USD 893.23 million
Vaccine Adjuvants Market Size, Share, Growth Analysis, By Type(Pathogen-Based Adjuvants and Particulate Adjuvants), By Route of Administration(Intramuscular Route, and Intradermal Route), By Region - Industry Forecast 2024-2031
Report ID:
SQMIG35I2155 |
Region:
Global |
Published Date: March, 2024
Pages:
219
|Tables:
60
|Figures:
75
Vaccine Adjuvants Market Insights
Global Vaccine Adjuvants Market size was valued at USD 893.23 million in 2022 and is poised to grow from USD 1018.19 million in 2023 to USD 2902.45 million by 2031, growing at a CAGR of 13.99% in the forecast period (2024-2031).
An increase in infectious diseases is the overall thrust for the vaccine adjuvants market, which is on the rise. Increased incidence of infectious diseases caused by newly and reemerging microbes makes vaccination more effective against these diseases, thereby resulting in increased demand for vaccinations. Hence, adjuvants assume importance in amplifying immunization efficacy as they render shots stronger as well as a robust defense against infections. For instance, more attention is being given to the aspect of immunization as a primary route to preventing diseases in this upward trend in preventive care all over the world, especially in the wake of the COVID-19 pandemic. This can be attributed to the fact that there is a push towards preventive health care. The immune system identifies certain molecules as alien bodies and attacks them. The molecules referred to here are known as antigens. The adjuvants could provide persistence of the antigen at the injection site, activate the cells of immunity, and modulate the immune response to stimulate a more potent and prolonged response in other ways of stimulation of the immune system. The advancements in R&D in vaccination led to an accumulation of a larger number of innovative vaccines targeting various diseases meant for curing. More vaccine candidates are currently being developed, thereby increasing the demand for adjuvants to enhance the efficacy of vaccines. The market opportunity for vaccine adjuvants is thus expanding.
Market Snapshot - 2024-2031
Global Market Size
Largest Segment
Pathogen-Based Adjuvants
Fastest Growth
Pathogen-Based Adjuvants
Growth Rate
13.99% CAGR
Global Vaccine Adjuvants Market ($ Bn)
Country Share for North America Region (%)
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Vaccine Adjuvants Market Segmental Analysis
Global Vaccine Adjuvants Market is segmented by type, route of administration, and region. Based on type, the market can be segmented into pathogen-based adjuvants, and particulate adjuvants. Based on route of administration, the market is segmented into intramuscular route, and intradermal route. Based on region, the market is segmented into North America, Europe, Asia Pacific, Middle East and Africa, and Latin America.
Vaccine Adjuvants Market Analysis by Disease Type
In the vaccine adjuvants market, infectious diseases were the largest contributor to demand in 2023, especially in the wake of the COVID-19 pandemic. Tremendous investment and innovation have been carried out on vaccines research because of the urgent need for effective vaccinations against a multitude of infectious agents such as RSV, seasonal influenza, and emerging infections. Adjuvants played a critical role in making the vaccinations more stable and effective, which accelerated the immune response. Regulatory agencies gave utmost priority to licensing new formulations while broad-scale immunization campaigns highlighted the needs for strong adjuvant systems. This infectious disease relevance set a benchmark for other vaccination programs while underlining the necessity of preparation for pandemics.
However, the cancer segment will witness a high growth rate for years to come. The increasing interest in therapeutic cancer vaccines that consist of the human immune system targeting and eliminating cancer cells is the outcome of innovations manifested in personalized medicine and cancer immunotherapy. To make these vaccines more effective, advances in research continue to produce even more creative adjuvants as more patients will then be provided with healthier conditions. As more and more people become aware of the possibility of cancer vaccines, regulatory approvals to manufacture them are now starting to be granted. This fast-emerging field looks bright for a brighter future when adjuvants that would work well together can probably enhance cancer therapy and provide hope for patients everywhere.
