Flow Filtration Market ($ Bn)
Country Share for North America Region (%)
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Tangential Flow Filtration Market Segmental Analysis
The tangential flow filtration market is segmented on the basis of product, technology, application, end-use, and region. Based on product, the market is segmented into Single-use Tangential Flow Filtration Systems, Reusable Tangential Flow Filtration Systems, Membrane Filters, and Filtration Accessories. In terms of technology, the market is segmented into Ultrafiltration, Microfiltration, Nanofiltration, and Others. Based on Application the market is segmented into Protein Purification, Vaccine and Viral Vectors, Antibody Purification, Raw Material Filtration, Others. Based on End-user the market is segmented into Pharmaceutical & Biotechnology Companies, Contract Research Organizations & Contract Manufacturing Organizations, Academic Institutes & Research Laboratories. Based on region the global Tangential Flow Filtration Market is segmented into North America, Europe, Asia-Pacific, South America, and MEA.
Tangential Flow Filtration Market Analysis by Product
Based on segmentation by product, the market is categorized into single-use tangential flow filtration systems, reusable tangential flow filtration systems, membrane filters, and filtration accessories. The membrane filters segment held a notable tangential flow filtration market share in 2023 and is projected to continue dominance in future as well owing to several key factors including versatility, higher efficiency, cost-effectiveness, scalability, and regulatory acceptance. Membrane filters offer effective purification and separation of biological products. They also hold wide applicability in diverse processes including buffer exchange and protein concentration. They are easily scalable in lab and large-scale production, reduce costs via enhanced production and decreased product costs. Also, they are broadly accepted for quality and safety by regulatory bodies.
On the other hand, the Single-use systems segment held a notable tangential flow filtration market share in the previous years and is expected to lead over the forecast period as well owing to less cross-contamination risk, less operational costs, and easy usage. Single-use systems majorly reduce the contamination risk among the batches. They also eliminate the need for validation and cleaning, which considerably reduces resources and time. Furthermore, easy installation and operation increases user-friendliness, mainly in the small-scale settings, thus driving the segment’s growth. Furthermore, rising demand for scalable and efficient solutions in biopharmaceutical sector is considerably boosting the adoption, affecting the market growth.
Tangential Flow Filtration Market Analysis by End-Use
Based on end-use, the market is segmented into pharmaceutical & biotechnology companies, contract research organizations & contract manufacturing organizations, and academic institutes & research laboratories. The pharmaceutical & biotechnology companies segment held a notable market share in the previous years and is expected to continue dominance over the forecast period as well owing to higher demand for biologics, regulatory compliance, advanced research and development, and better scalability. The rising production of biosimilars and biologics is notably driving the demand for effective and reliable purification methods. Strict regulations are also increasing the need for validated and reliable processes. Other key drivers of the tangential flow filtration industry include major investments in R&D for high filtration needs and scalability option that aids large-scale and small-scale production for biotechnology companies.
On the other hand, the contract research organizations & contract manufacturing organizations segment will hold a remarkable market share in the coming years owing to the growing trend of outsourcing, flexibility, cost-effectiveness, and speedy turnaround. The growing reliance on CMOs and CROs for biopharma processes is considerably driving the demand for tangential flow filtration systems. These systems offer adaptable solutions for different projects and unique production scales. Outsourcing filtration procedures enable consumers to decrease operational costs and emphasize core activities. Also, CMOs and CROs need effective filtration solutions to cater to the strict project timelines. These factors are propelling the growth of the segment.
Global Tangential Flow Filtration Market Size By Product
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Tangential Flow Filtration Market Regional Insights
Geographically, North America dominated the tangential flow filtration market in the previous years and is expected to lead over the forecast period owing to the strong biopharmaceutical sector, innovative research and development, and favorable regulations. The strong presence of key biotechnology and pharmaceutical companies is fueling the need for advanced filtration techniques. Also, growing investment in research and development is driving advancements in filtration technologies and processes. Furthermore, developed frameworks are promoting the adoption of compliant and reliable filtration techniques. The key players profiled in the region include Merck KGaA (MilliporeSigma), Pall Corporation, Thermo Fisher Scientific, Sartorius AG, GE Healthcare Life Sciences, Repligen Corporation, and more.
Asia-Pacific is the fastest-growing region in the global tangential flow filtration market due to the speedy biopharmaceutical growth, heavy investments in biotechnology, and progressing markets. The highly and speedily progressing biopharmaceutical industry with rising demand for biosimilars and biologics is notably impacting the tangential flow filtration industry growth in the region. Increasing investments in healthcare and biotechnology is also driving the adoption of tangential flow filtration. Progressing economies in the region in nations like China, India, and Japan are increasing their manufacturing competencies and infrastructural development. In addition, the market growth is fueled by ongoing advancements in filtration processes and technologies that improve effectiveness and efficiency.
Global Tangential Flow Filtration Market Size By Geography
- Largest
- Fastest
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Tangential Flow Filtration Market Dynamics
Tangential Flow Filtration Market Drivers
Improvements in Filtration Technology
- Innovations in membrane designs, materials, and configuration have notably enhanced selectivity, efficiency, and durability of tangential flow filtration systems. They help the operators with easy usage and help with better outcomes. Enhanced membrane performance considerably decreases fouling time, enhances crop production, and improves throughput. This increases the efficiency of tangential flow filtration systems and increases their attraction among manufacturers.
Rise of Biopharmaceutical Industry
- The biopharmaceutical industry is witnessing substantial growth owing to the rising cases of chronic disorders and heavy demand for biologics like vaccines, monoclonal antibodies, and cell therapies. Tangential flow filtration is vital for the concentration and purification of these complex molecules. This results in increased demand for tangential flow filtration systems.
