USD 1.10 Billion
Transfection Technologies Market Size, Share, Growth Analysis, By Method (Reagent-based Method, Instrument-based Method, and Others), By Application(Biomedical Research, Therapeutic Delivery, and Protein Production), By Region - Industry Forecast 2024-2031
Report ID:
SQMIG15A2418 |
Region:
Global |
Published Date: April, 2024
Pages:
183
|Tables:
63
|Figures:
74
Transfection Technologies Market Insights
Global Transfection Technologies Market size was valued at USD 1.10 Billion in 2022 and is poised to grow from USD 1.2 Billion in 2023 to USD 2.69 Billion by 2031, growing at a CAGR of 9.4% in the forecast period (2024-2031).
Growth in chronic diseases and demand for personalized medicines is driving the growth of biopharmaceuticals. Transfection technologies play an important role in the development and manufacture of biopharmaceuticals, thus contributing to the expansion of the market. The field of gene therapy is rapidly evolving with the development of new treatments for genetic diseases and cancer. Viral delivery technologies are required to deliver gene therapy to the target cells, thus increasing demand in this segment. Ongoing research and development efforts result in advanced chemical formulations for transfection reagents, devices, and techniques. These innovations focus on improving transfection, reducing cytotoxicity, cell migration have been increased, allowing for better utilization. The expansion of research in molecular biology, cell biology, and related fields is driving increased demand for transfection technologies. Academic institutions, research labs and pharmaceutical companies are investing in these tools to explore fundamental biology, drug discovery and functional genomics. The market is highly competitive, with big players constantly trying to innovate and differentiate their products. Companies compete based on factors such as product performance, reliability, ease of use, price, and customer support. Regulatory requirements play an important role in shaping the market environment, especially for gene therapy and clinical applications.
Market Snapshot - (2024-2031)
Global Market Size
Largest Segment
Instrument-based
Fastest Growth
Reagent-based
Growth Rate
9.4% CAGR
Global Transfection Technologies Market ($ Bn)
Country Share for Asia Pacific Region (%)
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Transfection Technologies Market Segmental Analysis
Based on method the market is segmented as, reagent-based method, instrument-based method, and others. Based on application the market is segmented into biomedical research, therapeutic delivery, and protein production. Based on Region the market is segmented into North America, Europe, Asia Pacific, Latin America, Middle East & Africa.
Analysis by Method
The instrument-based method is the dominating segment in the market which plays a major role in the transfection technologies market by providing specialized equipment designed to facilitate and efficiently and accurately deliver nucleic acids to cells. Device-based transfection methods, such as electro filter systems, microinjection devices, and gene guns, provide enhanced control over the transfection process compared to chemical or viral-based methods. They allow researchers to optimize parameters such as voltage, pulse duration and injection pressure to achieve high transfection efficiency and cell damage. Device-based transfection systems are versatile and can be adapted to transfect a wide range of cell types including primary cells, stem cells, and transfection-hard cell lines. Their flexibility in scalability, throughput, and experimental optimization provides, make them suitable for a variety of research applications.
The reagent-based method segment is growing significantly due to its low cost, less invasive methods during transfection as well as device-based techniques including electro filtration, biotechnology, microinjection, and laser transfection. Machine-based methods are also less time-consuming and more accurate, all advantages driving the growth of this segment. Nucleic acids can be introduced into eukaryotic cells, unpurified or purified, using transfection reagents. These components include reagents, kits, primer sets, plasmids, and more. New initiatives in reagent-based transfection technologies boost segment growth. For example, in August 2021, PolyPlus launched a transfection reagent for large-scale production of infectious viruses. Due to the increasing demand for viral infections, the introduction of new Polyplus can contribute significantly to mitigating viral infections and hence such new introductions are expected to cater to this segment that has developed in the coming years.