Vaccine Adjuvants Market Analysis by Route of Administration
The highest share is held by intramuscular routes due to the larger immunological specificity as of 2023. HPV, influenza, meningitis, and many more are used heavily in this mode of vaccine delivery. The administration route plays a crucial role in determining the efficiency of vaccines. For example, alum salts, which are most used as parenteral adjuvants have little or no action when administered by mouth or nose. Due to this, the intramuscular portion accounts for the largest market share because it has a track record of eliciting an immunologic response at a high level.
The growth in the vaccination adjuvants market in the intradermal route is expected to be the fastest pace. Such a difference, compared with others, confers advantages in longer absorption and the duration of effect. The above factors are among the causes that have led to the increase in intradermal vaccination demand. Some adjuvants that are intradermally applied, such as TLR3-Ligand Poly (I:C), have been proved to induce mucosal antibody responses and confer immunity against genital HSV-2 infection. The market is growing at a very fast rate due to increased awareness that the intradermal route can enhance the efficacy of vaccination.
Global Vaccine Adjuvants Market by Disease Type
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Vaccine Adjuvants Market Regional Insights
Due to the well-established healthcare system and significant investments in R&D, North America accounted for the highest share in the vaccine adjuvants market revenue in 2023. The region houses large industrial companies that feature a wide array of vaccine adjuvants, which are used in commercial as well as research-oriented fields. It has leading biotech and pharmaceutical firms, which foster innovation and make it relatively easier to produce compositions that work as adjuvants. In addition, continued technical advances in adjuvant mechanisms and vaccine delivery modalities for various disease applications are fueling growth in North America and ensuring strong public health plans and responses to emerging health risks.
On the other hand, vaccine adjuvants market in Asia-Pacific is expected to experience a fasted CAGR during the forecast period. This developing number of people infected with infectious diseases coupled with the rising healthcare cost along with rapid advancement in scientific research directly paving the way toward vaccine research are some of the reasons driving the trend. The rise in infectious diseases, due to drugs and medicines, and chronic diseases, in countries such as China, India, and Southeast Asia is driving this demand for a potent adjuvant. Programs undertaken by the government, concerning public health awareness and increased vaccination coverage, are also supporting dynamic market growth in this region, making it a significant player in the global arena.
Global Vaccine Adjuvants Market By Geography
- Largest
- Fastest
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Vaccine Adjuvants Market Dynamics
Vaccine Adjuvants Market Drivers
Rising Demand for Vaccines
- The increased global health concerns brought by the COVID-19 pandemic and up need for higher levels of vaccinations, especially adjuvant-based. This is attributed to the requirements for an effective vaccination approach toward various infectious diseases and new emerging pathogens in preserving community immunity. Accordingly, the vaccine manufacturing continues to find ways to enhance vaccination potency by investing in the latest technology in adjuvant.
Technological development in biotechnology
- Developed due to important technical progress is that of new adjuvants for vaccination. Durable vaccination effect and the immune-boosting effect along with reduction in the side effect occurs due to the innovation research on the newer compositions of adjuvants. Due to these innovations, it becomes easy to generate more effective vaccines against greater numbers of diseases; hence, it benefits both the patient and the healthcare worker. This is why the industry of vaccination adjuvants has expanded extensively.
Restraints
Regulatory Challenges
- The licensing of vaccine adjuvants is constrained by very major regulatory barriers in the market. Stricter rules may cause new adjuvants to enter the market later than they need to; this can also help increase costs for manufacturers, an additional overhead that could hinder growth in the market. It may take a lot of resources to navigate an elaborate regulatory process and be sure that there are no compliance issues with safety regulations- the problem of the small business trying to disturb the market.