Tangential Flow Filtration Market Restraints
High Capital and Operation Complexity
- Investing in tangential flow filtration systems and related infrastructure needs higher capital. Hence, this significant expense may refrain startups and a few small companies from implementing TFF technique. This could majorly restrict the growth of the tangential flow filtration market . TFF systems are not easily operated and need expertise for operation. This could be a barrier for the setting who lack needed proficiency.
Low Adoption and Regulatory Challenges
- In a few regions, the awareness for TFF system may be lacking as compared to the conventional filtration methods. This low awareness may hamper the adoption rate, especially in the regions wherein traditional techniques are highly established. While TFF systems are regarded as highly compliant with regulations, navigating the landscape could be challenging. Hence companies should make sure that their filtration process caters to strict protocols that need extensive documentation and validation.
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Tangential Flow Filtration Market Competitive Landscape
As a result of its advantages and swift adoption by bio-manufacturers, the tangential flow filtration industry has been expanding without end for the past few years. Key companies in the TFF market now have worthwhile chances thanks to the rising application in domains like immunology, microbiology, and protein purification procedures. A large product line of filtering products for a variety of applications has also led to considerable income generating. Players use a variety of strategic efforts, including alliances, acquisitions, new product launches, and collaborations, to achieve a competitive advantage.
For instance, Solaris Biotechnology Srl, a producer of bioprocessing equipment with headquarters in Italy, was purchased by Donaldson Company, Inc. in 2021 for USD 40.3 million (EUR 41 million). Since Solaris's portfolio comprised bioreactors, TFF structures, and fermenters, the acquisition increased the company's access to clients in the biopharmaceutical and life science industries. These business initiatives will expand the product line, increase the use of TFF goods in bioprocessing operations, or raise market rivalry, all of which will move the market forward.
Tangential Flow Filtration Market Top Player’s Company Profiles
- Merck KGaA
- Sartorius AG
- GE Healthcare
- Thermo Fisher Scientific Inc.
- Danaher Corporation
- MilliporeSigma
- Repligen Corporation
- 3M Company
- Pall Corporation (a division of Danaher Corporation)
- Parker Hannifin Corporation
- Asahi Kasei Corporation
- Alfa Laval AB
- Eppendorf AG
- Spectrum Laboratories, Inc. (a subsidiary of Repligen Corporation)
- Cole-Parmer Instrument Company LLC
- GEA Group AG
- Novasep Holding S.A.S.
- Filtration Group Corporation
- Starlab Scientific Co., Ltd.
- Alfa Wassermann Separation Technologies S.p.A.
Tangential Flow Filtration Market Recent Developments
- In September 2024, MilliporeSigma launched Mobius ADC Reactor, a single-use reactor solution that is specially designed for the development of ADCs (antibody drug conjugates). ADCs is speedily emerging category of therapeutic agents that offer selective and targeted killing of tumor-affected cells while reducing harm to nearby healthy tissues.
- In September 2024, Sartorius introduced novel lab-focused tangential flow filtration cassettes, named Vivaflow®. This cassette is specially designed to be used in laboratories, with its exceptional design that enables intuitive and fast set-up. It also offers effective diafiltration and ultrafiltration with the help of a single peristaltic pump. This reduces the need to enhance feed flow rates, filtrate flux, and transmembrane pressures.
- In February 2024, Thermo Fisher Scientific Inc. increased its biologics manufacturing plant in Missouri in the United States. This expansion multiplied the company’s production capacity at the St. Louis site in the U.S. to improve production from 2000l - 5000l for manufacturing complex treatments for broader range of diseases like autoimmune conditions, cancer, and rare disorders.
Tangential Flow Filtration Key Market Trends
- Inclination Towards Single-Use Systems: The implementation of single-use systems majorly decreases the risk of cross-contamination and removes the need for validation and cleaning. This increases their attraction among clinical trials and small-scale production facilities. This tangential flow filtration market trend is considerably driven by the rising need for flexibility, cost savings in bio-manufacturing, and quick turnaround times, thus impacting the market growth
- Innovations in Membrane Materials: Latest improvements in membrane design and materials are improving the performance of tangential flow filtration systems. Improvements like enhanced fouling resistance and high-flux membranes enable better separation efficiency and high throughput. These advancements are vital for satisfying the increasing needs of biopharmaceutical production, especially for monoclonal antibodies that are complex molecules.
Tangential Flow Filtration Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
As per SkyQuest analysis, the tangential flow filtration market is considerably progressing due to rising demand for single-use systems, better flexibility and scalability, increasing global health awareness, and progressing markets. In addition, the growing emphasis on research and development for novel therapeutics is also impacting the growth of the market. However, the market is hampered by membrane fouling that reduces the efficiency of filtration, low awareness and adoption of TFF systems, and intensified market competition. North America is anticipated to lead the market due to the strong biopharmaceutical sector, developed regulatory framework, and rising demand for biologics. Nonetheless, a few opportunities for the growth of the tangential flow filtration market include the growing trend for personalized medicine, rising demand for vaccine production, and rising TFF incorporation with automated processes.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 2.10 Billion |
| Market size value in 2031 | USD 5.61 Billion |
| Growth Rate | 11.53% |
| Base year | 2023 |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
|
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Tangential Flow Filtration Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Tangential Flow Filtration Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Tangential Flow Filtration Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Tangential Flow Filtration Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Tangential Flow Filtration Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Tangential Flow Filtration Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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