Analysis by Application
Therapeutics delivery is the dominating segment in the market. The therapeutics delivery segment of the transfection technology market includes applications in gene therapy, nucleic acid-based therapeutics, and drug delivery systems. Specifically, gene therapy relies on vector technology to deliver gene therapy or gene editing tools to target cells for the treatment of genetic diseases, cancers, and other diseases. Nucleic acid delivery methods play an important role in gene delivery vectors, such as viral vectors, liposomes and nanoparticles, which are designed to deliver nucleic acids to specific tissues or cells in the development and quality of some of the best and safest. The growing interest in personalized medicine and precision medicine is driving the search for vector technologies engineered to deliver nucleic acids to specific cell types or tissues without success few off-target effects. Advances in therapeutic delivery, coupled with increasing number of clinical trials and approval of gene- and cell-based therapies are fueling the growth of this segment in the transfection technology market.
Biomedical research is the fastest growing segment in the market. Biomedical research is a key driver of innovation and demand in the transfection technology market. Researchers are using techniques to load cells with nucleic acids to study gene function, protein expression, cellular signaling pathways and disease pathways. Transfection technologies play an important role in major research endeavors such as elucidating gene regulation, understanding cellular behavior, and investigating disease mechanisms These studies contribute to scientific development and development of new treatments. Advances in transfection methods, such as viral vectors and gene editing technologies such as CRISPR-Cas9, are often pioneered in biomedical laboratories and subsequently, these innovations find applications in areas such as medical delivery. The biomedical research segment generates demand for a wide range of transfection reagents, devices and services, contributing significantly to the growth of the overall market.
Global Transfection Technologies Market By Method (%)
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Transfection Technologies Market Regional Insights
The market in North America is expected to grow significantly, driven by factors such as increasing prevalence of cancer and other chronic diseases, increasing use of vectors, which require vector-borne pathways body to treat chronic diseases. Rising cancer burden in the US. among people is one of the major drivers of the market. For example, according to American Cancer Society data released in March 2022, the total number of new cancer cases in 2022 is estimated to be 2 million. Among cancer patients, breast cancer is expected to increase the incidence of penile cancer. Transfection technology is widely used in cancer therapy, which is believed to drive the growth of the studied market in the US.
The APAC region dominated the market. Increasing investments in research programs, biopharmaceutical development, and academic collaborations are driving demand for transfection technologies in the region. APAC countries are emerging as an important market for gene therapy research and development. With high patient densities, high healthcare costs, and supportive regulatory frameworks, these countries provide important opportunities for companies involved in transformational technologies. APAC has become a manufacturing hub for biopharmaceuticals and related technologies. Companies in this segment manufacture transfection reagents, devices and consumables catering to both domestic and international markets. Several MNCs form collaborations and strategic partnerships with academic institutions, research organizations and biotechnology companies in the APAC region.
Global Transfection Technologies Market By Geography
- Largest
- Fastest
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Transfection Technologies Market Dynamics
Drivers
Rise in the Introduction of New Products
- Co-transfection involves introducing more than one nucleic acid into a eukaryotic cell. There are many examples of plasmid DNA, combinations of siRNA and plasmid DNA, and multiple miRNAs in the same cell. Generally, the goal of multiple plasmid DNA recombination is to introduce more than one foreign gene into the host cell. One application is the production of viral or hybrid viral constructs containing multiple segments of plasmid DNA. Examples include lentivirus generation from various plasmids such as transfer, envelope, and packaging vectors in HEK293 cells.
Increased Conversion Efficiency
- Transfection efficiency can be demonstrated by co-transfection of small RNAs and plasmid DNA. It is possible to obtain a plasmid containing a luciferase reporter gene whose 3′ UTR is recognized by a specific small RNA such as miRNA, which can bind and inhibit small RNA luciferase expression On the other hand, a specific small RNA has controlling the expression of specific genes as with siRNAs, small RNAs and plasmid DNA are required in combination in RNA interference (RNAi) assays to detect regulatory effects.
Restraints
Rising Cost and Complexity
- Some sterilization methods, especially those involving specialized equipment or proprietary components, can be costly and difficult to implement. Cost up-front costs, ongoing maintenance costs, and the need for specialized expertise may restrict access, especially for academic investigators or small biotech companies with limited budgets some of these are available.