Public Reluctance to Vaccinate
- Public perception and sensitivity towards vaccinations are major barriers to the vaccine adjuvant market. A decrease in vaccination rates, often resulting from misinformation or an apprehension surrounding vaccination safety, will directly affect the vaccine adjuvant market. Social media, cultural practices, or a bad experience in previous exposure can influence this hesitance, which knocks on further into public health campaigns and decreases the demand for new vaccines, especially those containing adjuvants.
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Vaccine Adjuvants Market Competitive Landscape
Business diversity in developing and meeting the emergent demand for adjuvant products characterizes the global vaccine adjuvants market. Market players are investing considerable funds in R&D with a focus on increasing the safety and efficacy of adjuvants. In addition, firms often adopt partnerships, collaborations, and acquisitions as steps to boost their market position. The competitive environment increased the market competitiveness, and it has also grown overall because it encourages an ongoing attempt to upgrade the production techniques, create new adjuvant formulas, and new technology.
Vaccine Adjuvants Market Top Player’s Company Profiles
- GlaxoSmithKline plc (United Kingdom)
- SEPPIC (France)
- InvivoGen (US)
- Brenntag Biosector (Denmark)
- Avanti Polar Lipids, Inc. (US)
- Vaxine Pty Ltd. (Australia)
- SPI Pharma (US)
- OZ Biosciences (France)
- CureVac AG (Germany)
- Adjuvatis (France)
- Advanced BioAdjuvants Corporation (US)
- Adjuvance Technologies Inc. (US)
- SDA Bio (Italy)
- Bio Products Laboratory Ltd. (United Kingdom)
- GSK Vaccines GmbH (Germany)
- Mucosis B.V. (Netherlands)
- NanoBio Corporation (US)
Vaccine Adjuvants Market Recent Developments
- May 2023: US companies Amyris and Botanical Solutions Inc (BSI) partnered with UK specialty chemicals company Croda through collaboration agreements to produce renewable vaccination adjuvants.
- January 2023: Elicio Therapeutics is developing multiple immunotherapies based on its proprietary lymph node-targeting Amphiphile technology, AMP to develop ELI-002, a therapeutic cancer vaccine designed to target mKRAS-driven tumors. The firm reached a definitive merger agreement with Angion Biomedica Corp. The firm there focuses on the engineering of lymph node-targeted adjuvants and vaccines for different aggressive cancers and infectious diseases.
- March 2022: Croda received an exclusive license to market adjuvants for the SSI CAF vaccine. The vaccine adjuvants business is anticipated to expand with the impression that SSI cationic adjuvants have massive prospects for future vaccine development.
Vaccine Adjuvants Key Market Trends
- Personalized Immunization Plans: One of the major and latest approaches observed in the vaccine adjuvants market is the shift toward customized vaccination strategies. Researchers have started to prepare specific vaccines depending on the uniqueness of every patient, such as genetic and immune system-specific differences. To phrase it simply, this approach seeks to further enhance the effectiveness of vaccinations, hence the outcomes of patients, by enabling a more efficient immunization strategy, which would involve specific adjuvants designed for various patients to deliver the most efficacious responses.
- Combination of Vaccines: Combination vaccine manufacturing, in which a lot of adjuvants and antigens are integrated into a single formulation, is becoming increasingly popular. This method aims to increase public compliance by requiring fewer injections, thus speeding up the process of vaccination. In combination with several vaccinations, adjuvants are predicted to enhance immune responses against diverse diseases, thereby improving protection and more effective use of healthcare services, which will drive the growth of the market.
Vaccine Adjuvants Market SkyQuest Analysis
SkyQuest’s ABIRAW (Advanced Business Intelligence, Research & Analysis Wing) is our Business Information Services team that Collects, Collates, Correlates, and Analyses the Data collected by means of Primary Exploratory Research backed by robust Secondary Desk research.
As per SkyQuest analysis, the vaccine adjuvants market is predicted to grow substantially with a hike in vaccination rates and technical breaks through. Currently, the market share is dominated by North America due to continuous innovation and robust health care infrastructure. Asia-Pacific is showing significant growth due to increased healthcare costs and infectious diseases. However, to fully utilize the potential of the market, issues of public shyness and barriers of regulations will have to be overcome. With vaccine adjuvants looking to fight infectious and chronic diseases, this vista promises a brighter future with high effectiveness and a wider health impact as custom immunization plans and combination vaccinations become a ubiquitous phenomenon in a relatively short timeframe.
| Report Metric | Details |
|---|---|
| Market size value in 2022 | USD 893.23 million |
| Market size value in 2031 | USD 2902.45 million |
| Growth Rate | 13.99% |
| Base year | 2023 |
| Forecast period | 2024-2031 |
| Forecast Unit (Value) | USD Million |
| Segments covered |
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| Regions covered | North America (US, Canada), Europe (Germany, France, United Kingdom, Italy, Spain, Rest of Europe), Asia Pacific (China, India, Japan, Rest of Asia-Pacific), Latin America (Brazil, Rest of Latin America), Middle East & Africa (South Africa, GCC Countries, Rest of MEA) |
| Companies covered |
|
| Customization scope | Free report customization with purchase. Customization includes:-
|
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Table Of Content
Executive Summary
Market overview
- Exhibit: Executive Summary – Chart on Market Overview
- Exhibit: Executive Summary – Data Table on Market Overview
- Exhibit: Executive Summary – Chart on Vaccine Adjuvants Market Characteristics
- Exhibit: Executive Summary – Chart on Market by Geography
- Exhibit: Executive Summary – Chart on Market Segmentation
- Exhibit: Executive Summary – Chart on Incremental Growth
- Exhibit: Executive Summary – Data Table on Incremental Growth
- Exhibit: Executive Summary – Chart on Vendor Market Positioning
Parent Market Analysis
Market overview
Market size
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- SWOT Analysis
KEY MARKET INSIGHTS
- Technology Analysis
- (Exhibit: Data Table: Name of technology and details)
- Pricing Analysis
- (Exhibit: Data Table: Name of technology and pricing details)
- Supply Chain Analysis
- (Exhibit: Detailed Supply Chain Presentation)
- Value Chain Analysis
- (Exhibit: Detailed Value Chain Presentation)
- Ecosystem Of the Market
- Exhibit: Parent Market Ecosystem Market Analysis
- Exhibit: Market Characteristics of Parent Market
- IP Analysis
- (Exhibit: Data Table: Name of product/technology, patents filed, inventor/company name, acquiring firm)
- Trade Analysis
- (Exhibit: Data Table: Import and Export data details)
- Startup Analysis
- (Exhibit: Data Table: Emerging startups details)
- Raw Material Analysis
- (Exhibit: Data Table: Mapping of key raw materials)
- Innovation Matrix
- (Exhibit: Positioning Matrix: Mapping of new and existing technologies)
- Pipeline product Analysis
- (Exhibit: Data Table: Name of companies and pipeline products, regional mapping)
- Macroeconomic Indicators
COVID IMPACT
- Introduction
- Impact On Economy—scenario Assessment
- Exhibit: Data on GDP - Year-over-year growth 2016-2022 (%)
- Revised Market Size
- Exhibit: Data Table on Vaccine Adjuvants Market size and forecast 2021-2027 ($ million)
- Impact Of COVID On Key Segments
- Exhibit: Data Table on Segment Market size and forecast 2021-2027 ($ million)
- COVID Strategies By Company
- Exhibit: Analysis on key strategies adopted by companies
MARKET DYNAMICS & OUTLOOK
- Market Dynamics
- Exhibit: Impact analysis of DROC, 2021
- Drivers
- Opportunities
- Restraints
- Challenges
- Exhibit: Impact analysis of DROC, 2021
- Regulatory Landscape
- Exhibit: Data Table on regulation from different region
- SWOT Analysis
- Porters Analysis
- Competitive rivalry
- Exhibit: Competitive rivalry Impact of key factors, 2021
- Threat of substitute products
- Exhibit: Threat of Substitute Products Impact of key factors, 2021
- Bargaining power of buyers
- Exhibit: buyers bargaining power Impact of key factors, 2021
- Threat of new entrants
- Exhibit: Threat of new entrants Impact of key factors, 2021
- Bargaining power of suppliers
- Exhibit: Threat of suppliers bargaining power Impact of key factors, 2021
- Competitive rivalry
- Skyquest special insights on future disruptions
- Political Impact
- Economic impact
- Social Impact
- Technical Impact
- Environmental Impact
- Legal Impact
Market Size by Region
- Chart on Market share by geography 2021-2027 (%)
- Data Table on Market share by geography 2021-2027(%)