Regulatory Barriers
- Navigating regulatory requirements for clinical translation and marketing in medical applications can be difficult and time-consuming. Transfection technologies used in gene therapy must meet stringent regulatory standards for safety, efficacy, manufacturing and quality control, adding complexity and uncertainty of the scheduling.
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Transfection Technologies Market Competitive Landscape
Thermo Fisher Scientific collaborated with Lonza on joint research and development programs to innovate and improve their transfection technology. The partnership has facilitated technology integration, knowledge sharing and joint innovation, allowing both companies to develop new and improved vector methods, reagents and protocols to treat researchers and meeting the evolving needs of industry professionals. Major competitors operating in the global transfection technologies market and included in this report are Bio-Rad Laboratories, Inc., Harvard Bioscience, Inc., Lonza Group Ltd., Merck KGaA, Mirus Bio LLC, Polyplus-transfection S.A and among others.
Top Player’s Company Profiles
- Lonza (Switzerland)
- Promega Corporation (U.S.)
- Thermo Fisher Scientific Inc. (U.S.)
- Bio-Rad Laboratories, Inc. (U.S.)
- Roche Molecular Systems, Inc. (U.S.)
- QIAGEN (Germany)
- Inovio Pharmaceuticals (U.S.)
- Polyplus Transfection (France)
- Mirus Bio LLC (U.S.)
- Takara Bio Inc. (Japan)
- SignaGen Laboratories (U.S.)
- MaxCyte, Inc. (U.S.)
- Genlantis Inc. (U.S.)
- Techulon (U.S.)
- BioAstrum Corporation (U.S.)
- Altogen Biosystems (U.S.)
- OZ Biosciences (France)
- Boca Scientific, Inc. (U.S.)
- Biontex Laboratories GmbH (Germany)
Recent Developments
- In September 2022, Polyplus, a leading provider of top-of-the-line solutions for research-to-commercial grade advanced biologic and cell gene therapy products, continues to build mRNA support separation The group has launched an in vivo-jetRNA+ transfection reagent for in in vivo mRNA delivery using preformed liposomes.
- In January 2022, Mirus Bio, a leading solutions provider in Gamma Biosciences, launches TransIT-VirusGEN SELECT Transfection Kits for large-scale production of infectious viruses for cell and gene therapy applications.
- In May 2022, AGC Biologics added viral vector suspension technology and the ability to develop and develop gene therapies at its commercial-grade campus in Longmont, Colorado. New capabilities coming online in the third quarter of 2022 Initiated, and complementary to site followers are viral vector and cellular therapeutic offerings.
Transfection Technologies Key Market Trends
- Increasing Adoption of Advanced Delivery Systems: A key market trend in the global transfection technology market is the increasing adoption of advanced delivery systems for nucleic acids. These delivery systems, such as lipid nanoparticles, polymer-based carriers, and viral vectors, offer increased transfection efficiency, improved cell targeting, and reduced cytotoxicity compared to conventional methods about a gaining significant traction in gene therapy, drug delivery, and genome editing applications. In biomedical research and clinical applications, it reflects efforts to develop safe and effective viral technologies to the growing demand has been met.
Transfection Technologies Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
The global transfection technologies market has been witnessing a consistent growth due to growing research sports in molecular biology, rising demand for biopharmaceuticals, and advancements in gene therapy. Key developments within the transfection technologies market consist of the improvement of novel transfection reagents with stepped forward efficiency and decreased cytotoxicity, the integration of automation and high-throughput talents, and the emergence of gene editing technologies including CRISPR-Cas9, which can be regularly used at the side of transfection strategies. Despite advancements, challenges persist in transfection technologies, consisting of optimizing shipping efficiency throughout distinct cell sorts, minimizing cytotoxicity and rancid-target results, and scaling up techniques for business packages.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 1.10 Billion |
| Market size value in 2031 | USD 2.69 Billion |
| Growth Rate | 9.4% |
| Base year | 2023 |
| Forecast period | (2024-2031) |
| Forecast Unit (Value) | USD Billion |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Transfection Technologies Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Transfection Technologies Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Transfection Technologies Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Transfection Technologies Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Transfection Technologies Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Transfection Technologies Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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