- North America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- USA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Canada
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Europe
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Germany
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Spain
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- France
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- UK
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Europe
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Asia Pacific
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- China
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- India
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Japan
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Korea
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of Asia Pacific
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Latin America
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- Brazil
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of South America
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Middle East & Africa (MEA)
- Chart on Market share by country 2021-2027 (%)
- Data Table on Market share by country 2021-2027(%)
- GCC Countries
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- South Africa
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
- Rest of MEA
- Exhibit: Chart on Market share 2021-2027 (%)
- Exhibit: Market size and forecast 2021-2027 ($ million)
KEY COMPANY PROFILES
- Competitive Landscape
- Total number of companies covered
- Exhibit: companies covered in the report, 2021
- Top companies market positioning
- Exhibit: company positioning matrix, 2021
- Top companies market Share
- Exhibit: Pie chart analysis on company market share, 2021(%)
- Total number of companies covered
Methodology
For the Vaccine Adjuvants Market, our research methodology involved a mixture of primary and secondary data sources. Key steps involved in the research process are listed below:
1. Information Procurement: This stage involved the procurement of Market data or related information via primary and secondary sources. The various secondary sources used included various company websites, annual reports, trade databases, and paid databases such as Hoover's, Bloomberg Business, Factiva, and Avention. Our team did 45 primary interactions Globally which included several stakeholders such as manufacturers, customers, key opinion leaders, etc. Overall, information procurement was one of the most extensive stages in our research process.
2. Information Analysis: This step involved triangulation of data through bottom-up and top-down approaches to estimate and validate the total size and future estimate of the Vaccine Adjuvants Market.
3. Report Formulation: The final step entailed the placement of data points in appropriate Market spaces in an attempt to deduce viable conclusions.
4. Validation & Publishing: Validation is the most important step in the process. Validation & re-validation via an intricately designed process helped us finalize data points to be used for final calculations. The final Market estimates and forecasts were then aligned and sent to our panel of industry experts for validation of data. Once the validation was done the report was sent to our Quality Assurance team to ensure adherence to style guides, consistency & design.
Analyst Support
Customization Options
With the given market data, our dedicated team of analysts can offer you the following customization options are available for the Vaccine Adjuvants Market:
Product Analysis: Product matrix, which offers a detailed comparison of the product portfolio of companies.
Regional Analysis: Further analysis of the Vaccine Adjuvants Market for additional countries.
Competitive Analysis: Detailed analysis and profiling of additional Market players & comparative analysis of competitive products.
Go to Market Strategy: Find the high-growth channels to invest your marketing efforts and increase your customer base.
Innovation Mapping: Identify racial solutions and innovation, connected to deep ecosystems of innovators, start-ups, academics, and strategic partners.
Category Intelligence: Customized intelligence that is relevant to their supply Markets will enable them to make smarter sourcing decisions and improve their category management.
Public Company Transcript Analysis: To improve the investment performance by generating new alpha and making better-informed decisions.
Social Media Listening: To analyze the conversations and trends happening not just around your brand, but around your industry as a whole, and use those insights to make better Marketing decisions.
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